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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF
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Popular Name: 1-(4,7-dibenzyloxy-6-hydroxy-benzofuran-5-yl)ethanone 1-(4,7-dibenzyloxy-6-hydroxy-ben…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
KCNA1-1-E Voltage-gated Potassium Channel Subunit Kv1.1 (cluster #1 Of 1), Eukaryotic Eukaryotes 7000 0.25 Functional ≤ 10μM
KCNA2-1-E Voltage-gated Potassium Channel Subunit Kv1.2 (cluster #1 Of 1), Eukaryotic Eukaryotes 10000 0.24 Functional ≤ 10μM
KCNA3-1-E Voltage-gated Potassium Channel Subunit Kv1.3 (cluster #1 Of 2), Eukaryotic Eukaryotes 1200 0.29 Functional ≤ 10μM
KCNA5-1-E Voltage-gated Potassium Channel Subunit Kv1.5 (cluster #1 Of 1), Eukaryotic Eukaryotes 5000 0.26 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
KCNA1_HUMAN Q09470 Voltage-gated Potassium Channel Subunit Kv1.1, Human 7000 0.25 Functional ≤ 10μM
KCNA2_HUMAN P16389 Voltage-gated Potassium Channel Subunit Kv1.2, Human 10000 0.24 Functional ≤ 10μM
KCNA3_MOUSE P16390 Voltage-gated Potassium Channel Subunit Kv1.3, Mouse 1200 0.29 Functional ≤ 10μM
KCNA5_HUMAN P22460 Voltage-gated Potassium Channel Subunit Kv1.5, Human 5000 0.26 Functional ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.01 10.11 -12.46 1 5 0 69 388.419 7 ↓

Parameters Provided:

ring.id = 225531
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 225531 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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