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Popular Name: (2R)-2-amino-N-cyclopropyl-2-phenyl-propanamide (2R)-2-amino-N-cyclopropyl-2-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.22 2.86 -6.85 3 3 0 55 204.273 3 ↓
Mid Mid (pH 6-8) 1.22 3.17 -51.03 4 3 1 57 205.281 3 ↓

Analogs

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Popular Name: (2S)-2-amino-N-cyclopropyl-2-phenyl-propanamide (2S)-2-amino-N-cyclopropyl-2-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.22 2.93 -7.88 3 3 0 55 204.273 3 ↓
Mid Mid (pH 6-8) 1.22 3.17 -50.97 4 3 1 57 205.281 3 ↓

Analogs

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Popular Name: (2R)-2-amino-N-cyclopropyl-N-ethyl-2-phenyl-propanamide (2R)-2-amino-N-cyclopropyl-N-eth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 4.9 -5.8 2 3 0 46 232.327 4 ↓
Mid Mid (pH 6-8) 1.84 5.1 -44.27 3 3 1 48 233.335 4 ↓

Analogs

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Popular Name: (2S)-2-amino-N-cyclopropyl-N-ethyl-2-phenyl-propanamide (2S)-2-amino-N-cyclopropyl-N-eth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 5.11 -7.92 2 3 0 46 232.327 4 ↓
Mid Mid (pH 6-8) 1.84 5.39 -43.46 3 3 1 48 233.335 4 ↓

Analogs

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Popular Name: (2R)-2-amino-N-cyclopropyl-N-methyl-2-phenyl-propanamide (2R)-2-amino-N-cyclopropyl-N-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.47 4.33 -6.16 2 3 0 46 218.3 3 ↓
Mid Mid (pH 6-8) 1.47 4.52 -44.76 3 3 1 48 219.308 3 ↓

Analogs

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Popular Name: (2S)-2-amino-N-cyclopropyl-N-methyl-2-phenyl-propanamide (2S)-2-amino-N-cyclopropyl-N-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.47 4.35 -8.38 2 3 0 46 218.3 3 ↓
Mid Mid (pH 6-8) 1.47 4.72 -47.98 3 3 1 48 219.308 3 ↓

Analogs

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Popular Name: (2R)-2-amino-N-cyclopropyl-2-phenyl-N-propyl-propanamide (2R)-2-amino-N-cyclopropyl-2-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 6.27 -5.48 2 3 0 46 246.354 5 ↓
Mid Mid (pH 6-8) 2.35 5.86 -44.4 3 3 1 48 247.362 5 ↓

Analogs

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Popular Name: (2S)-2-amino-N-cyclopropyl-2-phenyl-N-propyl-propanamide (2S)-2-amino-N-cyclopropyl-2-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 6.84 -6.42 2 3 0 46 246.354 5 ↓
Mid Mid (pH 6-8) 2.35 6.14 -43.69 3 3 1 48 247.362 5 ↓

Analogs

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Popular Name: (2R)-2-amino-N-cyclopropyl-N-(2-hydroxyethyl)-2-phenyl-propanamide (2R)-2-amino-N-cyclopropyl-N-(2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.84 2.63 -7.27 3 4 0 67 248.326 5 ↓
Mid Mid (pH 6-8) 0.84 2.22 -42.96 4 4 1 68 249.334 5 ↓

Analogs

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Popular Name: (2S)-2-amino-N-cyclopropyl-N-(2-hydroxyethyl)-2-phenyl-propanamide (2S)-2-amino-N-cyclopropyl-N-(2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.84 2.21 -6.75 3 4 0 67 248.326 5 ↓
Mid Mid (pH 6-8) 0.84 2.49 -43.99 4 4 1 68 249.334 5 ↓

Analogs

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Popular Name: (2R)-2-amino-N-cyclopropyl-N-isobutyl-2-phenyl-propanamide (2R)-2-amino-N-cyclopropyl-N-iso…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.59 5.85 -4.18 2 3 0 46 260.381 5 ↓
Mid Mid (pH 6-8) 2.59 6.98 -42.66 3 3 1 48 261.389 5 ↓

