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Analogs

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Popular Name: 2-methyl-5-(piperidin-4-yl)pyridine 2-methyl-5-(piperidin-4-yl)pyridine

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.56 4.71 -43.07 2 2 1 29 177.271 1 ↓
Lo Low (pH 4.5-6) 0.56 5.15 -87.73 3 2 2 31 178.279 1 ↓

Analogs

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Popular Name: 1-methyl-4-(6-methyl-3-pyridyl)piperidin-4-ol 1-methyl-4-(6-methyl-3-pyridyl)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.58 3.91 -38.64 2 3 1 38 207.297 1 ↓
Hi High (pH 8-9.5) 0.58 1.53 -5.56 1 3 0 36 206.289 1 ↓

Analogs

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Popular Name: 1-ethyl-4-(6-methyl-3-pyridyl)piperidin-4-ol 1-ethyl-4-(6-methyl-3-pyridyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.96 4.57 -37.41 2 3 1 38 221.324 2 ↓
Hi High (pH 8-9.5) 0.96 2.33 -5.4 1 3 0 36 220.316 2 ↓

Analogs

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Popular Name: 4-(6-methyl-3-pyridyl)-1-propyl-piperidin-4-ol 4-(6-methyl-3-pyridyl)-1-propyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 5.31 -38.13 2 3 1 38 235.351 3 ↓
Hi High (pH 8-9.5) 1.46 3.09 -5.31 1 3 0 36 234.343 3 ↓

Analogs

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Popular Name: 1-isopropyl-4-(6-methyl-3-pyridyl)piperidin-4-ol 1-isopropyl-4-(6-methyl-3-pyridy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.25 5.09 -35.93 2 3 1 38 235.351 2 ↓
Hi High (pH 8-9.5) 1.25 2.9 -5.3 1 3 0 36 234.343 2 ↓

Analogs

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Popular Name: 4-(6-methyl-3-pyridyl)piperidin-4-ol 4-(6-methyl-3-pyridyl)piperidin-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.01 1.68 -43.2 3 3 1 50 193.27 1 ↓

Analogs

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Popular Name: 3-(4-methyl-4-piperidyl)pyridine 3-(4-methyl-4-piperidyl)pyridine

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.13 4.25 -43.31 2 2 1 29 177.271 1 ↓
Lo Low (pH 4.5-6) 1.13 4.7 -86.63 3 2 2 31 178.279 1 ↓

Analogs

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Popular Name: 4-(2-amino-3-pyridyl)-1-methyl-piperidin-4-ol 4-(2-amino-3-pyridyl)-1-methyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.30 2.45 -39.24 4 4 1 64 208.285 1 ↓
Hi High (pH 8-9.5) 0.30 0.07 -4.71 3 4 0 62 207.277 1 ↓
Lo Low (pH 4.5-6) 0.30 2.93 -84.64 5 4 2 65 209.293 1 ↓

Analogs

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Popular Name: 4-(4-amino-3-pyridyl)-1-methyl-piperidin-4-ol 4-(4-amino-3-pyridyl)-1-methyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.06 2.04 -83.34 5 4 2 65 209.293 1 ↓
Hi High (pH 8-9.5) -0.06 -0.33 -31.86 4 4 1 64 208.285 1 ↓
Hi High (pH 8-9.5) -0.06 1.57 -40.72 4 4 1 64 208.285 1 ↓

Analogs

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Popular Name: 4-(2-amino-3-pyridyl)-1-ethyl-piperidin-4-ol 4-(2-amino-3-pyridyl)-1-ethyl-pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.68 3.11 -37.93 4 4 1 64 222.312 2 ↓
Hi High (pH 8-9.5) 0.68 0.88 -4.56 3 4 0 62 221.304 2 ↓
Lo Low (pH 4.5-6) 0.68 3.59 -84.11 5 4 2 65 223.32 2 ↓

Analogs

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Popular Name: 4-(4-amino-3-pyridyl)-1-ethyl-piperidin-4-ol 4-(4-amino-3-pyridyl)-1-ethyl-pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.32 2.7 -82.84 5 4 2 65 223.32 2 ↓
Hi High (pH 8-9.5) 0.32 0.48 -31.69 4 4 1 64 222.312 2 ↓
Hi High (pH 8-9.5) 0.32 2.23 -39.39 4 4 1 64 222.312 2 ↓

Analogs

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Popular Name: 4-(2-amino-3-pyridyl)piperidin-4-ol 4-(2-amino-3-pyridyl)piperidin-4-ol

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.29 0.23 -44.15 5 4 1 76 194.258 1 ↓
Lo Low (pH 4.5-6) -0.29 0.7 -88.84 6 4 2 77 195.266 1 ↓

Analogs

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Popular Name: 4-(4-amino-3-pyridyl)piperidin-4-ol 4-(4-amino-3-pyridyl)piperidin-4-ol

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.66 -0.19 -87.32 6 4 2 77 195.266 1 ↓
Hi High (pH 8-9.5) -0.66 -0.64 -45.63 5 4 1 76 194.258 1 ↓

