UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

4542246
4542246
4542256
4542256
4542257
4542257

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Popular Name: N-(2-naphthyl)-1,2,3,4-tetrahydroacridine-9-carboxamide N-(2-naphthyl)-1,2,3,4-tetrahydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.64 -1.04 -10.64 1 3 0 41 352.437 2 ↓

Analogs

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Popular Name: 4-amino-N-(9-amino-5,6,7,8-tetrahydroacridin-2-yl)-3,5-diiodo-benzamide 4-amino-N-(9-amino-5,6,7,8-tetra…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.42 8.01 -29.43 6 5 1 95 585.207 2 ↓

Analogs

13704680
13704680

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Popular Name: (1R,5R,7S,9E)-9-ethylidene-3,8,8-trimethyl-N7-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]bicyclo (1R,5R,7S,9E)-9-ethylidene-3,8,8…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 8.35 15.41 -155.71 7 4 3 70 517.826 10 ↓
Hi High (pH 8-9.5) 8.35 14.39 -73.99 6 4 2 66 516.818 10 ↓
Mid Mid (pH 6-8) 8.35 15.18 -71.52 6 4 2 69 516.818 10 ↓

Analogs

13704683
13704683

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Popular Name: (1S,3S,5R,9E)-9-ethylidene-7-methyl-N3-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]bicyclo[3.3.1] (1S,3S,5R,9E)-9-ethylidene-7-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.53 15.4 -148.91 7 4 3 70 489.772 10 ↓
Mid Mid (pH 6-8) 7.53 15.17 -67.36 6 4 2 69 488.764 10 ↓

Analogs

13704683
13704683

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Popular Name: (1S,3R,5R,9E)-9-ethylidene-7-methyl-N3-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]bicyclo[3.3.1] (1S,3R,5R,9E)-9-ethylidene-7-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.53 14.43 -153.11 7 4 3 70 489.772 10 ↓
Mid Mid (pH 6-8) 7.53 14.2 -72.44 6 4 2 69 488.764 10 ↓

Analogs

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Popular Name: (8-bromo-5-fluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (8-bromo-5-fluoro-1,2,3,4-tetrah…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.69 6.39 -22.35 4 3 1 52 311.178 1 ↓
Mid Mid (pH 6-8) 3.69 6.01 -6.05 3 3 0 51 310.17 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (7-iodo-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-iodo-1,2,3,4-tetrahydroacridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.87 6.55 -25.45 4 3 1 52 340.188 1 ↓

Analogs

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Popular Name: (5-iodo-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-iodo-1,2,3,4-tetrahydroacridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.84 6.64 -22.37 4 3 1 52 340.188 1 ↓

Analogs

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Popular Name: 9-hydrazino-N,N-dimethyl-5,6,7,8-tetrahydroacridin-2-amine 9-hydrazino-N,N-dimethyl-5,6,7,8…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.89 5.86 -23.03 4 4 1 55 257.361 2 ↓

Analogs

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Popular Name: (6-chloro-5-fluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (6-chloro-5-fluoro-1,2,3,4-tetra…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 6.05 -25.49 4 3 1 52 266.727 1 ↓
Mid Mid (pH 6-8) 3.56 5.65 -9.64 3 3 0 51 265.719 1 ↓

Analogs

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Popular Name: (5-methoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-methoxy-1,2,3,4-tetrahydroacr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.82 4.89 -21.68 4 4 1 61 244.318 2 ↓

Analogs

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Popular Name: (6,8-difluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (6,8-difluoro-1,2,3,4-tetrahydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 5.66 -25.2 4 3 1 52 250.272 1 ↓
Hi High (pH 8-9.5) 3.04 5.29 -4.56 3 3 0 51 249.264 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (7-ethoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-ethoxy-1,2,3,4-tetrahydroacri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.22 5.67 -24.99 4 4 1 61 258.345 3 ↓

