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ZINC Item

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48630400

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-[(1S,2Z)-2-amino-2-hydroxyimino-1-phenyl-ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1S,2Z)-2-amino-2-hydrox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.50	0.71	-11.38	4	6	0	97	263.297	4	↓ MOL2 SDF SMILES Flexibase

48630401

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-[(1R,2Z)-2-amino-2-hydroxyimino-1-phenyl-ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1R,2Z)-2-amino-2-hydrox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.50	0.41	-14.55	4	6	0	97	263.297	4	↓ MOL2 SDF SMILES Flexibase

48630410

Analogs

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Popular Name: (3R)-N-[(3-sulfamoylphenyl)methyl]tetrahydrofuran-3-carboxamide (3R)-N-[(3-sulfamoylphenyl)methy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.03	-1.4	-16.92	3	6	0	98	284.337	4	↓ MOL2 SDF SMILES Flexibase

48630411

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(3-sulfamoylphenyl)methyl]tetrahydrofuran-3-carboxamide (3S)-N-[(3-sulfamoylphenyl)methy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.03	-1.4	-15.86	3	6	0	98	284.337	4	↓ MOL2 SDF SMILES Flexibase

48630434

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-[(1S)-1-(3-sulfamoylphenyl)ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1S)-1-(3-sulfamoylpheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.53	-0.57	-17.45	3	6	0	98	298.364	4	↓ MOL2 SDF SMILES Flexibase

48630435

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-[(1R)-1-(3-sulfamoylphenyl)ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1R)-1-(3-sulfamoylpheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.53	-0.57	-18.08	3	6	0	98	298.364	4	↓ MOL2 SDF SMILES Flexibase

48630436

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(1S)-1-(3-sulfamoylphenyl)ethyl]tetrahydrofuran-3-carboxamide (3S)-N-[(1S)-1-(3-sulfamoylpheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.53	-0.56	-16.72	3	6	0	98	298.364	4	↓ MOL2 SDF SMILES Flexibase

48630437

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(1R)-1-(3-sulfamoylphenyl)ethyl]tetrahydrofuran-3-carboxamide (3S)-N-[(1R)-1-(3-sulfamoylpheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.53	-0.56	-16.76	3	6	0	98	298.364	4	↓ MOL2 SDF SMILES Flexibase

52879121

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-phenyl-2-[[(3R)-tetrahydrofuran-3-carbonyl]amino]propanoic (2R)-2-phenyl-2-[[(3R)-tetrahydr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.18	5.52	-59.6	1	5	-1	78	262.285	4	↓ MOL2 SDF SMILES Flexibase

52879123

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-2-phenyl-2-[[(3R)-tetrahydrofuran-3-carbonyl]amino]propanoic (2S)-2-phenyl-2-[[(3R)-tetrahydr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.18	5.52	-56.67	1	5	-1	78	262.285	4	↓ MOL2 SDF SMILES Flexibase

52879125

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-phenyl-2-[[(3S)-tetrahydrofuran-3-carbonyl]amino]propanoic (2R)-2-phenyl-2-[[(3S)-tetrahydr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.18	5.55	-55.14	1	5	-1	78	262.285	4	↓ MOL2 SDF SMILES Flexibase

52879128

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-2-phenyl-2-[[(3S)-tetrahydrofuran-3-carbonyl]amino]propanoic (2S)-2-phenyl-2-[[(3S)-tetrahydr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.18	5.55	-57.59	1	5	-1	78	262.285	4	↓ MOL2 SDF SMILES Flexibase

52898648

Analogs

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Popular Name: (3R)-N-[[4-(2-aminoethyl)phenyl]methyl]tetrahydrofuran-3-carboxamide (3R)-N-[[4-(2-aminoethyl)phenyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.29	2.47	-52.89	4	4	1	66	249.334	5	↓ MOL2 SDF SMILES Flexibase

52898650

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[[4-(2-aminoethyl)phenyl]methyl]tetrahydrofuran-3-carboxamide (3S)-N-[[4-(2-aminoethyl)phenyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.29	2.47	-52.13	4	4	1	66	249.334	5	↓ MOL2 SDF SMILES Flexibase

52925871

Analogs

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Popular Name: (3R)-N-[(3-aminophenyl)methyl]tetrahydrofuran-3-carboxamide (3R)-N-[(3-aminophenyl)methyl]te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.36	1.51	-8.74	3	4	0	64	220.272	3	↓ MOL2 SDF SMILES Flexibase

52925872

Analogs

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Popular Name: (3S)-N-[(3-aminophenyl)methyl]tetrahydrofuran-3-carboxamide (3S)-N-[(3-aminophenyl)methyl]te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.36	1.52	-7.96	3	4	0	64	220.272	3	↓ MOL2 SDF SMILES Flexibase

58326113

Analogs

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Popular Name: (3R)-N-[[3,5-dimethyl-4-(2,2,2-trifluoroethoxy)phenyl]methyl]-N-methyl-tetrahydrofuran-3-carboxamide (3R)-N-[[3,5-dimethyl-4-(2,2,2-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.28	7.71	-11.25	0	4	0	39	345.361	6	↓ MOL2 SDF SMILES Flexibase

