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ZINC Item

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6728679

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(benzo[1,3]dioxol-5-ylmethylsulfamoyl)-N,2-dimethyl-benzamide 5-(benzo[1,3]dioxol-5-ylmethylsu…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.86	-6.56	-16.68	2	7	0	93	362.407	5	↓ MOL2 SDF SMILES Flexibase

6729102

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(1,3-benzodioxol-5-ylmethyl)-5-ethyl-2-methoxybenzenesulfonamide N-(1,3-benzodioxol-5-ylmethyl)-5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.19	-4.01	-14.18	1	6	0	73	349.408	6	↓ MOL2 SDF SMILES Flexibase

10514263

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(benzo[1,3]dioxol-5-ylmethyl)-N-ethyl-3,5-difluoro-benzenesulfonamide N-(benzo[1,3]dioxol-5-ylmethyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.17	-1.48	-14.18	0	5	0	55	355.362	5	↓ MOL2 SDF SMILES Flexibase

10514330

Analogs

22278990

Draw Identity 99% 90% 80% 70%

Popular Name: N-(benzo[1,3]dioxol-5-ylmethyl)-3,5-difluoro-N-methyl-benzenesulfonamide N-(benzo[1,3]dioxol-5-ylmethyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	-1.77	-13.81	0	5	0	55	341.335	4	↓ MOL2 SDF SMILES Flexibase

13252571

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4-chloro-benzoic 3-[[(1R)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.37	4.01	-52.64	1	7	-1	105	382.801	5	↓ MOL2 SDF SMILES Flexibase

13252573

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4-chloro-benzoic 3-[[(1S)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.37	4.03	-52.47	1	7	-1	105	382.801	5	↓ MOL2 SDF SMILES Flexibase

13252575

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-2-chloro-benzoic 5-[[(1R)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.03	3.8	-55.57	1	7	-1	105	382.801	5	↓ MOL2 SDF SMILES Flexibase

13252577

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-2-chloro-benzoic 5-[[(1S)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.03	3.88	-56.86	1	7	-1	105	382.801	5	↓ MOL2 SDF SMILES Flexibase

13252579

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]benzoic 3-[[(1R)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.74	3.4	-57.13	1	7	-1	105	348.356	5	↓ MOL2 SDF SMILES Flexibase

13252581

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]benzoic 3-[[(1S)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.74	3.47	-57.71	1	7	-1	105	348.356	5	↓ MOL2 SDF SMILES Flexibase

13252583

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (E)-3-[3-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4,5-dimethoxy-phenyl]prop-2-enoic (E)-3-[3-[[(1S)-1-(1,3-benzodiox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.60	4.7	-57.25	1	9	-1	123	434.446	8	↓ MOL2 SDF SMILES Flexibase

13252585

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (E)-3-[3-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4,5-dimethoxy-phenyl]prop-2-enoic (E)-3-[3-[[(1R)-1-(1,3-benzodiox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.60	4.51	-54.95	1	9	-1	123	434.446	8	↓ MOL2 SDF SMILES Flexibase

13252587

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-2-bromo-benzoic 5-[[(1R)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.16	3.89	-54.79	1	7	-1	105	427.252	5	↓ MOL2 SDF SMILES Flexibase

13252589

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-2-bromo-benzoic 5-[[(1S)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.16	3.97	-56.07	1	7	-1	105	427.252	5	↓ MOL2 SDF SMILES Flexibase

13252591

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (E)-3-[4-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]phenyl]prop-2-enoic (E)-3-[4-[[(1R)-1-(1,3-benzodiox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.83	4.64	-55.44	1	7	-1	105	374.394	6	↓ MOL2 SDF SMILES Flexibase

13252593

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (E)-3-[4-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]phenyl]prop-2-enoic (E)-3-[4-[[(1S)-1-(1,3-benzodiox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.83	4.71	-55.83	1	7	-1	105	374.394	6	↓ MOL2 SDF SMILES Flexibase

13252595

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-2-fluoro-benzoic 5-[[(1R)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.52	3.44	-58.64	1	7	-1	105	366.346	5	↓ MOL2 SDF SMILES Flexibase

13252597

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-2-fluoro-benzoic 5-[[(1S)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.52	3.51	-60.05	1	7	-1	105	366.346	5	↓ MOL2 SDF SMILES Flexibase

13252599

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4-bromo-benzoic 3-[[(1R)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.50	4.18	-52.49	1	7	-1	105	427.252	5	↓ MOL2 SDF SMILES Flexibase

