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Analogs

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Popular Name: 6-(Cyclohexyloxy)-5-methylpyridin-3-amine 6-(Cyclohexyloxy)-5-methylpyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.03 3.61 -5.27 2 3 0 48 206.289 2 ↓

Analogs

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Popular Name: 5-methyl-6-(4-methylcyclohexoxy)pyridin-3-amine 5-methyl-6-(4-methylcyclohexoxy)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 4.29 -4.85 2 3 0 48 220.316 2 ↓

Analogs

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Popular Name: 6-[(1S,2R)-2-ethylcyclohexoxy]-5-methyl-pyridin-3-amine 6-[(1S,2R)-2-ethylcyclohexoxy]-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.77 4.99 -4.61 2 3 0 48 234.343 3 ↓

Analogs

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Popular Name: 6-[(1S,2S)-2-ethylcyclohexoxy]-5-methyl-pyridin-3-amine 6-[(1S,2S)-2-ethylcyclohexoxy]-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.77 4.91 -5.02 2 3 0 48 234.343 3 ↓

Analogs

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Popular Name: 6-[(1R,2R)-2-ethylcyclohexoxy]-5-methyl-pyridin-3-amine 6-[(1R,2R)-2-ethylcyclohexoxy]-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.77 4.91 -5 2 3 0 48 234.343 3 ↓

Analogs

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Popular Name: 6-[(1R,2S)-2-ethylcyclohexoxy]-5-methyl-pyridin-3-amine 6-[(1R,2S)-2-ethylcyclohexoxy]-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.77 4.99 -4.61 2 3 0 48 234.343 3 ↓

Analogs

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Popular Name: 5-methyl-6-[(1R,2S)-2-methylcyclohexoxy]pyridin-3-amine 5-methyl-6-[(1R,2S)-2-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.27 4.34 -4.75 2 3 0 48 220.316 2 ↓

Analogs

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Popular Name: 5-methyl-6-[(1S,2S)-2-methylcyclohexoxy]pyridin-3-amine 5-methyl-6-[(1S,2S)-2-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.27 4.26 -5.05 2 3 0 48 220.316 2 ↓

Analogs

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Popular Name: 5-methyl-6-[(1R,2R)-2-methylcyclohexoxy]pyridin-3-amine 5-methyl-6-[(1R,2R)-2-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.27 4.26 -5.07 2 3 0 48 220.316 2 ↓

Analogs

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Popular Name: 5-methyl-6-[(1S,2R)-2-methylcyclohexoxy]pyridin-3-amine 5-methyl-6-[(1S,2R)-2-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.27 4.34 -4.74 2 3 0 48 220.316 2 ↓

Analogs

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Popular Name: 5-methyl-6-[(1R,3S)-3-methylcyclohexoxy]pyridin-3-amine 5-methyl-6-[(1R,3S)-3-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 4.22 -5.12 2 3 0 48 220.316 2 ↓

Analogs

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Popular Name: 5-methyl-6-[(1S,3S)-3-methylcyclohexoxy]pyridin-3-amine 5-methyl-6-[(1S,3S)-3-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 4.3 -4.8 2 3 0 48 220.316 2 ↓

Analogs

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Popular Name: 5-methyl-6-[(1R,3R)-3-methylcyclohexoxy]pyridin-3-amine 5-methyl-6-[(1R,3R)-3-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 4.3 -4.8 2 3 0 48 220.316 2 ↓

Analogs

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Popular Name: 5-methyl-6-[(1S,3R)-3-methylcyclohexoxy]pyridin-3-amine 5-methyl-6-[(1S,3R)-3-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 4.22 -5.12 2 3 0 48 220.316 2 ↓

Analogs

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Popular Name: 2-(4-methylcyclohexoxy)pyridine-4-carboxamidine 2-(4-methylcyclohexoxy)pyridine-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.11 3.56 -37.81 4 4 1 74 234.323 3 ↓

Analogs

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Popular Name: 6-(cyclohexoxy)pyridine-3-carboxamidine 6-(cyclohexoxy)pyridine-3-carbox…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.39 2.83 -38.45 4 4 1 74 220.296 3 ↓

Analogs

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Popular Name: 2-[(1S,2R)-2-ethylcyclohexoxy]pyridine-4-carboxylic 2-[(1S,2R)-2-ethylcyclohexoxy]py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 6.07 -47.53 0 4 -1 62 248.302 4 ↓

