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ZINC Item

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11798279

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[5-chloro-2-[(4-fluorophenyl)methoxy]phenyl]-4-methyl-thiazole-5-carboxylic 2-[5-chloro-2-[(4-fluorophenyl)m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.24	0.5	-55.66	0	4	-1	62	376.816	5	↓ MOL2 SDF SMILES Flexibase

11798798

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2-chloro-6-fluoro-phenyl)methoxy]phenyl]-4-methyl-thiazole-5-carboxylic 2-[2-[(2-chloro-6-fluoro-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.17	0.46	-56.02	0	4	-1	62	376.816	5	↓ MOL2 SDF SMILES Flexibase

11800189

Analogs

34613519

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[5-chloro-2-[(4-chlorophenyl)methoxy]phenyl]thiazole-4-carboxylic 2-[5-chloro-2-[(4-chlorophenyl)m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.53	-0.46	-60.91	0	4	-1	62	379.244	5	↓ MOL2 SDF SMILES Flexibase

11801011

Analogs

11994890
34613519

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Popular Name: 2-(2-benzyloxy-5-chloro-phenyl)thiazole-4-carboxylic 2-(2-benzyloxy-5-chloro-phenyl)t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.86	-0.31	-60.21	0	4	-1	62	344.799	5	↓ MOL2 SDF SMILES Flexibase

35895842

Analogs

34713678

Draw Identity 99% 90% 80% 70%

Popular Name: N-isobutyl-2-[2-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-isobutyl-2-[2-[[4-(trifluorome…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.84	10.38	-11.41	1	4	0	51	434.483	8	↓ MOL2 SDF SMILES Flexibase

35895844

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-dimethylaminoethyl)-2-[2-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-(2-dimethylaminoethyl)-2-[2-[[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.75	10.15	-43.26	2	5	1	56	450.506	9	↓ MOL2 SDF SMILES Flexibase

35895847

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2-fluorophenyl)methoxy]phenyl]-N-isobutyl-thiazole-4-carboxamide 2-[2-[(2-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.06	9.31	-9.44	1	4	0	51	384.476	7	↓ MOL2 SDF SMILES Flexibase

35895848

Analogs

34714143

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2-fluorophenyl)methoxy]phenyl]-N-(2-methoxyethyl)thiazole-4-carboxamide 2-[2-[(2-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.92	6.88	-10.86	1	5	0	60	386.448	8	↓ MOL2 SDF SMILES Flexibase

35895852

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2-fluorophenyl)methoxy]phenyl]-N-isopropyl-thiazole-4-carboxamide 2-[2-[(2-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.61	8.62	-9.85	1	4	0	51	370.449	6	↓ MOL2 SDF SMILES Flexibase

35895854

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-ethyl-2-[2-[(2-fluorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-ethyl-2-[2-[(2-fluorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.32	7.79	-9.85	1	4	0	51	356.422	6	↓ MOL2 SDF SMILES Flexibase

35895857

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2-fluorophenyl)methoxy]phenyl]-N-propyl-thiazole-4-carboxamide 2-[2-[(2-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.82	8.56	-9.63	1	4	0	51	370.449	7	↓ MOL2 SDF SMILES Flexibase

35895890

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2-benzyloxyphenyl)-N-propyl-thiazole-4-carboxamide 2-(2-benzyloxyphenyl)-N-propyl-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.70	8.62	-9.9	1	4	0	51	352.459	7	↓ MOL2 SDF SMILES Flexibase

35895891

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2-benzyloxyphenyl)-N-(2-dimethylaminoethyl)thiazole-4-carboxamide 2-(2-benzyloxyphenyl)-N-(2-dimet…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.85	9.15	-41.45	2	5	1	56	382.509	8	↓ MOL2 SDF SMILES Flexibase

35895895

Analogs

34714056

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2-benzyloxyphenyl)-N-ethyl-N-methyl-thiazole-4-carboxamide 2-(2-benzyloxyphenyl)-N-ethyl-N-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.44	10.58	-10.7	0	4	0	42	352.459	6	↓ MOL2 SDF SMILES Flexibase

35895911

Analogs

35895915

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(3-chlorophenyl)methoxy]phenyl]-N-isobutyl-thiazole-4-carboxamide 2-[2-[(3-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.60	9.89	-10.39	1	4	0	51	400.931	7	↓ MOL2 SDF SMILES Flexibase

35895915

Analogs

35895911

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(3-chlorophenyl)methoxy]phenyl]-N-propyl-thiazole-4-carboxamide 2-[2-[(3-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.36	9.13	-10.6	1	4	0	51	386.904	7	↓ MOL2 SDF SMILES Flexibase

35895919

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(3-chlorophenyl)methoxy]phenyl]-N,N-diethyl-thiazole-4-carboxamide 2-[2-[(3-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.47	12.36	-11.14	0	4	0	42	400.931	7	↓ MOL2 SDF SMILES Flexibase

35895926

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2,6-difluorophenyl)methoxy]phenyl]-N-(2-dimethylaminoethyl)thiazole-4-carboxamide 2-[2-[(2,6-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.08	9.21	-42.62	2	5	1	56	418.489	8	↓ MOL2 SDF SMILES Flexibase

