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Analogs

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Popular Name: N2-(cyclopentylmethyl)-3-methyl-pyridine-2,5-diamine N2-(cyclopentylmethyl)-3-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 5.14 -25.38 4 3 1 52 206.313 3 ↓
Mid Mid (pH 6-8) 2.71 4.79 -4.96 3 3 0 51 205.305 3 ↓

Analogs

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Popular Name: N-(cyclopentylmethyl)-3-fluoro-pyridin-2-amine N-(cyclopentylmethyl)-3-fluoro-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.79 6.24 -3.9 1 2 0 25 194.253 3 ↓
Lo Low (pH 4.5-6) 2.79 6.6 -30.84 2 2 1 26 195.261 3 ↓

Analogs

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Popular Name: N2-[(1S)-1-cyclopentylethyl]pyridine-2,3-diamine N2-[(1S)-1-cyclopentylethyl]pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.44 5.53 -26.03 4 3 1 52 206.313 3 ↓
Mid Mid (pH 6-8) 2.44 5.17 -4.43 3 3 0 51 205.305 3 ↓

Analogs

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Popular Name: N2-[(1R)-1-cyclopentylethyl]pyridine-2,3-diamine N2-[(1R)-1-cyclopentylethyl]pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.44 5.36 -26.13 4 3 1 52 206.313 3 ↓
Mid Mid (pH 6-8) 2.44 5.01 -4.49 3 3 0 51 205.305 3 ↓

Analogs

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Popular Name: N2-[(1S)-1-cyclopentylethyl]-3-methyl-pyridine-2,5-diamine N2-[(1S)-1-cyclopentylethyl]-3-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 5.89 -24.81 4 3 1 52 220.34 3 ↓
Mid Mid (pH 6-8) 3.04 5.55 -4.51 3 3 0 51 219.332 3 ↓

Analogs

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Popular Name: N2-[(1R)-1-cyclopentylethyl]-3-methyl-pyridine-2,5-diamine N2-[(1R)-1-cyclopentylethyl]-3-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 5.84 -24.65 4 3 1 52 220.34 3 ↓
Mid Mid (pH 6-8) 3.04 5.5 -4.59 3 3 0 51 219.332 3 ↓

Analogs

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Popular Name: N2-[(1S)-1-cyclopentylethyl]pyridine-2,5-diamine N2-[(1S)-1-cyclopentylethyl]pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.66 4.95 -26.01 4 3 1 52 206.313 3 ↓
Mid Mid (pH 6-8) 2.66 4.5 -4.18 3 3 0 51 205.305 3 ↓

Analogs

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Popular Name: N2-[(1R)-1-cyclopentylethyl]pyridine-2,5-diamine N2-[(1R)-1-cyclopentylethyl]pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.66 4.77 -26.06 4 3 1 52 206.313 3 ↓
Mid Mid (pH 6-8) 2.66 4.31 -4.15 3 3 0 51 205.305 3 ↓

Analogs

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Popular Name: 5-bromo-N2-[(1S)-1-cyclopentylethyl]pyridine-2,3-diamine 5-bromo-N2-[(1S)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.40 5.63 -3.84 3 3 0 51 284.201 3 ↓

Analogs

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Popular Name: 5-bromo-N2-[(1R)-1-cyclopentylethyl]pyridine-2,3-diamine 5-bromo-N2-[(1R)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.40 5.6 -3.87 3 3 0 51 284.201 3 ↓

Analogs

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Popular Name: N2-[(1S)-1-cyclopentylethyl]pyridine-2,4-diamine N2-[(1S)-1-cyclopentylethyl]pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.04 4.96 -26.46 4 3 1 52 206.313 3 ↓

Analogs

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Popular Name: N2-[(1R)-1-cyclopentylethyl]pyridine-2,4-diamine N2-[(1R)-1-cyclopentylethyl]pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.04 4.77 -26.52 4 3 1 52 206.313 3 ↓

Analogs

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Popular Name: 5-chloro-N-[(1S)-1-cyclopentylethyl]pyridin-2-amine 5-chloro-N-[(1S)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.86 6.96 -2.81 1 2 0 25 224.735 3 ↓

Analogs

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Popular Name: 5-chloro-N-[(1R)-1-cyclopentylethyl]pyridin-2-amine 5-chloro-N-[(1R)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.86 6.93 -2.83 1 2 0 25 224.735 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-4-methyl-pyridin-2-amine N-[(1S)-1-cyclopentylethyl]-4-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 7.75 -26.66 2 2 1 26 205.325 3 ↓
Hi High (pH 8-9.5) 3.41 7.29 -3.74 1 2 0 25 204.317 3 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-4-methyl-pyridin-2-amine N-[(1R)-1-cyclopentylethyl]-4-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 7.57 -26.74 2 2 1 26 205.325 3 ↓
Hi High (pH 8-9.5) 3.41 7.11 -3.73 1 2 0 25 204.317 3 ↓

