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Analogs

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Popular Name: 2,2-dimethyl-1-(3-phenoxyazetidin-1-yl)propan-1-one 2,2-dimethyl-1-(3-phenoxyazetidi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.90 6.19 -8.9 0 3 0 30 233.311 3 ↓

Analogs

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Popular Name: 3-(2,3-Difluorophenoxy)azetidine 3-(2,3-Difluorophenoxy)azetidine

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.86 3.43 -48.8 2 2 1 26 186.181 2 ↓
Hi High (pH 8-9.5) 1.86 1.73 -6.79 1 2 0 21 185.173 2 ↓

Analogs

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Popular Name: 3-(2-bromo-4-nitro-phenoxy)azetidine 3-(2-bromo-4-nitro-phenoxy)azeti…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 4.68 -53.61 2 5 1 72 274.094 3 ↓
Hi High (pH 8-9.5) 2.32 2.98 -5.81 1 5 0 67 273.086 3 ↓

Analogs

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Popular Name: 3-(2,3-difluoro-6-nitro-phenoxy)azetidine 3-(2,3-difluoro-6-nitro-phenoxy)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 4.91 -40.99 2 5 1 72 231.178 3 ↓
Hi High (pH 8-9.5) 1.77 3.21 -6.74 1 5 0 67 230.17 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-chloro-benzamide 2-(azetidin-3-yloxy)-5-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.60 1.87 -43.02 4 4 1 69 227.671 3 ↓
Hi High (pH 8-9.5) 1.60 0.17 -12.45 3 4 0 64 226.663 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-6-chloro-benzonitrile 2-(azetidin-3-yloxy)-6-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.97 4.13 -51.59 2 3 1 50 209.656 2 ↓
Hi High (pH 8-9.5) 1.97 2.43 -8.49 1 3 0 45 208.648 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-6-chloro-benzamide 2-(azetidin-3-yloxy)-6-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.03 0.42 -51.92 4 4 1 69 227.671 3 ↓
Hi High (pH 8-9.5) 1.03 -1.28 -9.97 3 4 0 64 226.663 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-chloro-benzonitrile 2-(azetidin-3-yloxy)-5-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.99 4.23 -49.7 2 3 1 50 209.656 2 ↓
Hi High (pH 8-9.5) 1.99 2.52 -6.22 1 3 0 45 208.648 2 ↓

Analogs

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Popular Name: 3-(4-methyl-3-nitro-phenoxy)azetidine 3-(4-methyl-3-nitro-phenoxy)azet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.96 4.63 -52.65 2 5 1 72 209.225 3 ↓
Hi High (pH 8-9.5) 1.96 2.93 -7.3 1 5 0 67 208.217 3 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-2-chloro-benzamide 4-(azetidin-3-yloxy)-2-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 0.6 -49.87 4 4 1 69 227.671 3 ↓
Hi High (pH 8-9.5) 1.05 -1.1 -9.78 3 4 0 64 226.663 3 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-3-chloro-benzonitrile 4-(azetidin-3-yloxy)-3-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.99 4.25 -50.62 2 3 1 50 209.656 2 ↓
Hi High (pH 8-9.5) 1.99 2.55 -5.77 1 3 0 45 208.648 2 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-3-chloro-benzamide 4-(azetidin-3-yloxy)-3-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 0.65 -49.08 4 4 1 69 227.671 3 ↓
Hi High (pH 8-9.5) 1.05 -1.05 -7.76 3 4 0 64 226.663 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-4-chloro-benzamide 2-(azetidin-3-yloxy)-4-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.60 1.88 -43.92 4 4 1 69 227.671 3 ↓
Hi High (pH 8-9.5) 1.60 0.18 -9.83 3 4 0 64 226.663 3 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-2-chloro-benzonitrile 4-(azetidin-3-yloxy)-2-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.99 4.11 -49.47 2 3 1 50 209.656 2 ↓
Hi High (pH 8-9.5) 1.99 2.41 -5.73 1 3 0 45 208.648 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-4-chloro-benzonitrile 2-(azetidin-3-yloxy)-4-chloro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.99 4.24 -46.06 2 3 1 50 209.656 2 ↓
Hi High (pH 8-9.5) 1.99 2.54 -5.8 1 3 0 45 208.648 2 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-3-fluoro-benzonitrile 4-(azetidin-3-yloxy)-3-fluoro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.48 3.77 -51.19 2 3 1 50 193.201 2 ↓
Hi High (pH 8-9.5) 1.48 2.07 -6.5 1 3 0 45 192.193 2 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-3-fluoro-benzamide 4-(azetidin-3-yloxy)-3-fluoro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.54 0.17 -49.59 4 4 1 69 211.216 3 ↓
Hi High (pH 8-9.5) 0.54 -1.53 -8.39 3 4 0 64 210.208 3 ↓

Analogs

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Popular Name: 3-(3-fluoro-2-nitro-phenoxy)azetidine 3-(3-fluoro-2-nitro-phenoxy)azet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.66 4.21 -55.19 2 5 1 72 213.188 3 ↓
Hi High (pH 8-9.5) 1.66 2.51 -11.63 1 5 0 67 212.18 3 ↓

