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ZINC Item

Suppliers, Protomers, & Similar Substances

11797971

Analogs

11953030

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[3-[(4-fluorophenyl)methoxy]-4-methoxy-phenyl]thiazol-4-yl]acetic 2-[2-[3-[(4-fluorophenyl)methoxy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.86	1.05	-55.2	0	5	-1	71	372.397	7	↓ MOL2 SDF SMILES Flexibase

11798084

Analogs

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Popular Name: 2-[3-[(3-chlorophenyl)methoxy]phenyl]-4-ethyl-thiazole-5-carboxylic 2-[3-[(3-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.67	-0.44	-52.78	0	4	-1	62	372.853	6	↓ MOL2 SDF SMILES Flexibase

11798122

Analogs

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Popular Name: 2-[2-[3-(p-tolylmethoxy)phenyl]thiazol-4-yl]acetic 2-[2-[3-(p-tolylmethoxy)phenyl]t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.53	0.31	-55.61	0	4	-1	62	338.408	6	↓ MOL2 SDF SMILES Flexibase

11799135

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2-fluorophenyl)methoxy]phenyl]-4-methyl-thiazole-5-carboxylic 2-[3-[(2-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.56	0.43	-50.36	0	4	-1	62	342.371	5	↓ MOL2 SDF SMILES Flexibase

11799396

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(4-fluorophenyl)methoxy]phenyl]-4-methyl-thiazole-5-carboxylic 2-[3-[(4-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.61	0.32	-52.46	0	4	-1	62	342.371	5	↓ MOL2 SDF SMILES Flexibase

11799645

Analogs

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Popular Name: 2-[2-[3-[(2-fluorophenyl)methoxy]phenyl]thiazol-4-yl]acetic 2-[2-[3-[(2-fluorophenyl)methoxy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.19	0.83	-55.15	0	4	-1	62	342.371	6	↓ MOL2 SDF SMILES Flexibase

11799906

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[3-[(4-fluorophenyl)methoxy]phenyl]thiazol-4-yl]acetic 2-[2-[3-[(4-fluorophenyl)methoxy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.24	0.72	-55.92	0	4	-1	62	342.371	6	↓ MOL2 SDF SMILES Flexibase

35895167

Analogs

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Popular Name: 2-[3-[(3-fluorophenyl)methoxy]phenyl]thiazole-4-carboxylic 2-[3-[(3-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.37	9.18	-56.34	0	4	-1	62	328.344	5	↓ MOL2 SDF SMILES Flexibase

11800292

Analogs

11824238
11958504

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2-chlorophenyl)methoxy]-4-methoxy-phenyl]thiazole-4-carboxylic 2-[3-[(2-chlorophenyl)methoxy]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.47	-0.23	-55.93	0	5	-1	71	374.825	6	↓ MOL2 SDF SMILES Flexibase

11800456

Analogs

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Popular Name: 2-[3-[(3,4-dichlorophenyl)methoxy]phenyl]thiazole-4-carboxylic 2-[3-[(3,4-dichlorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.51	-0.73	-57.39	0	4	-1	62	379.244	5	↓ MOL2 SDF SMILES Flexibase

11800720

Analogs

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Popular Name: 2-[3-[(2,6-dichlorophenyl)methoxy]phenyl]thiazole-4-carboxylic 2-[3-[(2,6-dichlorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.49	-0.76	-56.9	0	4	-1	62	379.244	5	↓ MOL2 SDF SMILES Flexibase

35895561

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-methoxyethyl)-2-[3-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-(2-methoxyethyl)-2-[3-[[4-(tri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.73	7.76	-11.6	1	5	0	60	436.455	9	↓ MOL2 SDF SMILES Flexibase

35895565

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-propyl-2-[3-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-propyl-2-[3-[[4-(trifluorometh…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.62	9.44	-10.45	1	4	0	51	420.456	8	↓ MOL2 SDF SMILES Flexibase

35895570

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-dimethylaminoethyl)-2-[3-[(2-fluorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-(2-dimethylaminoethyl)-2-[3-[(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.99	9.13	-41.46	2	5	1	56	400.499	8	↓ MOL2 SDF SMILES Flexibase

35895588

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-dimethylaminoethyl)-2-[3-(m-tolylmethoxy)phenyl]thiazole-4-carboxamide N-(2-dimethylaminoethyl)-2-[3-(m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.30	9.62	-42.03	2	5	1	56	396.536	8	↓ MOL2 SDF SMILES Flexibase

35895589

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-isopentyl-2-[3-(m-tolylmethoxy)phenyl]thiazole-4-carboxamide N-isopentyl-2-[3-(m-tolylmethoxy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.92	10.39	-8.99	1	4	0	51	394.54	8	↓ MOL2 SDF SMILES Flexibase

35895593

Analogs

34712846

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(3-chlorophenyl)methoxy]phenyl]-N-ethyl-N-methyl-thiazole-4-carboxamide 2-[3-[(3-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.12	10.92	-10.36	0	4	0	42	386.904	6	↓ MOL2 SDF SMILES Flexibase

