UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 2-(4-methoxybenzyl)-N-(4-methoxyphenyl)-1,3-thiazole-4-carboxamide 2-(4-methoxybenzyl)-N-(4-methoxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.80 6.51 -12.3 1 5 0 60 354.431 6 ↓

Analogs

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Popular Name: 2-(4-chlorobenzyl)-N-(4-methoxyphenyl)-1,3-thiazole-4-carboxamide 2-(4-chlorobenzyl)-N-(4-methoxyp…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.43 7.71 -11.92 1 4 0 51 358.85 5 ↓

Analogs

31488465
31488465
31538792
31538792

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Popular Name: 2-benzyl-N-(4-chlorophenyl)-1,3-thiazole-4-carboxamide 2-benzyl-N-(4-chlorophenyl)-1,3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.37 8.45 -8.76 1 3 0 42 328.824 4 ↓

Analogs

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Popular Name: N-(4-chlorophenyl)-2-(4-methoxybenzyl)-1,3-thiazole-4-carboxamide N-(4-chlorophenyl)-2-(4-methoxyb…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.43 7.74 -10.75 1 4 0 51 358.85 5 ↓

Analogs

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Popular Name: N-(3,5-dichlorophenyl)-2-(4-methoxybenzyl)-1,3-thiazole-4-carboxamide N-(3,5-dichlorophenyl)-2-(4-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.03 -1.26 -9.02 1 4 0 51 393.295 5 ↓

Analogs

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Popular Name: N-(4-fluorophenyl)-2-(4-methoxybenzyl)-1,3-thiazole-4-carboxamide N-(4-fluorophenyl)-2-(4-methoxyb…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.91 7.29 -11.18 1 4 0 51 342.395 5 ↓

Analogs

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Popular Name: 2-(4-methoxybenzyl)-N-phenyl-1,3-thiazole-4-carboxamide 2-(4-methoxybenzyl)-N-phenyl-1,3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.75 7.22 -11.97 1 4 0 51 324.405 5 ↓

Analogs

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Popular Name: 2-(4-methoxybenzyl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxamide 2-(4-methoxybenzyl)-N-[3-(triflu…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.62 1.22 -12.51 1 4 0 51 392.402 6 ↓

Analogs

31488465
31488465
31538792
31538792

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Popular Name: 2-(4-chlorobenzyl)-N-(3,5-dichlorophenyl)-1,3-thiazole-4-carboxamide 2-(4-chlorobenzyl)-N-(3,5-dichlo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.65 -1.42 -8.37 1 3 0 41 397.714 4 ↓

Analogs

31491029
31491029

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Popular Name: 2-(4-chlorobenzyl)-N-(4-fluorophenyl)-1,3-thiazole-4-carboxamide 2-(4-chlorobenzyl)-N-(4-fluoroph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.53 -0.39 -9.54 1 3 0 41 346.814 4 ↓

Analogs

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Popular Name: 2-(2-chloro-6-methyl-benzyl)-N-(4-chloro-3-nitro-phenyl)thiazole-4-carboxamide 2-(2-chloro-6-methyl-benzyl)-N-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.29 10.05 -15.2 1 6 0 88 422.293 5 ↓

Analogs

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Popular Name: 2-benzyl-N-(2-dimethylaminoethyl)-N-phenyl-thiazole-4-carboxamide 2-benzyl-N-(2-dimethylaminoethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.96 11.86 -47.73 1 4 1 38 366.51 7 ↓
Hi High (pH 8-9.5) 3.96 9.99 -9.1 0 4 0 36 365.502 7 ↓

Analogs

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Popular Name: 2-benzyl-N-[2-(methylsulfonylmethyl)phenyl]thiazole-4-carboxamide 2-benzyl-N-[2-(methylsulfonylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.01 6.57 -19.87 1 5 0 76 386.498 6 ↓

Analogs

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Popular Name: 2-benzyl-N-(4-hydroxyphenyl)thiazole-4-carboxamide 2-benzyl-N-(4-hydroxyphenyl)thia…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 5.07 -10.73 2 4 0 62 310.378 4 ↓

Parameters Provided:

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