Analogs

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Popular Name: (2S)-2-amino-N-cyclopropyl-N-isobutyl-2-phenyl-propanamide (2S)-2-amino-N-cyclopropyl-N-iso…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.59 7.71 -6.62 2 3 0 46 260.381 5 ↓
Mid Mid (pH 6-8) 2.59 7.14 -44.97 3 3 1 48 261.389 5 ↓

Analogs

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Popular Name: (2R)-2-amino-N-cyclopropyl-N-isopentyl-2-phenyl-propanamide (2R)-2-amino-N-cyclopropyl-N-iso…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 7.63 -6.25 2 3 0 46 274.408 6 ↓
Mid Mid (pH 6-8) 3.12 7.85 -40.92 3 3 1 48 275.416 6 ↓

Analogs

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Popular Name: (2S)-2-amino-N-cyclopropyl-N-isopentyl-2-phenyl-propanamide (2S)-2-amino-N-cyclopropyl-N-iso…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 7.84 -6.47 2 3 0 46 274.408 6 ↓
Mid Mid (pH 6-8) 3.12 8.06 -43.02 3 3 1 48 275.416 6 ↓

Analogs

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Popular Name: (2R)-2-amino-N-butyl-N-cyclopropyl-2-phenyl-propanamide (2R)-2-amino-N-butyl-N-cycloprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 7.05 -5.41 2 3 0 46 260.381 6 ↓
Mid Mid (pH 6-8) 2.91 7.26 -43.18 3 3 1 48 261.389 6 ↓

Analogs

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Popular Name: (2S)-2-amino-N-butyl-N-cyclopropyl-2-phenyl-propanamide (2S)-2-amino-N-butyl-N-cycloprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 7.63 -6.41 2 3 0 46 260.381 6 ↓
Mid Mid (pH 6-8) 2.91 7.49 -45.52 3 3 1 48 261.389 6 ↓

Analogs

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Popular Name: (2R)-2-amino-N-cyclopropyl-N-(2-methoxyethyl)-2-phenyl-propanamide (2R)-2-amino-N-cyclopropyl-N-(2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.45 4.46 -4.93 2 4 0 56 262.353 6 ↓
Mid Mid (pH 6-8) 1.45 4.62 -42.08 3 4 1 57 263.361 6 ↓

Analogs

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Popular Name: (2S)-2-amino-N-cyclopropyl-N-(2-methoxyethyl)-2-phenyl-propanamide (2S)-2-amino-N-cyclopropyl-N-(2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.45 4.55 -7.21 2 4 0 56 262.353 6 ↓
Mid Mid (pH 6-8) 1.45 4.9 -44.07 3 4 1 57 263.361 6 ↓

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 6.17 -9.49 2 5 0 73 290.363 7 ↓
Mid Mid (pH 6-8) 1.71 6.35 -51.32 3 5 1 74 291.371 7 ↓

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 6.4 -11.14 2 5 0 73 290.363 7 ↓
Mid Mid (pH 6-8) 1.71 6.71 -43.11 3 5 1 74 291.371 7 ↓

Analogs

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Popular Name: (2R)-2-amino-N-(2-cyanoethyl)-N-cyclopropyl-2-phenyl-propanamide (2R)-2-amino-N-(2-cyanoethyl)-N-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.93 5.62 -8.87 2 4 0 70 257.337 5 ↓
Mid Mid (pH 6-8) 0.93 5.78 -53.75 3 4 1 72 258.345 5 ↓

Analogs

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Popular Name: (2S)-2-amino-N-(2-cyanoethyl)-N-cyclopropyl-2-phenyl-propanamide (2S)-2-amino-N-(2-cyanoethyl)-N-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.93 5.75 -10.35 2 4 0 70 257.337 5 ↓
Mid Mid (pH 6-8) 0.93 6.11 -51.49 3 4 1 72 258.345 5 ↓

Analogs

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Popular Name: 3-[[(2R)-2-amino-2-phenyl-propanoyl]-cyclopropyl-amino]propanoic 3-[[(2R)-2-amino-2-phenyl-propan…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.98 6.29 -52.87 2 5 -1 86 275.328 6 ↓
Mid Mid (pH 6-8) 0.98 5.95 -74.59 3 5 0 88 276.336 6 ↓