Analogs

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Popular Name: 2-[(1S,2S)-2-ethylcyclohexoxy]pyridine-4-carboxylic 2-[(1S,2S)-2-ethylcyclohexoxy]py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 5.95 -46.98 0 4 -1 62 248.302 4 ↓

Analogs

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Popular Name: 2-[(1R,2R)-2-ethylcyclohexoxy]pyridine-4-carboxylic 2-[(1R,2R)-2-ethylcyclohexoxy]py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 5.94 -47 0 4 -1 62 248.302 4 ↓

Analogs

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Popular Name: 2-[(1R,2S)-2-ethylcyclohexoxy]pyridine-4-carboxylic 2-[(1R,2S)-2-ethylcyclohexoxy]py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 6.06 -47.5 0 4 -1 62 248.302 4 ↓

Analogs

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Popular Name: 5-chloro-6-[(1S,2R)-2-ethylcyclohexoxy]pyridine-3-carboxylic 5-chloro-6-[(1S,2R)-2-ethylcyclo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.93 6.62 -42.24 0 4 -1 62 282.747 4 ↓

Analogs

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Popular Name: 5-chloro-6-[(1S,2S)-2-ethylcyclohexoxy]pyridine-3-carboxylic 5-chloro-6-[(1S,2S)-2-ethylcyclo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.93 6.51 -41.88 0 4 -1 62 282.747 4 ↓

Analogs

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Popular Name: 5-chloro-6-[(1R,2R)-2-ethylcyclohexoxy]pyridine-3-carboxylic 5-chloro-6-[(1R,2R)-2-ethylcyclo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.93 6.51 -41.86 0 4 -1 62 282.747 4 ↓

Analogs

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Popular Name: 5-chloro-6-[(1R,2S)-2-ethylcyclohexoxy]pyridine-3-carboxylic 5-chloro-6-[(1R,2S)-2-ethylcyclo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.93 6.61 -42.21 0 4 -1 62 282.747 4 ↓

Analogs

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Popular Name: 6-[(1R,2R,5R)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-3-carboxylic 6-[(1R,2R,5R)-2-isopropyl-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.33 8.1 -44.49 0 4 -1 62 276.356 4 ↓

Analogs

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Popular Name: 6-[(1R,2R,5S)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-3-carboxylic 6-[(1R,2R,5S)-2-isopropyl-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.33 8.01 -44.34 0 4 -1 62 276.356 4 ↓

Analogs

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Popular Name: 6-[(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-3-carboxylic 6-[(1R,2S,5R)-2-isopropyl-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.33 7.85 -44.32 0 4 -1 62 276.356 4 ↓

Analogs

22146789
22146789
22146794
22146794
22146798
22146798

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Popular Name: 6-[(1R,2S,5S)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-3-carboxylic 6-[(1R,2S,5S)-2-isopropyl-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.33 7.64 -44.34 0 4 -1 62 276.356 4 ↓

Analogs

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Popular Name: 2-[(1R,2R,5R)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-4-carboxylic 2-[(1R,2R,5R)-2-isopropyl-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.61 8.11 -46.62 0 4 -1 62 276.356 4 ↓

Analogs

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Popular Name: 2-[(1R,2R,5S)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-4-carboxylic 2-[(1R,2R,5S)-2-isopropyl-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.61 8.01 -46.94 0 4 -1 62 276.356 4 ↓

Analogs

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Popular Name: 2-[(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-4-carboxylic 2-[(1R,2S,5R)-2-isopropyl-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.61 7.85 -46.5 0 4 -1 62 276.356 4 ↓

Analogs

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Popular Name: 2-[(1R,2S,5S)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-4-carboxylic 2-[(1R,2S,5S)-2-isopropyl-5-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.61 7.65 -46.57 0 4 -1 62 276.356 4 ↓

Analogs

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Popular Name: 3-chloro-6-[(1R,2R,5R)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-2-carboxylic 3-chloro-6-[(1R,2R,5R)-2-isoprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.41 8.53 -50.28 0 4 -1 62 310.801 4 ↓

Analogs

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Popular Name: 3-chloro-6-[(1R,2R,5S)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-2-carboxylic 3-chloro-6-[(1R,2R,5S)-2-isoprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.41 8.42 -50.15 0 4 -1 62 310.801 4 ↓

Analogs

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Popular Name: 3-chloro-6-[(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-2-carboxylic 3-chloro-6-[(1R,2S,5R)-2-isoprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.41 8.27 -51.08 0 4 -1 62 310.801 4 ↓

