UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

41200924
41200924
41200957
41200957
41200960
41200960
41201126
41201126
41201129
41201129

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl(phenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.27 8.71 -31.29 2 2 1 29 271.409 4 ↓
Hi High (pH 8-9.5) 3.27 7.44 -6.14 1 2 0 25 270.401 4 ↓

Analogs

41200957
41200957
41200960
41200960
41201126
41201126
41201129
41201129
41200921
41200921

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl(phenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.27 8.79 -32.53 2 2 1 29 271.409 4 ↓
Hi High (pH 8-9.5) 3.27 7.6 -4.58 1 2 0 25 270.401 4 ↓

Analogs

41200942
41200942

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(3-fluorophenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 8.77 -34.79 2 2 1 29 289.399 4 ↓
Mid Mid (pH 6-8) 3.41 7.51 -5.68 1 2 0 25 288.391 4 ↓

Analogs

41200939
41200939

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Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(3-fluorophenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 8.86 -36.08 2 2 1 29 289.399 4 ↓
Mid Mid (pH 6-8) 3.41 7.67 -5.89 1 2 0 25 288.391 4 ↓

Analogs

41200948
41200948
43395054
43395054
43395055
43395055

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl(m-tolyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 9.37 -31.24 2 2 1 29 285.436 4 ↓
Hi High (pH 8-9.5) 3.70 8.12 -6.21 1 2 0 25 284.428 4 ↓

Analogs

43395054
43395054
43395055
43395055
41200945
41200945

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl(m-tolyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 9.46 -32.5 2 2 1 29 285.436 4 ↓
Hi High (pH 8-9.5) 3.70 8.28 -4.65 1 2 0 25 284.428 4 ↓

Analogs

41200960
41200960
41201126
41201126
41201129
41201129
41200921
41200921
41200924
41200924

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(4-ethylphenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.18 10.15 -31.34 2 2 1 29 299.463 5 ↓
Hi High (pH 8-9.5) 4.18 8.89 -5.98 1 2 0 25 298.455 5 ↓

Analogs

41201126
41201126
41201129
41201129
41200921
41200921
41200924
41200924
41200957
41200957

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(4-ethylphenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.18 10.24 -32.63 2 2 1 29 299.463 5 ↓
Hi High (pH 8-9.5) 4.18 9.05 -4.44 1 2 0 25 298.455 5 ↓

Analogs

41200985
41200985

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Popular Name: N-[(S)-(3,4-difluorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(S)-(3,4-difluorophenyl)-(5,6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.53 8.81 -41.1 2 2 1 29 307.389 4 ↓
Mid Mid (pH 6-8) 3.53 7.83 -9.09 1 2 0 25 306.381 4 ↓

Analogs

41200982
41200982

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Popular Name: N-[(R)-(3,4-difluorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(R)-(3,4-difluorophenyl)-(5,6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.53 8.92 -41.46 2 2 1 29 307.389 4 ↓
Mid Mid (pH 6-8) 3.53 7.72 -5.22 1 2 0 25 306.381 4 ↓

Analogs

41201006
41201006
41201114
41201114
41201117
41201117

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(2,4-dimethylphenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.10 9.54 -31.58 2 2 1 29 299.463 4 ↓
Hi High (pH 8-9.5) 4.10 9.07 -5.75 1 2 0 25 298.455 4 ↓

Analogs

41201114
41201114
41201117
41201117
41201003
41201003

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(2,4-dimethylphenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.10 10.01 -32.74 2 2 1 29 299.463 4 ↓
Hi High (pH 8-9.5) 4.10 9.17 -4.87 1 2 0 25 298.455 4 ↓

Analogs

41201039
41201039

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Popular Name: N-[(S)-(3-bromo-4-fluoro-phenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(S)-(3-bromo-4-fluoro-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.17 9.36 -39.5 2 2 1 29 368.295 4 ↓
Mid Mid (pH 6-8) 4.17 8.36 -7.66 1 2 0 25 367.287 4 ↓

Analogs

41201036
41201036

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Popular Name: N-[(R)-(3-bromo-4-fluoro-phenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(R)-(3-bromo-4-fluoro-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.17 9.45 -39.82 2 2 1 29 368.295 4 ↓
Mid Mid (pH 6-8) 4.17 8.27 -4.53 1 2 0 25 367.287 4 ↓

Analogs

41201077
41201077

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Popular Name: N-[(S)-(2,4-difluorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(S)-(2,4-difluorophenyl)-(5,6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.53 8.61 -35.04 2 2 1 29 307.389 4 ↓
Mid Mid (pH 6-8) 3.53 8.1 -4.63 1 2 0 25 306.381 4 ↓

Analogs

41201074
41201074

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Popular Name: N-[(R)-(2,4-difluorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(R)-(2,4-difluorophenyl)-(5,6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.53 9 -36.78 2 2 1 29 307.389 4 ↓
Mid Mid (pH 6-8) 3.53 7.68 -3.7 1 2 0 25 306.381 4 ↓

Analogs

41201090
41201090

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Popular Name: N-[(S)-(4-chlorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(S)-(4-chlorophenyl)-(5,6-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.95 9.23 -34.89 2 2 1 29 305.854 4 ↓
Mid Mid (pH 6-8) 3.95 7.96 -5.86 1 2 0 25 304.846 4 ↓