13252601

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4-bromo-benzoic 3-[[(1S)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.50	4.27	-51.95	1	7	-1	105	427.252	5	↓ MOL2 SDF SMILES Flexibase

13252603

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]benzoic 4-[[(1R)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	3.41	-53.27	1	7	-1	105	348.356	5	↓ MOL2 SDF SMILES Flexibase

13252605

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]benzoic 4-[[(1S)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	3.49	-54.54	1	7	-1	105	348.356	5	↓ MOL2 SDF SMILES Flexibase

13252607

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[4-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]phenyl]propanoic 3-[4-[[(1R)-1-(1,3-benzodioxol-5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	5.03	-53.24	1	7	-1	105	376.41	7	↓ MOL2 SDF SMILES Flexibase

13252609

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[4-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]phenyl]propanoic 3-[4-[[(1S)-1-(1,3-benzodioxol-5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	5.1	-53.42	1	7	-1	105	376.41	7	↓ MOL2 SDF SMILES Flexibase

13252611

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4,5-dimethyl-benzoic 3-[[(1R)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.52	4.74	-62.4	1	7	-1	105	376.41	5	↓ MOL2 SDF SMILES Flexibase

13252613

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4,5-dimethyl-benzoic 3-[[(1S)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.52	4.87	-60.98	1	7	-1	105	376.41	5	↓ MOL2 SDF SMILES Flexibase

13252615

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4-methyl-benzoic 3-[[(1R)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.14	4.23	-61.28	1	7	-1	105	362.383	5	↓ MOL2 SDF SMILES Flexibase

13252617

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]sulfamoyl]-4-methyl-benzoic 3-[[(1S)-1-(1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.14	4.42	-59.57	1	7	-1	105	362.383	5	↓ MOL2 SDF SMILES Flexibase

58315320

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(1,3-benzodioxol-5-ylmethyl)-N-ethyl-2-methoxy-5-nitro-benzenesulfonamide N-(1,3-benzodioxol-5-ylmethyl)-N…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.86	6.52	-20.02	0	9	0	111	394.405	7	↓ MOL2 SDF SMILES Flexibase

14242232

Analogs

34948539

Draw Identity 99% 90% 80% 70%

Popular Name: N-(1,3-benzodioxol-5-ylmethyl)-2,5-dichloro-N-methyl-benzenesulfonamide N-(1,3-benzodioxol-5-ylmethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.82	5.94	-11.08	0	5	0	56	374.245	4	↓ MOL2 SDF SMILES Flexibase

14254143

Analogs

14254146
17072266
17072267

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-(1,3-benzodioxol-5-yl)ethyl]-4-tert-butyl-benzenesulfonamide N-[(1R)-1-(1,3-benzodioxol-5-yl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.56	6.11	-12.01	1	5	0	65	361.463	5	↓ MOL2 SDF SMILES Flexibase

14254146

Analogs

17072266
17072267
14254143

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]-4-tert-butyl-benzenesulfonamide N-[(1S)-1-(1,3-benzodioxol-5-yl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.56	6.19	-11.21	1	5	0	65	361.463	5	↓ MOL2 SDF SMILES Flexibase

69822886

Analogs

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Popular Name: N-(1,3-benzodioxol-5-ylmethyl)-N-ethyl-3-methyl-benzenesulfonamide N-(1,3-benzodioxol-5-ylmethyl)-N…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.34	6.58	-14.59	0	5	0	56	333.409	5	↓ MOL2 SDF SMILES Flexibase

69822900

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Popular Name: N-(1,3-benzodioxol-5-ylmethyl)-N-ethyl-2-methoxy-benzenesulfonamide N-(1,3-benzodioxol-5-ylmethyl)-N…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.92	5.8	-16.44	0	6	0	65	349.408	6	↓ MOL2 SDF SMILES Flexibase

69822968

Analogs

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Popular Name: N-(1,3-benzodioxol-5-ylmethyl)-N,3-dimethyl-benzenesulfonamide N-(1,3-benzodioxol-5-ylmethyl)-N…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.96	5.7	-12.28	0	5	0	56	319.382	4	↓ MOL2 SDF SMILES Flexibase

69822984

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(1,3-benzodioxol-5-ylmethyl)-2-methoxy-N-methyl-benzenesulfonamide N-(1,3-benzodioxol-5-ylmethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.55	4.92	-16.94	0	6	0	65	335.381	5	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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