UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 3-(2-fluorobenzyl)-5-(2-isopropoxy-3-methoxybenzylidene)imidazolidine-2,4-dione 3-(2-fluorobenzyl)-5-(2-isopropo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.08 9.48 -11 1 6 0 73 384.407 6 ↓

Analogs

39894918
39894918
39894939
39894939
39894952
39894952

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Popular Name: 5-[4-(diethylamino)benzylidene]-3-(4-methylbenzyl)-2,4-imidazolidinedione 5-[4-(diethylamino)benzylidene]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 11.14 -9.26 1 5 0 58 363.461 6 ↓

Analogs

686793
686793

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Popular Name: 5-(4-ethoxy-3-iodo-5-methoxybenzylidene)-3-(4-methylbenzyl)-2,4-imidazolidinedione 5-(4-ethoxy-3-iodo-5-methoxybenz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.08 10.75 -10.03 1 6 0 73 492.313 6 ↓

Analogs

686797
686797

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Popular Name: (5Z)-5-[(4-isopropoxyphenyl)methylene]-3-(p-tolylmethyl)imidazolidine-2,4-dione (5Z)-5-[(4-isopropoxyphenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.65 10.23 -8.4 1 5 0 64 350.418 5 ↓

Analogs

3652658
3652658
3659076
3659076

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Popular Name: (5E)-3-[(2-fluorophenyl)methyl]-5-[(3-hydroxy-4-methoxy-phenyl)methylene]imidazolidine-2,4-dione (5E)-3-[(2-fluorophenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.86 5.33 -13.56 2 6 0 84 342.326 4 ↓

Analogs

8722258
8722258

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Popular Name: (5E)-5-[(5-bromo-2,4-dimethoxy-phenyl)methylene]-3-[(4-chlorophenyl)methyl]imidazolidine-2,4-dione (5E)-5-[(5-bromo-2,4-dimethoxy-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.86 8.03 -10.21 1 6 0 73 451.704 5 ↓

Analogs

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Popular Name: (5Z)-5-[(3-chloro-4-sec-butoxy-phenyl)methylene]-3-[(4-nitrophenyl)methyl]imidazolidine-2,4-dione (5Z)-5-[(3-chloro-4-sec-butoxy-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.26 11.58 -12.92 1 8 0 110 429.86 7 ↓

Analogs

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Popular Name: (5Z)-5-[(3-chloro-4-sec-butoxy-phenyl)methylene]-3-[(4-nitrophenyl)methyl]imidazolidine-2,4-dione (5Z)-5-[(3-chloro-4-sec-butoxy-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.26 11.57 -11.82 1 8 0 110 429.86 7 ↓

Analogs

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Popular Name: (5Z)-5-[(3-allyl-5-ethoxy-4-hydroxy-phenyl)methylene]-3-[(4-fluorophenyl)methyl]imidazolidine-2,4-di (5Z)-5-[(3-allyl-5-ethoxy-4-hydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.26 8.35 -10.9 2 6 0 84 396.418 7 ↓
Ref Reference (pH 7) 3.26 8.86 -9.77 2 6 0 84 396.418 7 ↓

Analogs

1147324
1147324

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Popular Name: (5Z)-5-[(3-chloro-4-sec-butoxy-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4-dione (5Z)-5-[(3-chloro-4-sec-butoxy-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.42 10.92 -11.24 1 5 0 64 402.853 6 ↓

Analogs

1147324
1147324

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Popular Name: (5Z)-5-[(3-chloro-4-sec-butoxy-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4-dione (5Z)-5-[(3-chloro-4-sec-butoxy-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.42 10.91 -11.14 1 5 0 64 402.853 6 ↓

Analogs

3659356
3659356

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Popular Name: (5E)-5-[(3-bromo-4-ethoxy-5-methoxy-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4-di (5E)-5-[(3-bromo-4-ethoxy-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 9.11 -14.21 1 6 0 73 449.276 6 ↓