35895595

Analogs

34712890

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(3-fluorophenyl)methoxy]phenyl]-N-(2-methoxyethyl)thiazole-4-carboxamide 2-[3-[(3-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.97	6.83	-11.56	1	5	0	60	386.448	8	↓ MOL2 SDF SMILES Flexibase

35895597

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(3-fluorophenyl)methoxy]phenyl]-N-isopropyl-thiazole-4-carboxamide 2-[3-[(3-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.66	8.56	-10.46	1	4	0	51	370.449	6	↓ MOL2 SDF SMILES Flexibase

35895601

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-dimethylaminoethyl)-2-[3-[(3-fluorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-(2-dimethylaminoethyl)-2-[3-[(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.02	9.03	-43.23	2	5	1	56	400.499	8	↓ MOL2 SDF SMILES Flexibase

35895603

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2-chlorophenyl)methoxy]phenyl]-N-(2-methoxyethyl)thiazole-4-carboxamide 2-[3-[(2-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.46	7.34	-9.67	1	5	0	60	402.903	8	↓ MOL2 SDF SMILES Flexibase

35895606

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2-chlorophenyl)methoxy]phenyl]-N-isopropyl-thiazole-4-carboxamide 2-[3-[(2-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.15	9.08	-8.65	1	4	0	51	386.904	6	↓ MOL2 SDF SMILES Flexibase

35895607

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2-chlorophenyl)methoxy]phenyl]-N-ethyl-thiazole-4-carboxamide 2-[3-[(2-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.85	8.25	-8.62	1	4	0	51	372.877	6	↓ MOL2 SDF SMILES Flexibase

35895610

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2-chlorophenyl)methoxy]phenyl]-N-(2-dimethylaminoethyl)thiazole-4-carboxamide 2-[3-[(2-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.51	9.53	-41.03	2	5	1	56	416.954	8	↓ MOL2 SDF SMILES Flexibase

35895613

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2-chlorophenyl)methoxy]phenyl]-N-isopentyl-thiazole-4-carboxamide 2-[3-[(2-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	6.13	10.3	-8.22	1	4	0	51	414.958	8	↓ MOL2 SDF SMILES Flexibase

35895615

Analogs

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Popular Name: 2-[3-[(2,6-difluorophenyl)methoxy]phenyl]-N-isobutyl-thiazole-4-carboxamide 2-[3-[(2,6-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.20	9.26	-10.36	1	4	0	51	402.466	7	↓ MOL2 SDF SMILES Flexibase

35895622

Analogs

35895625

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2,6-difluorophenyl)methoxy]phenyl]-N,N-diethyl-thiazole-4-carboxamide 2-[3-[(2,6-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.08	11.72	-11.1	0	4	0	42	402.466	7	↓ MOL2 SDF SMILES Flexibase

35895625

Analogs

35895622

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2,6-difluorophenyl)methoxy]phenyl]-N-ethyl-N-methyl-thiazole-4-carboxamide 2-[3-[(2,6-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.70	10.47	-11.28	0	4	0	42	388.439	6	↓ MOL2 SDF SMILES Flexibase

35895627

Analogs

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Popular Name: 2-[3-[(2,4-difluorophenyl)methoxy]phenyl]-N-isopropyl-thiazole-4-carboxamide 2-[3-[(2,4-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.78	8.73	-8.88	1	4	0	51	388.439	6	↓ MOL2 SDF SMILES Flexibase

35895628

Analogs

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Popular Name: 2-[3-[(2,4-difluorophenyl)methoxy]phenyl]-N-propyl-thiazole-4-carboxamide 2-[3-[(2,4-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.98	8.67	-8.64	1	4	0	51	388.439	7	↓ MOL2 SDF SMILES Flexibase

35895629

Analogs

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Popular Name: 2-[3-[(2,4-difluorophenyl)methoxy]phenyl]-N-(2-dimethylaminoethyl)thiazole-4-carboxamide 2-[3-[(2,4-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.13	9.2	-41.59	2	5	1	56	418.489	8	↓ MOL2 SDF SMILES Flexibase

35895636

Analogs

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Popular Name: 2-[3-[(3,4-difluorophenyl)methoxy]phenyl]-N-isopentyl-thiazole-4-carboxamide 2-[3-[(3,4-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.76	9.84	-11.94	1	4	0	51	416.493	8	↓ MOL2 SDF SMILES Flexibase

35895638

Analogs

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Popular Name: 2-[3-[(3,4-difluorophenyl)methoxy]phenyl]-N,N-diethyl-thiazole-4-carboxamide 2-[3-[(3,4-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.10	11.74	-12.74	0	4	0	42	402.466	7	↓ MOL2 SDF SMILES Flexibase

35895646

Analogs

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Popular Name: N-(2-dimethylaminoethyl)-2-[3-[(3-methoxyphenyl)methoxy]phenyl]thiazole-4-carboxamide N-(2-dimethylaminoethyl)-2-[3-[(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.91	8.26	-43.49	2	6	1	65	412.535	9	↓ MOL2 SDF SMILES Flexibase