Analogs

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Popular Name: 3,5-dichloro-N-[(1S)-1-cyclopentylethyl]pyridin-2-amine 3,5-dichloro-N-[(1S)-1-cyclopent…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.46 7.96 -1.72 1 2 0 25 259.18 3 ↓

Analogs

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Popular Name: 3,5-dichloro-N-[(1R)-1-cyclopentylethyl]pyridin-2-amine 3,5-dichloro-N-[(1R)-1-cyclopent…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.46 7.93 -1.77 1 2 0 25 259.18 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-3-methyl-pyridin-2-amine N-[(1S)-1-cyclopentylethyl]-3-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 8.13 -26.09 2 2 1 26 205.325 3 ↓
Mid Mid (pH 6-8) 3.41 7.79 -3.88 1 2 0 25 204.317 3 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-3-methyl-pyridin-2-amine N-[(1R)-1-cyclopentylethyl]-3-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 7.97 -26.23 2 2 1 26 205.325 3 ↓
Mid Mid (pH 6-8) 3.41 7.62 -3.9 1 2 0 25 204.317 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]pyridin-2-amine N-[(1S)-1-cyclopentylethyl]pyrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.01 7.09 -27.33 2 2 1 26 191.298 3 ↓
Mid Mid (pH 6-8) 3.01 6.63 -3.63 1 2 0 25 190.29 3 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]pyridin-2-amine N-[(1R)-1-cyclopentylethyl]pyrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.01 7.03 -27.37 2 2 1 26 191.298 3 ↓
Mid Mid (pH 6-8) 3.01 6.57 -3.68 1 2 0 25 190.29 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-methoxy-pyridin-2-amine N-[(1S)-1-cyclopentylethyl]-6-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 5.09 -4.4 1 3 0 34 220.316 4 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-methoxy-pyridin-2-amine N-[(1R)-1-cyclopentylethyl]-6-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 4.91 -4.34 1 3 0 34 220.316 4 ↓

Analogs

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Popular Name: 3-chloro-N-[(1S)-1-cyclopentylethyl]pyridin-2-amine 3-chloro-N-[(1S)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.64 7.59 -3.13 1 2 0 25 224.735 3 ↓

Analogs

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Popular Name: 3-chloro-N-[(1R)-1-cyclopentylethyl]pyridin-2-amine 3-chloro-N-[(1R)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.64 7.43 -3.12 1 2 0 25 224.735 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-methyl-pyridin-2-amine N-[(1S)-1-cyclopentylethyl]-6-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.06 7.67 -24.85 2 2 1 26 205.325 3 ↓
Hi High (pH 8-9.5) 3.06 7.24 -3.92 1 2 0 25 204.317 3 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-methyl-pyridin-2-amine N-[(1R)-1-cyclopentylethyl]-6-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.06 7.49 -24.9 2 2 1 26 205.325 3 ↓
Hi High (pH 8-9.5) 3.06 7.06 -3.94 1 2 0 25 204.317 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-3-fluoro-pyridin-2-amine N-[(1S)-1-cyclopentylethyl]-3-fl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 7.11 -3.76 1 2 0 25 208.28 3 ↓
Lo Low (pH 4.5-6) 3.12 7.45 -29.97 2 2 1 26 209.288 3 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-3-fluoro-pyridin-2-amine N-[(1R)-1-cyclopentylethyl]-3-fl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 6.95 -3.72 1 2 0 25 208.28 3 ↓
Lo Low (pH 4.5-6) 3.12 7.29 -30.04 2 2 1 26 209.288 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-5-methyl-pyridin-2-amine N-[(1S)-1-cyclopentylethyl]-5-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 7.73 -26.33 2 2 1 26 205.325 3 ↓
Mid Mid (pH 6-8) 3.46 7.26 -3.59 1 2 0 25 204.317 3 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-5-methyl-pyridin-2-amine N-[(1R)-1-cyclopentylethyl]-5-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 7.55 -26.4 2 2 1 26 205.325 3 ↓
Mid Mid (pH 6-8) 3.46 7.08 -3.57 1 2 0 25 204.317 3 ↓

Analogs

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Popular Name: 6-bromo-N-[(1S)-1-cyclopentylethyl]pyridin-2-amine 6-bromo-N-[(1S)-1-cyclopentyleth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.16 6.97 -4.17 1 2 0 25 269.186 3 ↓