Analogs

3659310
3659310

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Popular Name: (5E)-5-[(3-chloro-4-methoxy-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4-dione (5E)-5-[(3-chloro-4-methoxy-phen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 8.03 -11.1 1 5 0 64 360.772 4 ↓

Analogs

3659317
3659317

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Popular Name: (5E)-3-[(2-fluorophenyl)methyl]-5-[(4-sec-butoxyphenyl)methylene]imidazolidine-2,4-dione (5E)-3-[(2-fluorophenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.81 9.84 -11.6 1 5 0 64 368.408 6 ↓

Analogs

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Popular Name: (5E)-5-[(3-allyl-5-ethoxy-4-prop-2-ynoxy-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2 (5E)-5-[(3-allyl-5-ethoxy-4-prop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.65 11.84 -14.01 1 6 0 73 434.467 9 ↓

Analogs

3659342
3659342

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Popular Name: (5E)-5-[(3-bromo-4-methoxy-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4-dione (5E)-5-[(3-bromo-4-methoxy-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.31 8.15 -11.22 1 5 0 64 405.223 4 ↓

Analogs

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Popular Name: 5-(3-chloro-4-hydroxybenzylidene)-3-(2-fluorobenzyl)-2,4-imidazolidinedione 5-(3-chloro-4-hydroxybenzylidene…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.90 5.89 -11.54 2 5 0 75 346.745 3 ↓
Ref Reference (pH 7) 2.90 6.42 -10.52 2 5 0 75 346.745 3 ↓
Hi High (pH 8-9.5) 2.90 7.13 -41.39 1 5 -1 78 345.737 3 ↓

Analogs

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Popular Name: 5-[3-ethoxy-4-(2-propynyloxy)benzylidene]-3-(2-fluorobenzyl)-2,4-imidazolidinedione 5-[3-ethoxy-4-(2-propynyloxy)ben…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 9.78 -14.85 1 6 0 73 394.402 7 ↓

Analogs

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Popular Name: 5-(3-allyl-5-ethoxy-4-hydroxybenzylidene)-3-(2-fluorobenzyl)-2,4-imidazolidinedione 5-(3-allyl-5-ethoxy-4-hydroxyben…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 8.29 -12.81 2 6 0 84 396.418 7 ↓
Ref Reference (pH 7) 3.21 8.8 -11.84 2 6 0 84 396.418 7 ↓

Analogs

663530
663530

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Popular Name: (5E)-5-[(3-chloro-4,5-dimethoxy-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4-dione (5E)-5-[(3-chloro-4,5-dimethoxy-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.97 8.04 -14.42 1 6 0 73 390.798 5 ↓

Analogs

3652596
3652596

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Popular Name: (5E)-5-[(4-ethoxy-5-isopropyl-2-methyl-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4 (5E)-5-[(4-ethoxy-5-isopropyl-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.29 10.99 -11.23 1 5 0 64 396.462 6 ↓

Analogs

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Popular Name: (5Z)-5-[(5-chloro-2-ethoxy-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4-dione (5Z)-5-[(5-chloro-2-ethoxy-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 9.48 -9.46 1 5 0 64 374.799 5 ↓

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.76 10.06 -14.05 1 7 0 90 398.39 8 ↓

Analogs

3652915
3652915

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Popular Name: (5E)-5-[(2-bromo-4-ethoxy-5-methoxy-phenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4-di (5E)-5-[(2-bromo-4-ethoxy-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 8.87 -11.18 1 6 0 73 449.276 6 ↓

Analogs

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Popular Name: (5Z)-5-[(2,5-dimethoxyphenyl)methylene]-3-[(2-fluorophenyl)methyl]imidazolidine-2,4-dione (5Z)-5-[(2,5-dimethoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.56 7.33 -10.95 1 6 0 73 356.353 5 ↓

