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Popular Name: 5-(aminomethyl)-1-[(3R)-chroman-3-yl]-3H-imidazole-2-thione 5-(aminomethyl)-1-[(3R)-chroman-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.07 4.93 -72.34 4 4 1 58 262.358 2 ↓

Analogs

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Popular Name: 5-(aminomethyl)-1-[(3R)-6-hydroxychroman-3-yl]-3H-imidazole-2-thione 5-(aminomethyl)-1-[(3R)-6-hydrox…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.56 2.06 -75.63 5 5 1 78 278.357 2 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-chroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-chroman…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.87 5.7 -70.13 4 4 1 58 276.385 3 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-6-fluorochroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-6-fluor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.00 5.76 -71.46 4 4 1 58 294.375 3 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-6-methoxychroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-6-metho…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.90 4.97 -71.61 4 5 1 67 306.411 4 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-6-hydroxychroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-6-hydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.36 2.83 -73.11 5 5 1 78 292.384 3 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-6-nitrochroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-6-nitro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.80 6.36 -76.09 4 7 1 103 321.382 4 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-8-fluorochroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-8-fluor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.98 5.77 -71.58 4 4 1 58 294.375 3 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-8-methoxychroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-8-metho…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.68 5.67 -71.75 4 5 1 67 306.411 4 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-8-hydroxychroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-8-hydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.37 3.61 -70.61 5 5 1 78 292.384 3 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-8-nitrochroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-8-nitro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.78 7.15 -75.85 4 7 1 103 321.382 4 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-6,7-difluorochroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-6,7-dif…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.10 5.81 -73.19 4 4 1 58 312.365 3 ↓

Analogs

3948603
3948603

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Popular Name: 5-(2-aminoethyl)-1-[(3S)-6,8-difluorochroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3S)-6,8-dif…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.10 5.84 -73.17 4 4 1 58 312.365 3 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-6-chloro-8-methoxy-chroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-6-chlor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.31 6.17 -71.68 4 5 1 67 340.856 4 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-8-chloro-6-methoxy-chroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-8-chlor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.50 5.54 -71.38 4 5 1 67 340.856 4 ↓

Analogs

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Popular Name: 5-(2-aminoethyl)-1-[(3R)-6,7,8-trifluorochroman-3-yl]-3H-imidazole-2-thione 5-(2-aminoethyl)-1-[(3R)-6,7,8-t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.19 5.88 -74.64 4 4 1 58 330.355 3 ↓

Analogs

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Popular Name: 1-[(3R)-chroman-3-yl]-5-(2-methylaminoethyl)-3H-imidazole-2-thione 1-[(3R)-chroman-3-yl]-5-(2-methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.85 7.57 -65.11 3 4 1 47 290.412 4 ↓

Analogs

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Popular Name: 1-[(3R)-6-hydroxychroman-3-yl]-5-(2-methylaminoethyl)-3H-imidazole-2-thione 1-[(3R)-6-hydroxychroman-3-yl]-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.34 4.7 -67.99 4 5 1 67 306.411 4 ↓

Analogs

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Popular Name: 1-[(3R)-6,8-difluorochroman-3-yl]-5-(2-methylaminoethyl)-3H-imidazole-2-thione 1-[(3R)-6,8-difluorochroman-3-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.08 7.71 -66.79 3 4 1 47 326.392 4 ↓

Parameters Provided:

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