Analogs

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Popular Name: 3-(3-fluoro-5-nitro-phenoxy)azetidine 3-(3-fluoro-5-nitro-phenoxy)azet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 4.07 -51.14 2 5 1 72 213.188 3 ↓
Hi High (pH 8-9.5) 1.68 2.37 -4.45 1 5 0 67 212.18 3 ↓

Analogs

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Popular Name: 3-(2,4-dinitrophenoxy)azetidine 3-(2,4-dinitrophenoxy)azetidine

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.47 5.49 -61.35 2 8 1 117 240.195 4 ↓
Hi High (pH 8-9.5) 1.47 3.78 -9.94 1 8 0 113 239.187 4 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-4-methyl-benzonitrile 2-(azetidin-3-yloxy)-4-methyl-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.76 4.38 -46.95 2 3 1 50 189.238 2 ↓
Hi High (pH 8-9.5) 1.76 2.68 -7.01 1 3 0 45 188.23 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-4-methyl-benzamide 2-(azetidin-3-yloxy)-4-methyl-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.37 2.02 -44.26 4 4 1 69 207.253 3 ↓
Hi High (pH 8-9.5) 1.37 0.31 -10.77 3 4 0 64 206.245 3 ↓

Analogs

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Popular Name: 3-[2,4-bis(methylsulfonyl)phenoxy]azetidine 3-[2,4-bis(methylsulfonyl)phenox…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.27 -1.13 -64.6 2 6 1 94 306.385 4 ↓
Hi High (pH 8-9.5) -0.27 -2.83 -17.96 1 6 0 90 305.377 4 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-N-methyl-3-nitro-benzenesulfonamide 4-(azetidin-3-yloxy)-N-methyl-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.58 0.95 -61.4 3 8 1 118 288.305 5 ↓
Hi High (pH 8-9.5) 0.58 -0.75 -14.14 2 8 0 113 287.297 5 ↓

Analogs

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Popular Name: 3-(4-ethylsulfonylphenoxy)azetidine 3-(4-ethylsulfonylphenoxy)azetidine

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.87 1.71 -50.84 2 4 1 60 242.32 4 ↓
Hi High (pH 8-9.5) 0.87 0.01 -12.13 1 4 0 55 241.312 4 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-N-isopropyl-benzenesulfonamide 4-(azetidin-3-yloxy)-N-isopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.37 0.88 -50.26 3 5 1 72 271.362 5 ↓
Hi High (pH 8-9.5) 1.37 -0.74 -10.61 2 5 0 67 270.354 5 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-N-isopropyl-benzenesulfonamide 2-(azetidin-3-yloxy)-N-isopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.32 1.43 -54.43 3 5 1 72 271.362 5 ↓
Hi High (pH 8-9.5) 1.32 -0.22 -10.17 2 5 0 67 270.354 5 ↓

Analogs

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Popular Name: 3-(4-methylsulfonyl-2-nitro-phenoxy)azetidine 3-(4-methylsulfonyl-2-nitro-phen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.38 2.32 -61.92 2 7 1 106 273.29 4 ↓
Hi High (pH 8-9.5) 0.38 0.62 -16.23 1 7 0 101 272.282 4 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)benzenesulfonamide 4-(azetidin-3-yloxy)benzenesulfo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.32 -1.74 -52.59 4 5 1 86 229.281 3 ↓
Hi High (pH 8-9.5) 0.32 -3.44 -10.03 3 5 0 81 228.273 3 ↓

Analogs

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Popular Name: 3-[2-(trifluoromethylsulfonyl)phenoxy]azetidine 3-[2-(trifluoromethylsulfonyl)ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.44 2 -48.73 2 4 1 60 282.263 4 ↓
Hi High (pH 8-9.5) 4.44 0.3 -7.65 1 4 0 55 281.255 4 ↓

Analogs

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Popular Name: 3-[4-(difluoromethylsulfonyl)phenoxy]azetidine 3-[4-(difluoromethylsulfonyl)phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 1.22 -48.4 2 4 1 60 264.273 4 ↓
Hi High (pH 8-9.5) 1.05 -0.48 -10.35 1 4 0 55 263.265 4 ↓

Analogs

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Popular Name: 3-[4-nitro-3-(trifluoromethyl)phenoxy]azetidine 3-[4-nitro-3-(trifluoromethyl)ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.41 4.76 -59.01 2 5 1 72 263.195 4 ↓
Hi High (pH 8-9.5) 2.41 3.06 -8.27 1 5 0 67 262.187 4 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-N,N-dimethyl-benzenesulfonamide 4-(azetidin-3-yloxy)-N,N-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.94 1.28 -50.05 2 5 1 63 257.335 4 ↓
Hi High (pH 8-9.5) 0.94 -0.42 -10.57 1 5 0 59 256.327 4 ↓