35895649

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-isopentyl-2-[3-[(3-methoxyphenyl)methoxy]phenyl]thiazole-4-carboxamide N-isopentyl-2-[3-[(3-methoxyphen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.53	9.02	-10.59	1	5	0	60	410.539	9	↓ MOL2 SDF SMILES Flexibase

35895652

Analogs

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Popular Name: N-ethyl-2-[3-[(3-methoxyphenyl)methoxy]phenyl]-N-methyl-thiazole-4-carboxamide N-ethyl-2-[3-[(3-methoxyphenyl)m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.50	9.7	-11.54	0	5	0	52	382.485	7	↓ MOL2 SDF SMILES Flexibase

35895661

Analogs

35897192

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Popular Name: 2-[3-[(2-chloro-6-fluoro-phenyl)methoxy]phenyl]-N-isobutyl-thiazole-4-carboxamide 2-[3-[(2-chloro-6-fluoro-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.72	9.67	-9.79	1	4	0	51	418.921	7	↓ MOL2 SDF SMILES Flexibase

35895663

Analogs

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Popular Name: 2-[3-[(2-chloro-6-fluoro-phenyl)methoxy]phenyl]-N-isopropyl-thiazole-4-carboxamide 2-[3-[(2-chloro-6-fluoro-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.27	8.96	-10.12	1	4	0	51	404.894	6	↓ MOL2 SDF SMILES Flexibase

35895665

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2-chloro-6-fluoro-phenyl)methoxy]phenyl]-N-ethyl-thiazole-4-carboxamide 2-[3-[(2-chloro-6-fluoro-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.97	8.14	-10.14	1	4	0	51	390.867	6	↓ MOL2 SDF SMILES Flexibase

35895669

Analogs

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Popular Name: 2-[3-[(2-chloro-6-fluoro-phenyl)methoxy]phenyl]-N-propyl-thiazole-4-carboxamide 2-[3-[(2-chloro-6-fluoro-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.47	8.9	-9.97	1	4	0	51	404.894	7	↓ MOL2 SDF SMILES Flexibase

35895674

Analogs

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Popular Name: N-allyl-2-[3-[(2-chloro-6-fluoro-phenyl)methoxy]phenyl]thiazole-4-carboxamide N-allyl-2-[3-[(2-chloro-6-fluoro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.24	8.7	-9.92	1	4	0	51	402.878	7	↓ MOL2 SDF SMILES Flexibase

35895682

Analogs

35897197

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Popular Name: 2-[3-[(2,5-difluorophenyl)methoxy]phenyl]-N-isobutyl-thiazole-4-carboxamide 2-[3-[(2,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.22	9.43	-8.89	1	4	0	51	402.466	7	↓ MOL2 SDF SMILES Flexibase

35895683

Analogs

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Popular Name: 2-[3-[(2,5-difluorophenyl)methoxy]phenyl]-N-(2-methoxyethyl)thiazole-4-carboxamide 2-[3-[(2,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.09	6.99	-10.23	1	5	0	60	404.438	8	↓ MOL2 SDF SMILES Flexibase

35895689

Analogs

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Popular Name: 2-[3-[(2,5-difluorophenyl)methoxy]phenyl]-N-ethyl-thiazole-4-carboxamide 2-[3-[(2,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.48	7.91	-9.27	1	4	0	51	374.412	6	↓ MOL2 SDF SMILES Flexibase

35895694

Analogs

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Popular Name: 2-[3-[(2,5-difluorophenyl)methoxy]phenyl]-N-(2-dimethylaminoethyl)thiazole-4-carboxamide 2-[3-[(2,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.13	9.2	-41.76	2	5	1	56	418.489	8	↓ MOL2 SDF SMILES Flexibase

35895697

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-allyl-2-[3-[(2,5-difluorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-allyl-2-[3-[(2,5-difluoropheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.75	8.47	-9.04	1	4	0	51	386.423	7	↓ MOL2 SDF SMILES Flexibase

35895699

Analogs

35897199

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(2,5-difluorophenyl)methoxy]phenyl]-N,N-diethyl-thiazole-4-carboxamide 2-[3-[(2,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.10	11.9	-9.72	0	4	0	42	402.466	7	↓ MOL2 SDF SMILES Flexibase

35895703

Analogs

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Popular Name: 2-[3-[(3,4-dichlorophenyl)methoxy]phenyl]-N-isobutyl-thiazole-4-carboxamide 2-[3-[(3,4-dichlorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	6.25	10.16	-10.25	1	4	0	51	435.376	7	↓ MOL2 SDF SMILES Flexibase

35895704

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(3,4-dichlorophenyl)methoxy]phenyl]-N-(2-methoxyethyl)thiazole-4-carboxamide 2-[3-[(3,4-dichlorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.12	7.73	-11.68	1	5	0	60	437.348	8	↓ MOL2 SDF SMILES Flexibase

35895706

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-[(3,4-dichlorophenyl)methoxy]phenyl]-N-ethyl-thiazole-4-carboxamide 2-[3-[(3,4-dichlorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.51	8.64	-10.61	1	4	0	51	407.322	6	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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