Analogs

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Popular Name: 3-[[(2S)-2-amino-2-phenyl-propanoyl]-cyclopropyl-amino]propanoic 3-[[(2S)-2-amino-2-phenyl-propan…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.98 5.84 -52.24 2 5 -1 86 275.328 6 ↓
Mid Mid (pH 6-8) 0.98 6.27 -78.07 3 5 0 88 276.336 6 ↓

Analogs

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Popular Name: 2-[[(2R)-2-amino-2-phenyl-propanoyl]-cyclopropyl-amino]acetic 2-[[(2R)-2-amino-2-phenyl-propan…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.20 5.47 -50.44 2 5 -1 86 261.301 5 ↓
Mid Mid (pH 6-8) -0.20 5.63 -61.24 3 5 0 88 262.309 5 ↓

Analogs

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Popular Name: 2-[[(2S)-2-amino-2-phenyl-propanoyl]-cyclopropyl-amino]acetic 2-[[(2S)-2-amino-2-phenyl-propan…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.20 5.58 -56.64 2 5 -1 86 261.301 5 ↓
Mid Mid (pH 6-8) -0.20 5.71 -78.7 3 5 0 88 262.309 5 ↓

Analogs

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Popular Name: (2R)-2-amino-N-cyclopropyl-2-phenyl-N-(2,2,2-trifluoroethyl)propanamide (2R)-2-amino-N-cyclopropyl-2-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 5.9 -7.85 2 3 0 46 286.297 5 ↓
Mid Mid (pH 6-8) 2.39 5.55 -44.53 3 3 1 48 287.305 5 ↓

Analogs

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Popular Name: (2S)-2-amino-N-cyclopropyl-2-phenyl-N-(2,2,2-trifluoroethyl)propanamide (2S)-2-amino-N-cyclopropyl-2-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 5.65 -8.09 2 3 0 46 286.297 5 ↓
Mid Mid (pH 6-8) 2.39 5.86 -50.62 3 3 1 48 287.305 5 ↓

Analogs

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Popular Name: (2R)-2-amino-N-[(1S)-2,2-dimethylcyclopropyl]-2-phenyl-propanamide (2R)-2-amino-N-[(1S)-2,2-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.79 4.28 -7.74 3 3 0 55 232.327 3 ↓
Mid Mid (pH 6-8) 1.79 4.52 -51.42 4 3 1 57 233.335 3 ↓

Analogs

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Popular Name: (2R)-2-amino-N-[(1R)-2,2-dimethylcyclopropyl]-2-phenyl-propanamide (2R)-2-amino-N-[(1R)-2,2-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.79 4.28 -7.73 3 3 0 55 232.327 3 ↓
Mid Mid (pH 6-8) 1.79 4.52 -51.47 4 3 1 57 233.335 3 ↓

Analogs

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Popular Name: (2S)-2-amino-N-[(1S)-2,2-dimethylcyclopropyl]-2-phenyl-propanamide (2S)-2-amino-N-[(1S)-2,2-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.79 4.22 -6.77 3 3 0 55 232.327 3 ↓
Mid Mid (pH 6-8) 1.79 4.52 -51.42 4 3 1 57 233.335 3 ↓

Analogs

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Popular Name: (2S)-2-amino-N-[(1R)-2,2-dimethylcyclopropyl]-2-phenyl-propanamide (2S)-2-amino-N-[(1R)-2,2-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.79 4.22 -6.76 3 3 0 55 232.327 3 ↓
Mid Mid (pH 6-8) 1.79 4.52 -51.36 4 3 1 57 233.335 3 ↓

Analogs

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Popular Name: (2R)-2-amino-N-[(1S,2R)-2-methylcyclopropyl]-2-phenyl-propanamide (2R)-2-amino-N-[(1S,2R)-2-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 3.71 -6.72 3 3 0 55 218.3 3 ↓
Mid Mid (pH 6-8) 1.83 4.01 -51.08 4 3 1 57 219.308 3 ↓

Analogs

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Popular Name: (2R)-2-amino-N-[(1S,2S)-2-methylcyclopropyl]-2-phenyl-propanamide (2R)-2-amino-N-[(1S,2S)-2-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 3.53 -6.81 3 3 0 55 218.3 3 ↓
Mid Mid (pH 6-8) 1.83 3.84 -51.28 4 3 1 57 219.308 3 ↓