35895930

Analogs

34714143

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2,4-difluorophenyl)methoxy]phenyl]-N-(2-methoxyethyl)thiazole-4-carboxamide 2-[2-[(2,4-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.06	6.95	-10.58	1	5	0	60	404.438	8	↓ MOL2 SDF SMILES Flexibase

35895937

Analogs

35895940

Draw Identity 99% 90% 80% 70%

Popular Name: N-isobutyl-2-[2-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-isobutyl-2-[2-[[3-(trifluorome…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.82	10.4	-11.42	1	4	0	51	434.483	8	↓ MOL2 SDF SMILES Flexibase

35895938

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-methoxyethyl)-2-[2-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-(2-methoxyethyl)-2-[2-[[3-(tri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.68	7.96	-12.92	1	5	0	60	436.455	9	↓ MOL2 SDF SMILES Flexibase

35895940

Analogs

35895937

Draw Identity 99% 90% 80% 70%

Popular Name: N-propyl-2-[2-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-propyl-2-[2-[[3-(trifluorometh…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.57	9.64	-11.64	1	4	0	51	420.456	8	↓ MOL2 SDF SMILES Flexibase

35895941

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-dimethylaminoethyl)-2-[2-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-(2-dimethylaminoethyl)-2-[2-[[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.72	10.17	-43.13	2	5	1	56	450.506	9	↓ MOL2 SDF SMILES Flexibase

35895945

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(4-chlorophenyl)methoxy]phenyl]-N-propyl-thiazole-4-carboxamide 2-[2-[(4-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.38	9.14	-10.59	1	4	0	51	386.904	7	↓ MOL2 SDF SMILES Flexibase

35895947

Analogs

35895948

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(4-chlorophenyl)methoxy]phenyl]-N,N-diethyl-thiazole-4-carboxamide 2-[2-[(4-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.50	12.32	-11.09	0	4	0	42	400.931	7	↓ MOL2 SDF SMILES Flexibase

35895948

Analogs

35895947

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(4-chlorophenyl)methoxy]phenyl]-N-ethyl-N-methyl-thiazole-4-carboxamide 2-[2-[(4-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.12	11.1	-11.37	0	4	0	42	386.904	6	↓ MOL2 SDF SMILES Flexibase

35895950

Analogs

35895951

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Popular Name: 2-[2-[(2,4-dichlorophenyl)methoxy]phenyl]-N,N-diethyl-thiazole-4-carboxamide 2-[2-[(2,4-dichlorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	6.10	12.71	-9.52	0	4	0	42	435.376	7	↓ MOL2 SDF SMILES Flexibase

35895951

Analogs

35895950

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2,4-dichlorophenyl)methoxy]phenyl]-N-ethyl-N-methyl-thiazole-4-carboxamide 2-[2-[(2,4-dichlorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.73	11.44	-9.72	0	4	0	42	421.349	6	↓ MOL2 SDF SMILES Flexibase

35895955

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(3,5-difluorophenyl)methoxy]phenyl]-N-(2-dimethylaminoethyl)thiazole-4-carboxamide 2-[2-[(3,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.11	9.29	-42.93	2	5	1	56	418.489	8	↓ MOL2 SDF SMILES Flexibase

35895957

Analogs

34723250

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2,5-difluorophenyl)methoxy]phenyl]-N-isobutyl-thiazole-4-carboxamide 2-[2-[(2,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.20	9.38	-10.21	1	4	0	51	402.466	7	↓ MOL2 SDF SMILES Flexibase

35895959

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2,5-difluorophenyl)methoxy]phenyl]-N-isopropyl-thiazole-4-carboxamide 2-[2-[(2,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.75	8.69	-10.68	1	4	0	51	388.439	6	↓ MOL2 SDF SMILES Flexibase

35895964

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[(2,5-difluorophenyl)methoxy]phenyl]-N-(2-dimethylaminoethyl)thiazole-4-carboxamide 2-[2-[(2,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.11	9.15	-41.87	2	5	1	56	418.489	8	↓ MOL2 SDF SMILES Flexibase

11802690

Analogs

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Popular Name: 4-ethyl-2-[2-[(4-nitrophenyl)methoxy]phenyl]thiazole-5-carboxylic 4-ethyl-2-[2-[(4-nitrophenyl)met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.96	0.55	-62.04	0	7	-1	108	383.405	7	↓ MOL2 SDF SMILES Flexibase

35897248

Analogs

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Popular Name: 2-(2-benzyloxyphenyl)-N-isopropyl-N-methyl-thiazole-4-carboxamide 2-(2-benzyloxyphenyl)-N-isopropy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.74	11.08	-10.7	0	4	0	42	366.486	6	↓ MOL2 SDF SMILES Flexibase

35897257

Analogs

34723204

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Popular Name: 2-[2-[(2,6-difluorophenyl)methoxy]phenyl]-N-isopropyl-N-methyl-thiazole-4-carboxamide 2-[2-[(2,6-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.97	11.13	-11.75	0	4	0	42	402.466	6	↓ MOL2 SDF SMILES Flexibase