58326115

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[[3,5-dimethyl-4-(2,2,2-trifluoroethoxy)phenyl]methyl]-N-methyl-tetrahydrofuran-3-carboxamide (3S)-N-[[3,5-dimethyl-4-(2,2,2-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.28	7.79	-11.41	0	4	0	39	345.361	6	↓ MOL2 SDF SMILES Flexibase

59415759

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-[(3-cyanophenyl)methyl]-N-methyl-tetrahydrofuran-3-carboxamide (3R)-N-[(3-cyanophenyl)methyl]-N…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.28	5.99	-14.77	0	4	0	53	244.294	3	↓ MOL2 SDF SMILES Flexibase

59415762

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(3-cyanophenyl)methyl]-N-methyl-tetrahydrofuran-3-carboxamide (3S)-N-[(3-cyanophenyl)methyl]-N…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.28	6.07	-14.95	0	4	0	53	244.294	3	↓ MOL2 SDF SMILES Flexibase

63000690

Analogs

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Popular Name: (3R)-N-[(1S)-2-hydroxy-1-phenyl-ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1S)-2-hydroxy-1-phenyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.86	1.32	-8.74	2	4	0	59	235.283	4	↓ MOL2 SDF SMILES Flexibase

63000691

Analogs

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Popular Name: (3R)-N-[(1R)-2-hydroxy-1-phenyl-ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1R)-2-hydroxy-1-phenyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.86	1.32	-8.59	2	4	0	59	235.283	4	↓ MOL2 SDF SMILES Flexibase

63000692

Analogs

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Popular Name: (3S)-N-[(1S)-2-hydroxy-1-phenyl-ethyl]tetrahydrofuran-3-carboxamide (3S)-N-[(1S)-2-hydroxy-1-phenyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.86	1.32	-7.87	2	4	0	59	235.283	4	↓ MOL2 SDF SMILES Flexibase

63000693

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(1R)-2-hydroxy-1-phenyl-ethyl]tetrahydrofuran-3-carboxamide (3S)-N-[(1R)-2-hydroxy-1-phenyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.86	1.32	-8.01	2	4	0	59	235.283	4	↓ MOL2 SDF SMILES Flexibase

69464802

Analogs

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Popular Name: (3R)-N-[[4-isopropoxy-2-(trifluoromethyl)phenyl]methyl]tetrahydrofuran-3-carboxamide (3R)-N-[[4-isopropoxy-2-(trifluo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.92	5.91	-8.98	1	4	0	48	331.334	6	↓ MOL2 SDF SMILES Flexibase

69464805

Analogs

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Popular Name: (3S)-N-[[4-isopropoxy-2-(trifluoromethyl)phenyl]methyl]tetrahydrofuran-3-carboxamide (3S)-N-[[4-isopropoxy-2-(trifluo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.92	5.92	-8.95	1	4	0	48	331.334	6	↓ MOL2 SDF SMILES Flexibase

55042148

Analogs

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Popular Name: (3R)-N-allyl-N-(o-tolylmethyl)tetrahydrofuran-3-carboxamide (3R)-N-allyl-N-(o-tolylmethyl)te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.59	8.23	-9.2	0	3	0	30	259.349	5	↓ MOL2 SDF SMILES Flexibase

55042149

Analogs

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Popular Name: (3S)-N-allyl-N-(o-tolylmethyl)tetrahydrofuran-3-carboxamide (3S)-N-allyl-N-(o-tolylmethyl)te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.59	8.3	-7.71	0	3	0	30	259.349	5	↓ MOL2 SDF SMILES Flexibase

69702511

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	5.05	-13.1	1	5	0	65	313.3	5	↓ MOL2 SDF SMILES Flexibase

69702514

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	5.05	-12.98	1	5	0	65	313.3	5	↓ MOL2 SDF SMILES Flexibase

69702516

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	5.07	-12.1	1	5	0	65	313.3	5	↓ MOL2 SDF SMILES Flexibase

69702517

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	5.08	-12.2	1	5	0	65	313.3	5	↓ MOL2 SDF SMILES Flexibase

49340594

Analogs

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Popular Name: (3R)-N-[(2-hydroxy-5-nitro-phenyl)methyl]tetrahydrofuran-3-carboxamide (3R)-N-[(2-hydroxy-5-nitro-pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.18	1.52	-12.71	2	7	0	104	266.253	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	1.18	2.28	-35.29	1	7	-1	107	265.245	4	↓ MOL2 SDF SMILES Flexibase

49340595

Analogs

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Popular Name: (3S)-N-[(2-hydroxy-5-nitro-phenyl)methyl]tetrahydrofuran-3-carboxamide (3S)-N-[(2-hydroxy-5-nitro-pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.18	1.53	-12.51	2	7	0	104	266.253	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	1.18	2.29	-32.84	1	7	-1	107	265.245	4	↓ MOL2 SDF SMILES Flexibase