Analogs

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Popular Name: 2-[4-[(E)-[1-[(2-fluorophenyl)methyl]-2,5-dioxo-imidazolidin-4-ylidene]methyl]phenoxy]acetic 2-[4-[(E)-[1-[(2-fluorophenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.82 8.12 -54.7 1 7 -1 104 369.328 6 ↓

Analogs

3652859
3652859

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Popular Name: (5E)-3-[(2-fluorophenyl)methyl]-5-[(2,4,5-trimethoxyphenyl)methylene]imidazolidine-2,4-dione (5E)-3-[(2-fluorophenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.15 6.76 -13.76 1 7 0 83 386.379 6 ↓

Analogs

4526116
4526116

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Popular Name: (5E)-3-[(4-chlorophenyl)methyl]-5-[(5-isopropyl-4-methoxy-2-methyl-phenyl)methylene]imidazolidine-2, (5E)-3-[(4-chlorophenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.48 10.57 -9.02 1 5 0 64 398.89 5 ↓

Analogs

2784812
2784812

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Popular Name: (5E)-3-[(4-chlorophenyl)methyl]-5-[(4-methyl-3-nitro-phenyl)methylene]imidazolidine-2,4-dione (5E)-3-[(4-chlorophenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 9.87 -16.16 1 7 0 101 371.78 4 ↓

Analogs

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Popular Name: 2-[4-[(E)-[1-[(4-bromophenyl)methyl]-2,5-dioxo-imidazolidin-4-ylidene]methyl]-2-ethoxy-phenoxy]aceti 2-[4-[(E)-[1-[(4-bromophenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 9.41 -58.21 1 8 -1 113 474.287 8 ↓

Analogs

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Popular Name: (5E)-5-[(3-bromo-5-ethoxy-4-hydroxy-phenyl)methylene]-3-[(4-chlorophenyl)methyl]imidazolidine-2,4-di (5E)-5-[(3-bromo-5-ethoxy-4-hydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.76 7.43 -11.49 2 6 0 84 451.704 5 ↓
Ref Reference (pH 7) 3.76 7.94 -9.92 2 6 0 84 451.704 5 ↓
Hi High (pH 8-9.5) 3.76 8.35 -48.36 1 6 -1 87 450.696 5 ↓

Analogs

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Popular Name: (5E)-3-[(4-chlorophenyl)methyl]-5-[(3-methoxy-4-prop-2-ynoxy-phenyl)methylene]imidazolidine-2,4-dion (5E)-3-[(4-chlorophenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.89 9.38 -13.25 1 6 0 73 396.83 6 ↓

Analogs

638919
638919
660779
660779

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.63 11.92 -15.1 1 8 0 100 476.888 10 ↓

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.07 11.81 -13.23 1 7 0 90 467.28 8 ↓

Analogs

661012
661012

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Popular Name: (5E)-5-[(2-isopropoxy-3-methoxy-phenyl)methylene]-3-(p-tolylmethyl)imidazolidine-2,4-dione (5E)-5-[(2-isopropoxy-3-methoxy-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 9.56 -9.26 1 6 0 73 380.444 6 ↓

Analogs

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Popular Name: (5E)-5-[(3-allyl-4,5-diethoxy-phenyl)methylene]-3-[(4-fluorophenyl)methyl]imidazolidine-2,4-dione (5E)-5-[(3-allyl-4,5-diethoxy-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.91 11.37 -11.09 1 6 0 73 424.472 9 ↓

Analogs

638919
638919
660779
660779

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.25 11.01 -15.23 1 8 0 100 462.861 9 ↓

Analogs

1163595
1163595

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Popular Name: (5Z)-5-[(4-ethoxy-5-isopropyl-2-methyl-phenyl)methylene]-3-[(4-fluorophenyl)methyl]imidazolidine-2,4 (5Z)-5-[(4-ethoxy-5-isopropyl-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.34 11.55 -7.88 1 5 0 64 396.462 6 ↓

