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Analogs

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Popular Name: 5-amino-N-(1,3,4-thiadiazol-2-yl)-1H-indole-3-carboxamide 5-amino-N-(1,3,4-thiadiazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.75 2.06 -24.2 4 6 0 97 259.294 2 ↓

Analogs

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Popular Name: 1-ethyl-N-(1,3,4-thiadiazol-2-yl)indole-3-carboxamide 1-ethyl-N-(1,3,4-thiadiazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.14 6.8 -22.35 1 5 0 60 272.333 3 ↓
Hi High (pH 8-9.5) 2.21 5.23 -53.69 0 5 -1 66 271.325 3 ↓

Analogs

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Popular Name: 1-(cyanomethyl)-N-(1,3,4-thiadiazol-2-yl)indole-3-carboxamide 1-(cyanomethyl)-N-(1,3,4-thiadia…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.55 6.53 -30.07 1 6 0 84 283.316 3 ↓
Hi High (pH 8-9.5) 1.62 4.98 -57.16 0 6 -1 90 282.308 3 ↓

Analogs

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Popular Name: N-(5-isopropyl-1,3,4-thiadiazol-2-yl)-1H-indole-3-carboxamide N-(5-isopropyl-1,3,4-thiadiazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.47 6.3 -22.35 2 5 0 71 286.36 3 ↓
Hi High (pH 8-9.5) 2.53 4.73 -54.82 1 5 -1 77 285.352 3 ↓

Analogs

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Popular Name: 1-propyl-N-(1,3,4-thiadiazol-2-yl)indole-3-carboxamide 1-propyl-N-(1,3,4-thiadiazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.64 7.55 -21.88 1 5 0 60 286.36 4 ↓
Hi High (pH 8-9.5) 2.71 5.98 -53.26 0 5 -1 66 285.352 4 ↓

Analogs

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Popular Name: 1-allyl-N-(1,3,4-thiadiazol-2-yl)indole-3-carboxamide 1-allyl-N-(1,3,4-thiadiazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.41 7.34 -22.09 1 5 0 60 284.344 4 ↓
Hi High (pH 8-9.5) 2.48 5.79 -53.05 0 5 -1 66 283.336 4 ↓

Analogs

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Popular Name: 2-methyl-N-(1,3,4-thiadiazol-2-yl)-1H-indole-3-carboxamide 2-methyl-N-(1,3,4-thiadiazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.92 4.7 -17.17 2 5 0 71 258.306 2 ↓
Hi High (pH 8-9.5) 1.98 2.83 -55.72 1 5 -1 77 257.298 2 ↓

Parameters Provided:

ring.id = 215605
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 215605 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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