Analogs

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Popular Name: (2R)-2-amino-N-[(1R,2R)-2-methylcyclopropyl]-2-phenyl-propanamide (2R)-2-amino-N-[(1R,2R)-2-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 3.53 -6.81 3 3 0 55 218.3 3 ↓
Mid Mid (pH 6-8) 1.83 3.84 -51.37 4 3 1 57 219.308 3 ↓

Analogs

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Popular Name: (2R)-2-amino-N-[(1R,2S)-2-methylcyclopropyl]-2-phenyl-propanamide (2R)-2-amino-N-[(1R,2S)-2-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 3.71 -6.76 3 3 0 55 218.3 3 ↓
Mid Mid (pH 6-8) 1.83 4.01 -51.11 4 3 1 57 219.308 3 ↓

Analogs

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Popular Name: (2S)-2-chloro-N-cyclopropyl-2-(4-propoxyphenyl)acetamide (2S)-2-chloro-N-cyclopropyl-2-(4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 6.62 -9.35 1 3 0 38 267.756 6 ↓

Analogs

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Popular Name: (2R)-2-chloro-N-cyclopropyl-2-(4-propoxyphenyl)acetamide (2R)-2-chloro-N-cyclopropyl-2-(4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 6.62 -9.34 1 3 0 38 267.756 6 ↓

Analogs

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Popular Name: (2S)-2-chloro-N-cyclopropyl-2-(3-propoxyphenyl)acetamide (2S)-2-chloro-N-cyclopropyl-2-(3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.88 6.61 -7.78 1 3 0 38 267.756 6 ↓

Analogs

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Popular Name: (2R)-2-chloro-N-cyclopropyl-2-(3-propoxyphenyl)acetamide (2R)-2-chloro-N-cyclopropyl-2-(3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.88 6.6 -7.74 1 3 0 38 267.756 6 ↓

Analogs

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Popular Name: 2-(3-aminophenyl)-N-cyclopropyl-N-ethyl-acetamide 2-(3-aminophenyl)-N-cyclopropyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.26 5.47 -9.62 2 3 0 46 218.3 4 ↓

Analogs

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Popular Name: 2-(3-aminophenyl)-N-cyclopropyl-N-methyl-acetamide 2-(3-aminophenyl)-N-cyclopropyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.88 4.75 -10.08 2 3 0 46 204.273 3 ↓

Analogs

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Popular Name: 2-(3-aminophenyl)-N-cyclopropyl-N-propyl-acetamide 2-(3-aminophenyl)-N-cyclopropyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.76 6.33 -9.14 2 3 0 46 232.327 5 ↓

Analogs

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Popular Name: 2-(3-aminophenyl)-N-cyclopropyl-N-(2-hydroxyethyl)acetamide 2-(3-aminophenyl)-N-cyclopropyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.25 2.63 -9.07 3 4 0 67 234.299 5 ↓

Analogs

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Popular Name: 2-(3-aminophenyl)-N-cyclopropyl-N-isopentyl-acetamide 2-(3-aminophenyl)-N-cyclopropyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.54 7.61 -9.07 2 3 0 46 260.381 6 ↓

Analogs

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Popular Name: 2-(3-aminophenyl)-N-butyl-N-cyclopropyl-acetamide 2-(3-aminophenyl)-N-butyl-N-cycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 7.11 -9.16 2 3 0 46 246.354 6 ↓

Analogs

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Popular Name: 2-(3-aminophenyl)-N-cyclopropyl-N-(2-methoxyethyl)acetamide 2-(3-aminophenyl)-N-cyclopropyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.87 5.43 -11.1 2 4 0 56 248.326 6 ↓

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.12 6.86 -12.93 2 5 0 73 276.336 7 ↓

Analogs

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Popular Name: 2-(3-aminophenyl)-N-(2-cyanoethyl)-N-cyclopropyl-acetamide 2-(3-aminophenyl)-N-(2-cyanoethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.34 6.13 -13.01 2 4 0 70 243.31 5 ↓

Analogs

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Popular Name: 2-(3-aminophenyl)-N-cyclopropyl-N-(2,2,2-trifluoroethyl)acetamide 2-(3-aminophenyl)-N-cyclopropyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.81 5.99 -9.72 2 3 0 46 272.27 5 ↓

Parameters Provided:

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SQL Query Was

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