Analogs

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Popular Name: 3-chloro-6-[(1R,2S,5S)-2-isopropyl-5-methyl-cyclohexoxy]pyridine-2-carboxylic 3-chloro-6-[(1R,2S,5S)-2-isoprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.41 8.06 -50.7 0 4 -1 62 310.801 4 ↓

Analogs

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Popular Name: 2-tert-butoxy-6-(cyclohexoxy)pyridin-3-amine 2-tert-butoxy-6-(cyclohexoxy)pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.02 5.51 -4.05 2 4 0 57 264.369 4 ↓

Analogs

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Popular Name: 6-(cyclohexoxy)-2-isobutoxy-pyridin-3-amine 6-(cyclohexoxy)-2-isobutoxy-pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.96 4.22 -4.68 2 4 0 57 264.369 5 ↓

Analogs

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Popular Name: 6-(cyclohexoxy)-2-propoxy-pyridin-3-amine 6-(cyclohexoxy)-2-propoxy-pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.71 3.53 -4.85 2 4 0 57 250.342 5 ↓

Analogs

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Popular Name: 6-(cyclohexoxy)-2-isopropoxy-pyridin-3-amine 6-(cyclohexoxy)-2-isopropoxy-pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.57 3.71 -4.77 2 4 0 57 250.342 4 ↓

Analogs

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Popular Name: 6-(cyclohexoxy)-2-ethoxy-pyridin-3-amine 6-(cyclohexoxy)-2-ethoxy-pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 2.73 -4.99 2 4 0 57 236.315 4 ↓

Analogs

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Popular Name: 6-(cyclohexoxy)-2-methoxy-pyridin-3-amine 6-(cyclohexoxy)-2-methoxy-pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 1.79 -5.08 2 4 0 57 222.288 3 ↓

Analogs

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Popular Name: 2-tert-butoxy-6-(4-methylcyclohexoxy)pyridin-3-amine 2-tert-butoxy-6-(4-methylcyclohe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.79 6.2 -3.7 2 4 0 57 278.396 4 ↓
Lo Low (pH 4.5-6) 3.79 6.22 -22.89 3 4 1 59 279.404 4 ↓

Analogs

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Popular Name: 2-isobutoxy-6-(4-methylcyclohexoxy)pyridin-3-amine 2-isobutoxy-6-(4-methylcyclohexo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.73 4.9 -4.32 2 4 0 57 278.396 5 ↓

Analogs

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Popular Name: 6-(4-methylcyclohexoxy)-2-propoxy-pyridin-3-amine 6-(4-methylcyclohexoxy)-2-propox…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.48 4.21 -4.48 2 4 0 57 264.369 5 ↓

Analogs

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Popular Name: 2-isopropoxy-6-(4-methylcyclohexoxy)pyridin-3-amine 2-isopropoxy-6-(4-methylcyclohex…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.35 4.39 -4.43 2 4 0 57 264.369 4 ↓
Lo Low (pH 4.5-6) 3.35 5.31 -23.99 3 4 1 59 265.377 4 ↓

Analogs

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Popular Name: 2-ethoxy-6-(4-methylcyclohexoxy)pyridin-3-amine 2-ethoxy-6-(4-methylcyclohexoxy)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 3.41 -4.64 2 4 0 57 250.342 4 ↓

Analogs

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Popular Name: 2-methoxy-6-(4-methylcyclohexoxy)pyridin-3-amine 2-methoxy-6-(4-methylcyclohexoxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.61 2.47 -4.8 2 4 0 57 236.315 3 ↓

Analogs

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Popular Name: 2-tert-butoxy-6-[(1S,2R)-2-ethylcyclohexoxy]pyridin-3-amine 2-tert-butoxy-6-[(1S,2R)-2-ethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.76 6.91 -3.56 2 4 0 57 292.423 5 ↓
Lo Low (pH 4.5-6) 4.76 6.93 -22.61 3 4 1 59 293.431 5 ↓

Analogs

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Popular Name: 2-tert-butoxy-6-[(1S,2S)-2-ethylcyclohexoxy]pyridin-3-amine 2-tert-butoxy-6-[(1S,2S)-2-ethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.76 6.81 -3.8 2 4 0 57 292.423 5 ↓
Lo Low (pH 4.5-6) 4.76 6.84 -22.27 3 4 1 59 293.431 5 ↓

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