11804498

Analogs

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Popular Name: 2-(2-benzyloxy-4-methoxy-phenyl)-4-methyl-thiazole-5-carboxylic 2-(2-benzyloxy-4-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.46	-0.05	-55.42	0	5	-1	71	354.407	6	↓ MOL2 SDF SMILES Flexibase

11822786

Analogs

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Popular Name: 4-ethyl-2-[3-methoxy-2-(o-tolylmethoxy)phenyl]thiazole-5-carboxylic 4-ethyl-2-[3-methoxy-2-(o-tolylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.21	0.75	-57.02	0	5	-1	71	382.461	7	↓ MOL2 SDF SMILES Flexibase

11822890

Analogs

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Popular Name: 4-ethyl-2-[2-[(2-fluorophenyl)methoxy]phenyl]thiazole-5-carboxylic 4-ethyl-2-[2-[(2-fluorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.11	1	-55.19	0	4	-1	62	356.398	6	↓ MOL2 SDF SMILES Flexibase

11823100

Analogs

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Popular Name: 4-ethyl-2-[2-[(2-fluorophenyl)methoxy]-4-methoxy-phenyl]thiazole-5-carboxylic 4-ethyl-2-[2-[(2-fluorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.14	1.03	-54.3	0	5	-1	71	386.424	7	↓ MOL2 SDF SMILES Flexibase

11823198

Analogs

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Popular Name: 2-[4-methoxy-2-(o-tolylmethoxy)phenyl]thiazole-4-carboxylic 2-[4-methoxy-2-(o-tolylmethoxy)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.64	0.37	-59.93	0	5	-1	71	354.407	6	↓ MOL2 SDF SMILES Flexibase

11823345

Analogs

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Popular Name: 4-ethyl-2-[2-[(4-fluorophenyl)methoxy]phenyl]thiazole-5-carboxylic 4-ethyl-2-[2-[(4-fluorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.16	0.77	-58.12	0	4	-1	62	356.398	6	↓ MOL2 SDF SMILES Flexibase

11823688

Analogs

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Popular Name: 2-[4-methoxy-2-(m-tolylmethoxy)phenyl]thiazole-4-carboxylic 2-[4-methoxy-2-(m-tolylmethoxy)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.66	0.19	-58.62	0	5	-1	71	354.407	6	↓ MOL2 SDF SMILES Flexibase

11823873

Analogs

11960780
11994287
11994545

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Popular Name: 2-[3-methoxy-2-[(4-nitrophenyl)methoxy]phenyl]thiazole-4-carboxylic 2-[3-methoxy-2-[(4-nitrophenyl)m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.97	0.89	-60.89	0	8	-1	117	385.377	7	↓ MOL2 SDF SMILES Flexibase

11824000

Analogs

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Popular Name: 2-[2-[(2-fluorophenyl)methoxy]-4-methoxy-phenyl]thiazole-4-carboxylic 2-[2-[(2-fluorophenyl)methoxy]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.35	0.84	-58.09	0	5	-1	71	358.37	6	↓ MOL2 SDF SMILES Flexibase

11824168

Analogs

11863741

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Popular Name: 2-[4-methoxy-2-(p-tolylmethoxy)phenyl]thiazole-4-carboxylic 2-[4-methoxy-2-(p-tolylmethoxy)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.68	0.19	-58.67	0	5	-1	71	354.407	6	↓ MOL2 SDF SMILES Flexibase

11824310

Analogs

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Popular Name: 2-[5-chloro-2-(o-tolylmethoxy)phenyl]-4-ethyl-thiazole-5-carboxylic 2-[5-chloro-2-(o-tolylmethoxy)ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	6.05	0.38	-58.37	0	4	-1	62	386.88	6	↓ MOL2 SDF SMILES Flexibase

11824536

Analogs

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Popular Name: 2-[2-[(3-chlorophenyl)methoxy]phenyl]-4-methyl-thiazole-5-carboxylic 2-[2-[(3-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.08	-0.23	-56.83	0	4	-1	62	358.826	5	↓ MOL2 SDF SMILES Flexibase

11824989

Analogs

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Popular Name: 2-[5-chloro-2-(m-tolylmethoxy)phenyl]thiazole-4-carboxylic 2-[5-chloro-2-(m-tolylmethoxy)ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.28	0.01	-60.16	0	4	-1	62	358.826	5	↓ MOL2 SDF SMILES Flexibase

11825726

Analogs

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Popular Name: 2-[2-[2-[(3-chlorophenyl)methoxy]-3-methoxy-phenyl]thiazol-4-yl]acetic 2-[2-[2-[(3-chlorophenyl)methoxy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.52	0.69	-57.77	0	5	-1	71	388.852	7	↓ MOL2 SDF SMILES Flexibase

11825995

Analogs

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Popular Name: 2-[2-[(2-chlorophenyl)methoxy]-3-methoxy-phenyl]-4-methyl-thiazole-5-carboxylic 2-[2-[(2-chlorophenyl)methoxy]-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.87	0.21	-55.02	0	5	-1	71	388.852	6	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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