Analogs

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Popular Name: (5,7-dimethyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5,7-dimethyl-1,2,3,4-tetrahydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 6.86 -22.17 4 3 1 52 242.346 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (7-methyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-methyl-1,2,3,4-tetrahydroacri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 6.1 -22.91 4 3 1 52 228.319 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (8-chloro-5-fluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (8-chloro-5-fluoro-1,2,3,4-tetra…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 6.19 -22.02 4 3 1 52 266.727 1 ↓
Mid Mid (pH 6-8) 3.56 5.81 -6.96 3 3 0 51 265.719 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (7-ethyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-ethyl-1,2,3,4-tetrahydroacrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 6.89 -22.97 4 3 1 52 242.346 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-ethoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-ethoxy-1,2,3,4-tetrahydroacri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.19 5.78 -21.25 4 4 1 61 258.345 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-fluoro-8-methyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-fluoro-8-methyl-1,2,3,4-tetra…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 6.44 -22.2 4 3 1 52 246.309 1 ↓
Hi High (pH 8-9.5) 3.33 6.06 -8.81 3 3 0 51 245.301 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-ethyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-ethyl-1,2,3,4-tetrahydroacrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.68 6.95 -21.93 4 3 1 52 242.346 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (8-chloro-5,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (8-chloro-5,7-dimethoxy-1,2,3,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.43 4.91 -23.24 4 5 1 71 308.789 3 ↓
Hi High (pH 8-9.5) 3.43 4.43 -8.93 3 5 0 69 307.781 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (7-fluoro-5-methyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-fluoro-5-methyl-1,2,3,4-tetra…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 6.27 -25.21 4 3 1 52 246.309 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-methoxy-8-methyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-methoxy-8-methyl-1,2,3,4-tetr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.22 5.75 -21.1 4 4 1 61 258.345 2 ↓

Analogs

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Popular Name: (7-chloro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-chloro-1,2,3,4-tetrahydroacri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 5.95 -25.74 4 3 1 52 248.737 1 ↓

Analogs

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Popular Name: (8-chloro-5-methoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (8-chloro-5-methoxy-1,2,3,4-tetr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 5.56 -21.6 4 4 1 61 278.763 2 ↓
Hi High (pH 8-9.5) 3.45 5.14 -7.47 3 4 0 60 277.755 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-fluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-fluoro-1,2,3,4-tetrahydroacri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.92 5.54 -22.72 4 3 1 52 232.282 1 ↓
Hi High (pH 8-9.5) 2.92 5.16 -10.05 3 3 0 51 231.274 1 ↓

Analogs

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Popular Name: (5,8-difluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5,8-difluoro-1,2,3,4-tetrahydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 5.71 -22.36 4 3 1 52 250.272 1 ↓
Mid Mid (pH 6-8) 3.04 5.33 -7.01 3 3 0 51 249.264 1 ↓

Analogs

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Popular Name: (7-bromo-5-fluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-bromo-5-fluoro-1,2,3,4-tetrah…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.69 6.15 -24.28 4 3 1 52 311.178 1 ↓
Mid Mid (pH 6-8) 3.69 5.79 -7.04 3 3 0 51 310.17 1 ↓

Analogs

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Popular Name: (5-chloro-7-fluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-chloro-7-fluoro-1,2,3,4-tetra…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.58 6.07 -23.73 4 3 1 52 266.727 1 ↓
Mid Mid (pH 6-8) 2.58 5.77 -5.83 3 3 0 51 265.719 1 ↓

Analogs

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Popular Name: (6,8-dimethoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (6,8-dimethoxy-1,2,3,4-tetrahydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 4.55 -22.52 4 5 1 71 274.344 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (6,7-difluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (6,7-difluoro-1,2,3,4-tetrahydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.07 5.59 -28.36 4 3 1 52 250.272 1 ↓
Hi High (pH 8-9.5) 2.07 5.22 -5.97 3 3 0 51 249.264 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (6,7-dimethoxy-1,2,3,4-tetrahydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.43 4.69 -27.38 4 5 1 71 274.344 3 ↓