49340607

Analogs

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Popular Name: (3R)-N-[(3,4-dimethoxyphenyl)methyl]tetrahydrofuran-3-carboxamide (3R)-N-[(3,4-dimethoxyphenyl)met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.95	2.84	-11.56	1	5	0	57	265.309	5	↓ MOL2 SDF SMILES Flexibase

49340608

Analogs

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Popular Name: (3S)-N-[(3,4-dimethoxyphenyl)methyl]tetrahydrofuran-3-carboxamide (3S)-N-[(3,4-dimethoxyphenyl)met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.95	2.85	-10.91	1	5	0	57	265.309	5	↓ MOL2 SDF SMILES Flexibase

49340625

Analogs

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Popular Name: (3R)-N-[(4-chlorophenyl)methyl]tetrahydrofuran-3-carboxamide (3R)-N-[(4-chlorophenyl)methyl]t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	4.17	-8.18	1	3	0	38	239.702	3	↓ MOL2 SDF SMILES Flexibase

49340626

Analogs

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Popular Name: (3S)-N-[(4-chlorophenyl)methyl]tetrahydrofuran-3-carboxamide (3S)-N-[(4-chlorophenyl)methyl]t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	4.17	-7.47	1	3	0	38	239.702	3	↓ MOL2 SDF SMILES Flexibase

49340668

Analogs

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Popular Name: (3R)-N-[(1S)-1-(4-fluorophenyl)ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1S)-1-(4-fluorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.03	4.55	-9.16	1	3	0	38	237.274	3	↓ MOL2 SDF SMILES Flexibase

49340669

Analogs

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Popular Name: (3R)-N-[(1R)-1-(4-fluorophenyl)ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1R)-1-(4-fluorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.03	4.55	-9.41	1	3	0	38	237.274	3	↓ MOL2 SDF SMILES Flexibase

49340670

Analogs

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Popular Name: (3S)-N-[(1S)-1-(4-fluorophenyl)ethyl]tetrahydrofuran-3-carboxamide (3S)-N-[(1S)-1-(4-fluorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.03	4.56	-8.66	1	3	0	38	237.274	3	↓ MOL2 SDF SMILES Flexibase

49340671

Analogs

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Popular Name: (3S)-N-[(1R)-1-(4-fluorophenyl)ethyl]tetrahydrofuran-3-carboxamide (3S)-N-[(1R)-1-(4-fluorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.03	4.56	-8.45	1	3	0	38	237.274	3	↓ MOL2 SDF SMILES Flexibase

49340683

Analogs

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Popular Name: (3R)-N-[(1R)-1-(o-tolyl)ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1R)-1-(o-tolyl)ethyl]te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.26	4.97	-8.75	1	3	0	38	233.311	3	↓ MOL2 SDF SMILES Flexibase

49340684

Analogs

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Popular Name: (3R)-N-[(1S)-1-(o-tolyl)ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1S)-1-(o-tolyl)ethyl]te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.26	5.07	-8.64	1	3	0	38	233.311	3	↓ MOL2 SDF SMILES Flexibase

49340685

Analogs

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Popular Name: (3S)-N-[(1R)-1-(o-tolyl)ethyl]tetrahydrofuran-3-carboxamide (3S)-N-[(1R)-1-(o-tolyl)ethyl]te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.26	4.98	-7.79	1	3	0	38	233.311	3	↓ MOL2 SDF SMILES Flexibase

49340686

Analogs

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Popular Name: (3S)-N-[(1S)-1-(o-tolyl)ethyl]tetrahydrofuran-3-carboxamide (3S)-N-[(1S)-1-(o-tolyl)ethyl]te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.26	5.07	-7.96	1	3	0	38	233.311	3	↓ MOL2 SDF SMILES Flexibase

49340700

Analogs

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Popular Name: (3R)-N-[(4-fluorophenyl)methyl]tetrahydrofuran-3-carboxamide (3R)-N-[(4-fluorophenyl)methyl]t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.47	3.71	-8.67	1	3	0	38	223.247	3	↓ MOL2 SDF SMILES Flexibase

49340701

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(4-fluorophenyl)methyl]tetrahydrofuran-3-carboxamide (3S)-N-[(4-fluorophenyl)methyl]t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.47	3.72	-8.05	1	3	0	38	223.247	3	↓ MOL2 SDF SMILES Flexibase

49340728

Analogs

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Popular Name: (3R)-N-[(1R)-1-(2,5-dimethylphenyl)ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1R)-1-(2,5-dimethylphen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.69	5.71	-8.68	1	3	0	38	247.338	3	↓ MOL2 SDF SMILES Flexibase

49340729

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-[(1S)-1-(2,5-dimethylphenyl)ethyl]tetrahydrofuran-3-carboxamide (3R)-N-[(1S)-1-(2,5-dimethylphen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.69	5.66	-8.52	1	3	0	38	247.338	3	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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