Analogs

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Popular Name: 3-(2-methylsulfonylphenoxy)azetidine 3-(2-methylsulfonylphenoxy)azeti…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.89 1.33 -54.02 2 4 1 60 228.293 3 ↓
Hi High (pH 8-9.5) 0.89 -0.37 -11.14 1 4 0 55 227.285 3 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-N-propyl-benzenesulfonamide 4-(azetidin-3-yloxy)-N-propyl-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 1.08 -50.23 3 5 1 72 271.362 6 ↓
Hi High (pH 8-9.5) 1.57 -0.62 -10.52 2 5 0 67 270.354 6 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-N-propyl-benzenesulfonamide 2-(azetidin-3-yloxy)-N-propyl-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.53 1.49 -54.89 3 5 1 72 271.362 6 ↓
Hi High (pH 8-9.5) 1.53 -0.21 -9.91 2 5 0 67 270.354 6 ↓

Analogs

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Popular Name: 3-[2-(difluoromethylsulfonyl)phenoxy]azetidine 3-[2-(difluoromethylsulfonyl)phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.45 1.8 -49.22 2 4 1 60 264.273 4 ↓
Hi High (pH 8-9.5) 1.45 0.1 -9.12 1 4 0 55 263.265 4 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-N-methyl-benzenesulfonamide 4-(azetidin-3-yloxy)-N-methyl-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.70 -0.53 -50.57 3 5 1 72 243.308 4 ↓
Hi High (pH 8-9.5) 0.70 -2.23 -11.11 2 5 0 67 242.3 4 ↓

Analogs

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Popular Name: 3-(2-ethylsulfonylphenoxy)azetidine 3-(2-ethylsulfonylphenoxy)azetidine

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.26 2.22 -54.11 2 4 1 60 242.32 4 ↓
Hi High (pH 8-9.5) 1.26 0.52 -10.86 1 4 0 55 241.312 4 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-N-ethyl-benzenesulfonamide 2-(azetidin-3-yloxy)-N-ethyl-ben…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.02 0.78 -54.38 3 5 1 72 257.335 5 ↓
Hi High (pH 8-9.5) 1.02 -0.92 -10.1 2 5 0 67 256.327 5 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-N-ethyl-benzenesulfonamide 4-(azetidin-3-yloxy)-N-ethyl-ben…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.07 0.31 -50.3 3 5 1 72 257.335 5 ↓
Hi High (pH 8-9.5) 1.07 -1.4 -10.73 2 5 0 67 256.327 5 ↓

Analogs

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Popular Name: 3-(4-propylsulfonylphenoxy)azetidine 3-(4-propylsulfonylphenoxy)azeti…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.38 2.51 -51.78 2 4 1 60 256.347 5 ↓
Hi High (pH 8-9.5) 1.38 0.81 -10.07 1 4 0 55 255.339 5 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)benzenesulfonamide 2-(azetidin-3-yloxy)benzenesulfo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.27 -1.27 -52.93 4 5 1 86 229.281 3 ↓
Hi High (pH 8-9.5) 0.27 -2.97 -10.93 3 5 0 81 228.273 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-N-methyl-benzenesulfonamide 2-(azetidin-3-yloxy)-N-methyl-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.65 -0.06 -54.08 3 5 1 72 243.308 4 ↓
Hi High (pH 8-9.5) 0.65 -1.75 -10.33 2 5 0 67 242.3 4 ↓

Analogs

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Popular Name: 3-[4-(trifluoromethylsulfonyl)phenoxy]azetidine 3-[4-(trifluoromethylsulfonyl)ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.05 1.42 -48.94 2 4 1 60 282.263 4 ↓
Hi High (pH 8-9.5) 4.05 -0.28 -8.2 1 4 0 55 281.255 4 ↓

Analogs

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Popular Name: 3-(2-propylsulfonylphenoxy)azetidine 3-(2-propylsulfonylphenoxy)azeti…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 3.02 -54.23 2 4 1 60 256.347 5 ↓
Hi High (pH 8-9.5) 1.77 1.32 -10.68 1 4 0 55 255.339 5 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-N,N-dimethyl-benzenesulfonamide 2-(azetidin-3-yloxy)-N,N-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.89 1.74 -53.6 2 5 1 63 257.335 4 ↓
Hi High (pH 8-9.5) 0.89 0.04 -10.18 1 5 0 59 256.327 4 ↓

Analogs

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Popular Name: 4-(azetidin-3-yloxy)-3-nitro-benzamide 4-(azetidin-3-yloxy)-3-nitro-ben…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.33 1.56 -65.78 4 7 1 115 238.223 4 ↓
Hi High (pH 8-9.5) 0.33 -0.14 -16.96 3 7 0 110 237.215 4 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-nitro-benzamide 2-(azetidin-3-yloxy)-5-nitro-ben…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.88 2.06 -53.19 4 7 1 115 238.223 4 ↓
Hi High (pH 8-9.5) 0.88 0.36 -10.38 3 7 0 110 237.215 4 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-6-fluoro-benzonitrile 2-(azetidin-3-yloxy)-6-fluoro-be…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.45 3.75 -52.58 2 3 1 50 193.201 2 ↓
Hi High (pH 8-9.5) 1.45 2.05 -9.33 1 3 0 45 192.193 2 ↓

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

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