Analogs

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Popular Name: (6,8-dimethyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (6,8-dimethyl-1,2,3,4-tetrahydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 7.01 -22.55 4 3 1 52 242.346 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (7-chloro-5-fluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-chloro-5-fluoro-1,2,3,4-tetra…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 6.04 -24.12 4 3 1 52 266.727 1 ↓
Mid Mid (pH 6-8) 3.56 5.69 -6.99 3 3 0 51 265.719 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (8-fluoro-5-methyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (8-fluoro-5-methyl-1,2,3,4-tetra…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 6.38 -23.1 4 3 1 52 246.309 1 ↓
Hi High (pH 8-9.5) 3.50 6.35 -21.52 4 3 1 56 246.309 0 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5,8-dimethoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5,8-dimethoxy-1,2,3,4-tetrahydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 4.62 -20.79 4 5 1 71 274.344 3 ↓

Analogs

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Popular Name: (5-fluoro-7-methyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-fluoro-7-methyl-1,2,3,4-tetra…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 6.19 -22.4 4 3 1 52 246.309 1 ↓
Hi High (pH 8-9.5) 3.33 5.81 -9.95 3 3 0 51 245.301 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5,8-dimethyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5,8-dimethyl-1,2,3,4-tetrahydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 7.08 -22.13 4 3 1 52 242.346 1 ↓

Analogs

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Popular Name: (5-bromo-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-bromo-1,2,3,4-tetrahydroacrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.57 6.16 -22.53 4 3 1 52 293.188 1 ↓
Hi High (pH 8-9.5) 3.57 5.8 -8.08 3 3 0 51 292.18 1 ↓

Analogs

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Popular Name: (5,6-dimethyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5,6-dimethyl-1,2,3,4-tetrahydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 6.76 -22.08 4 3 1 52 242.346 1 ↓

Analogs

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Popular Name: (7-fluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-fluoro-1,2,3,4-tetrahydroacri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.98 5.51 -26.36 4 3 1 52 232.282 1 ↓

Analogs

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Popular Name: (5-chloro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-chloro-1,2,3,4-tetrahydroacri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.44 6.01 -22.15 4 3 1 52 248.737 1 ↓
Hi High (pH 8-9.5) 3.44 5.67 -8.21 3 3 0 51 247.729 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (7-isopropoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-isopropoxy-1,2,3,4-tetrahydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.58 6.29 -24.89 4 4 1 61 272.372 3 ↓

Analogs

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Popular Name: (5,6,7-trifluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5,6,7-trifluoro-1,2,3,4-tetrahy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.16 5.28 -9.1 3 3 0 51 267.254 1 ↓
Mid Mid (pH 6-8) 2.16 5.66 -27.7 4 3 1 52 268.262 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5,7-difluoro-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5,7-difluoro-1,2,3,4-tetrahydro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.07 5.61 -24.42 4 3 1 52 250.272 1 ↓
Mid Mid (pH 6-8) 2.07 5.25 -6.94 3 3 0 51 249.264 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5,7-dimethoxy-1,2,3,4-tetrahydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 4.19 -22.14 4 5 1 71 274.344 3 ↓

Analogs

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Popular Name: [7-(difluoromethoxy)-1,2,3,4-tetrahydroacridin-9-yl]hydrazine [7-(difluoromethoxy)-1,2,3,4-tet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.40 5.01 -26.4 4 4 1 61 280.298 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [5-(difluoromethoxy)-1,2,3,4-tetrahydroacridin-9-yl]hydrazine [5-(difluoromethoxy)-1,2,3,4-tet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.38 5.16 -24.62 4 4 1 61 280.298 3 ↓
Hi High (pH 8-9.5) 3.38 4.74 -10.26 3 4 0 60 279.29 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (7-methoxy-1,2,3,4-tetrahydroacr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 4.74 -25.12 4 4 1 61 244.318 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-methyl-1,2,3,4-tetrahydroacridin-9-yl)hydrazine (5-methyl-1,2,3,4-tetrahydroacri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 6.2 -22.22 4 3 1 52 228.319 1 ↓

Parameters Provided:

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Structural Results Found: (before additional filtering)

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