Analogs

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Popular Name: 4-(2-amino-4-methyl-3-pyridyl)-1-methyl-piperidin-4-ol 4-(2-amino-4-methyl-3-pyridyl)-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.68 3.18 -40.69 4 4 1 64 222.312 1 ↓
Hi High (pH 8-9.5) 0.68 0.78 -4.25 3 4 0 62 221.304 1 ↓
Mid Mid (pH 6-8) 0.68 3.64 -80.53 5 4 2 65 223.32 1 ↓

Analogs

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Popular Name: 4-(2-amino-4-methyl-3-pyridyl)piperidin-4-ol 4-(2-amino-4-methyl-3-pyridyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.08 0.93 -48.43 5 4 1 76 208.285 1 ↓
Mid Mid (pH 6-8) 0.08 1.37 -86.21 6 4 2 77 209.293 1 ↓

Analogs

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Popular Name: 4-(2-amino-5-methyl-3-pyridyl)-1-methyl-piperidin-4-ol 4-(2-amino-5-methyl-3-pyridyl)-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.73 3.1 -39.39 4 4 1 64 222.312 1 ↓
Hi High (pH 8-9.5) 0.73 0.71 -4.58 3 4 0 62 221.304 1 ↓
Mid Mid (pH 6-8) 0.73 3.57 -84.57 5 4 2 65 223.32 1 ↓

Analogs

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Popular Name: 4-(2-amino-5-methyl-3-pyridyl)piperidin-4-ol 4-(2-amino-5-methyl-3-pyridyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.14 0.86 -44.22 5 4 1 76 208.285 1 ↓
Mid Mid (pH 6-8) 0.14 1.34 -88.78 6 4 2 77 209.293 1 ↓

Analogs

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Popular Name: 4-(2-amino-5-chloro-3-pyridyl)-1-methyl-piperidin-4-ol 4-(2-amino-5-chloro-3-pyridyl)-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.12 2.94 -40.68 4 4 1 64 242.73 1 ↓
Hi High (pH 8-9.5) 1.12 0.56 -3.8 3 4 0 62 241.722 1 ↓

Analogs

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Popular Name: 4-(2-amino-5-chloro-3-pyridyl)piperidin-4-ol 4-(2-amino-5-chloro-3-pyridyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.53 0.72 -45.8 5 4 1 76 228.703 1 ↓

Analogs

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Popular Name: 4-(2-amino-3-pyridyl)-1-propyl-piperidin-4-ol 4-(2-amino-3-pyridyl)-1-propyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.18 3.86 -38.67 4 4 1 64 236.339 3 ↓
Hi High (pH 8-9.5) 1.18 1.63 -4.42 3 4 0 62 235.331 3 ↓
Lo Low (pH 4.5-6) 1.18 4.33 -85.51 5 4 2 65 237.347 3 ↓

Analogs

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Popular Name: 4-(4-amino-3-pyridyl)-1-propyl-piperidin-4-ol 4-(4-amino-3-pyridyl)-1-propyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.82 3.44 -84.18 5 4 2 65 237.347 3 ↓
Hi High (pH 8-9.5) 0.82 2.98 -40.03 4 4 1 64 236.339 3 ↓
Hi High (pH 8-9.5) 0.82 1.23 -31.64 4 4 1 64 236.339 3 ↓

Analogs

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Popular Name: 4-(2-amino-3-pyridyl)-1-isopropyl-piperidin-4-ol 4-(2-amino-3-pyridyl)-1-isopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.97 3.64 -36.29 4 4 1 64 236.339 2 ↓
Hi High (pH 8-9.5) 0.97 1.43 -4.43 3 4 0 62 235.331 2 ↓
Lo Low (pH 4.5-6) 0.97 4.11 -83.21 5 4 2 65 237.347 2 ↓

Analogs

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Popular Name: 4-(4-amino-3-pyridyl)-1-isopropyl-piperidin-4-ol 4-(4-amino-3-pyridyl)-1-isopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.61 3.23 -81.97 5 4 2 65 237.347 2 ↓
Hi High (pH 8-9.5) 0.61 1.04 -31.58 4 4 1 64 236.339 2 ↓
Hi High (pH 8-9.5) 0.61 2.76 -37.65 4 4 1 64 236.339 2 ↓

Analogs

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Popular Name: 4-(5-fluoro-3-pyridyl)-1-methyl-piperidin-4-ol 4-(5-fluoro-3-pyridyl)-1-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.84 3.36 -40.58 2 3 1 38 211.26 1 ↓

Analogs

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Popular Name: 1-ethyl-4-(5-fluoro-3-pyridyl)piperidin-4-ol 1-ethyl-4-(5-fluoro-3-pyridyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.22 4.02 -39.37 2 3 1 38 225.287 2 ↓

Analogs

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Popular Name: 4-(5-fluoro-3-pyridyl)-1-propyl-piperidin-4-ol 4-(5-fluoro-3-pyridyl)-1-propyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.72 4.77 -40.16 2 3 1 38 239.314 3 ↓

Analogs

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Popular Name: 4-(5-fluoro-3-pyridyl)-1-isopropyl-piperidin-4-ol 4-(5-fluoro-3-pyridyl)-1-isoprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 4.55 -37.94 2 3 1 38 239.314 2 ↓

Parameters Provided:

ring.id = 316178
filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 316178 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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