Analogs

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Popular Name: (5Z)-5-[(5-bromo-2-hydroxy-3-methoxy-phenyl)methylene]-3-[(4-fluorophenyl)methyl]imidazolidine-2,4-d (5Z)-5-[(5-bromo-2-hydroxy-3-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 6.04 -10.91 2 6 0 84 421.222 4 ↓
Ref Reference (pH 7) 2.87 6.55 -9.18 2 6 0 84 421.222 4 ↓
Hi High (pH 8-9.5) 2.87 6.96 -41.13 1 6 -1 87 420.214 4 ↓

Analogs

1161676
1161676

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Popular Name: (5Z)-5-[(3-chloro-5-methoxy-4-sec-butoxy-phenyl)methylene]-3-[(4-fluorophenyl)methyl]imidazolidine-2 (5Z)-5-[(3-chloro-5-methoxy-4-se…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.26 10.98 -10.05 1 6 0 73 432.879 7 ↓

Analogs

1161676
1161676

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Popular Name: (5Z)-5-[(3-chloro-5-methoxy-4-sec-butoxy-phenyl)methylene]-3-[(4-fluorophenyl)methyl]imidazolidine-2 (5Z)-5-[(3-chloro-5-methoxy-4-se…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.26 10.9 -10.07 1 6 0 73 432.879 7 ↓

Analogs

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Popular Name: (2-bromo-4-{[1-(4-fluorobenzyl)-2,5-dioxoimidazolidin-4-ylidene]methyl}phenoxy)acetic acid (2-bromo-4-{[1-(4-fluorobenzyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.60 8.81 -54.98 1 7 -1 104 448.224 6 ↓

Analogs

14010026
14010026

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Popular Name: (5Z)-3-(4-chlorobenzyl)-5-(4-methyl-3-nitro-benzylidene)hydantoin (5Z)-3-(4-chlorobenzyl)-5-(4-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 1.12 -13.61 1 7 0 100 371.78 4 ↓

Analogs

2784932
2784932

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Popular Name: (5Z)-5-(4-allyloxybenzylidene)-3-(4-chlorobenzyl)hydantoin (5Z)-5-(4-allyloxybenzylidene)-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.78 0.91 -8.09 1 5 0 64 368.82 6 ↓

Analogs

2784931
2784931

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Popular Name: (5E)-5-(4-allyloxybenzylidene)-3-(4-chlorobenzyl)hydantoin (5E)-5-(4-allyloxybenzylidene)-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.78 0.24 -9.29 1 5 0 64 368.82 6 ↓

Analogs

33153876
33153876

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Popular Name: (5E)-5-(5-bromo-2-ethoxy-benzylidene)-3-(4-chlorobenzyl)hydantoin (5E)-5-(5-bromo-2-ethoxy-benzyli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.25 -0.92 -7.89 1 5 0 64 435.705 5 ↓

Analogs

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Popular Name: (5Z)-3-(4-chlorobenzyl)-5-(3-ethoxy-2-hydroxy-benzylidene)hydantoin (5Z)-3-(4-chlorobenzyl)-5-(3-eth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.00 7.31 -9.46 2 6 0 84 372.808 5 ↓

Analogs

8816297
8816297

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Popular Name: (5Z)-5-(3-bromo-4-propargyloxy-benzylidene)-3-(4-chlorobenzyl)hydantoin (5Z)-5-(3-bromo-4-propargyloxy-b…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.03 10.59 -12.64 1 5 0 64 445.7 5 ↓

Analogs

26465049
26465049

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Popular Name: (5Z)-5-(4-allyloxy-2-bromo-5-methoxy-benzylidene)-3-(4-chlorobenzyl)hydantoin (5Z)-5-(4-allyloxy-2-bromo-5-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.11 10.45 -8.69 1 6 0 73 477.742 7 ↓

Analogs

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Popular Name: (5Z)-3-(4-bromobenzyl)-5-(3-nitrobenzylidene)hydantoin (5Z)-3-(4-bromobenzyl)-5-(3-nitr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.14 0.31 -14.27 1 7 0 100 402.204 4 ↓

Parameters Provided:

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