Analogs

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Popular Name: 6-bromo-N-[(1R)-1-cyclopentylethyl]pyridin-2-amine 6-bromo-N-[(1R)-1-cyclopentyleth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.16 6.94 -4.14 1 2 0 25 269.186 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-fluoro-pyridin-2-amine N-[(1S)-1-cyclopentylethyl]-6-fl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.51 6.41 -5.22 1 2 0 25 208.28 3 ↓
Lo Low (pH 4.5-6) 3.51 6.89 -26.98 2 2 1 26 209.288 3 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-fluoro-pyridin-2-amine N-[(1R)-1-cyclopentylethyl]-6-fl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.51 6.39 -5.18 1 2 0 25 208.28 3 ↓
Lo Low (pH 4.5-6) 3.51 6.86 -26.85 2 2 1 26 209.288 3 ↓

Analogs

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Popular Name: 6-chloro-N-[(1S)-1-cyclopentylethyl]pyridin-2-amine 6-chloro-N-[(1S)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.03 6.89 -4.24 1 2 0 25 224.735 3 ↓

Analogs

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Popular Name: 6-chloro-N-[(1R)-1-cyclopentylethyl]pyridin-2-amine 6-chloro-N-[(1R)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.03 6.87 -4.26 1 2 0 25 224.735 3 ↓

Analogs

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Popular Name: 5-amino-2-[[(1S)-1-cyclopentylethyl]amino]pyridine-3-carboxamide 5-amino-2-[[(1S)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.41 1.92 -8.58 5 5 0 94 248.33 4 ↓
Lo Low (pH 4.5-6) 1.41 2.27 -31.68 6 5 1 95 249.338 4 ↓

Analogs

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Popular Name: 5-amino-2-[[(1R)-1-cyclopentylethyl]amino]pyridine-3-carboxamide 5-amino-2-[[(1R)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.41 1.9 -8.68 5 5 0 94 248.33 4 ↓
Lo Low (pH 4.5-6) 1.41 2.22 -31.71 6 5 1 95 249.338 4 ↓

Analogs

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Popular Name: N2-[(1S)-1-cyclopentylethyl]-6-propoxy-pyridine-2,5-diamine N2-[(1S)-1-cyclopentylethyl]-6-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 4.67 -4.36 3 4 0 60 263.385 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N2-[(1R)-1-cyclopentylethyl]-6-propoxy-pyridine-2,5-diamine N2-[(1R)-1-cyclopentylethyl]-6-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 4.77 -4.42 3 4 0 60 263.385 6 ↓

Analogs

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Popular Name: N2-[(1S)-1-cyclopentylethyl]-6-isobutoxy-pyridine-2,5-diamine N2-[(1S)-1-cyclopentylethyl]-6-i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.96 5.36 -4.21 3 4 0 60 277.412 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N2-[(1R)-1-cyclopentylethyl]-6-isobutoxy-pyridine-2,5-diamine N2-[(1R)-1-cyclopentylethyl]-6-i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.96 5.46 -4.19 3 4 0 60 277.412 6 ↓

Analogs

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Popular Name: 6-tert-butoxy-N2-[(1S)-1-cyclopentylethyl]pyridine-2,5-diamine 6-tert-butoxy-N2-[(1S)-1-cyclope…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.03 6.63 -3.51 3 4 0 60 277.412 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-tert-butoxy-N2-[(1R)-1-cyclopentylethyl]pyridine-2,5-diamine 6-tert-butoxy-N2-[(1R)-1-cyclope…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.03 6.58 -3.57 3 4 0 60 277.412 5 ↓

Analogs

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Popular Name: N2-[(1S)-1-cyclopentylethyl]-6-methoxy-pyridine-2,5-diamine N2-[(1S)-1-cyclopentylethyl]-6-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 2.93 -4.6 3 4 0 60 235.331 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N2-[(1R)-1-cyclopentylethyl]-6-methoxy-pyridine-2,5-diamine N2-[(1R)-1-cyclopentylethyl]-6-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 3.03 -4.68 3 4 0 60 235.331 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-amino-2-[[(1S)-1-cyclopentylethyl]amino]pyridine-3-carbonitrile 5-amino-2-[[(1S)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.34 5.17 -5.22 3 4 0 75 230.315 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-amino-2-[[(1R)-1-cyclopentylethyl]amino]pyridine-3-carbonitrile 5-amino-2-[[(1R)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.34 5.14 -5.23 3 4 0 75 230.315 3 ↓

Parameters Provided:

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filter.purchasability = annotated
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Structural Results Found: (before additional filtering)

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