Analogs

41201087
41201087

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Popular Name: N-[(R)-(4-chlorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(R)-(4-chlorophenyl)-(5,6-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.95 9.31 -36.36 2 2 1 29 305.854 4 ↓
Mid Mid (pH 6-8) 3.95 8.12 -4.21 1 2 0 25 304.846 4 ↓

Analogs

41201099
41201099

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(2-methoxyphenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 7.87 -30.24 2 3 1 39 301.435 5 ↓
Hi High (pH 8-9.5) 3.28 7.36 -6.55 1 3 0 34 300.427 5 ↓

Analogs

41201096
41201096

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Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(2-methoxyphenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 8.24 -31.44 2 3 1 39 301.435 5 ↓
Hi High (pH 8-9.5) 3.28 6.92 -5.67 1 3 0 34 300.427 5 ↓

Analogs

41201105
41201105

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Popular Name: N-[(S)-(3-chlorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(S)-(3-chlorophenyl)-(5,6-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.93 9.23 -33.93 2 2 1 29 305.854 4 ↓
Mid Mid (pH 6-8) 3.93 7.97 -5.25 1 2 0 25 304.846 4 ↓

Analogs

41201102
41201102

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Popular Name: N-[(R)-(3-chlorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(R)-(3-chlorophenyl)-(5,6-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.93 9.3 -35.16 2 2 1 29 305.854 4 ↓
Mid Mid (pH 6-8) 3.93 8.12 -5.02 1 2 0 25 304.846 4 ↓

Analogs

41201117
41201117
41201003
41201003
41201006
41201006

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl(o-tolyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.67 8.88 -31.53 2 2 1 29 285.436 4 ↓
Hi High (pH 8-9.5) 3.67 8.4 -5.67 1 2 0 25 284.428 4 ↓

Analogs

41201003
41201003
41201006
41201006
41201114
41201114

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl(o-tolyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.67 9.35 -32.69 2 2 1 29 285.436 4 ↓
Hi High (pH 8-9.5) 3.67 8.5 -4.74 1 2 0 25 284.428 4 ↓

Analogs

41201129
41201129
41200921
41200921
41200924
41200924
41200957
41200957
41200960
41200960

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl(p-tolyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 9.37 -32.13 2 2 1 29 285.436 4 ↓
Hi High (pH 8-9.5) 3.72 8.38 -6.12 1 2 0 25 284.428 4 ↓

Analogs

41200921
41200921
41200924
41200924
41200957
41200957
41200960
41200960
41201126
41201126

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl(p-tolyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 9.44 -31.9 2 2 1 29 285.436 4 ↓
Hi High (pH 8-9.5) 3.72 8.35 -6.56 1 2 0 25 284.428 4 ↓

Analogs

41201135
41201135

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Popular Name: N-[(S)-(4-bromophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(S)-(4-bromophenyl)-(5,6-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.08 9.33 -35.04 2 2 1 29 350.305 4 ↓
Mid Mid (pH 6-8) 4.08 8.07 -5.83 1 2 0 25 349.297 4 ↓

Analogs

41201132
41201132

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Popular Name: N-[(R)-(4-bromophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(R)-(4-bromophenyl)-(5,6-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.08 9.42 -36.48 2 2 1 29 350.305 4 ↓
Mid Mid (pH 6-8) 4.08 8.23 -4.13 1 2 0 25 349.297 4 ↓

Analogs

41201141
41201141

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(4-fluorophenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.44 8.77 -35.82 2 2 1 29 289.399 4 ↓
Hi High (pH 8-9.5) 3.44 7.51 -6.37 1 2 0 25 288.391 4 ↓

Analogs

41201138
41201138

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Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(4-fluorophenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.44 8.86 -37.24 2 2 1 29 289.399 4 ↓
Hi High (pH 8-9.5) 3.44 7.67 -4.68 1 2 0 25 288.391 4 ↓

Analogs

41201146
41201146

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Popular Name: N-[(S)-(3-bromophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(S)-(3-bromophenyl)-(5,6-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.06 9.33 -33.92 2 2 1 29 350.305 4 ↓
Mid Mid (pH 6-8) 4.06 8.07 -5.13 1 2 0 25 349.297 4 ↓

Analogs

41201143
41201143

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Popular Name: N-[(R)-(3-bromophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(R)-(3-bromophenyl)-(5,6-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.06 9.41 -35.17 2 2 1 29 350.305 4 ↓
Mid Mid (pH 6-8) 4.06 8.23 -4.92 1 2 0 25 349.297 4 ↓

Analogs

41201155
41201155

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(3-methoxyphenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.30 7.99 -32.33 2 3 1 39 301.435 5 ↓
Mid Mid (pH 6-8) 3.30 6.74 -8.62 1 3 0 34 300.427 5 ↓

Analogs

41201152
41201152

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Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(3-methoxyphenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.30 8.08 -33.62 2 3 1 39 301.435 5 ↓
Mid Mid (pH 6-8) 3.30 6.9 -5.87 1 3 0 34 300.427 5 ↓

Analogs

41201161
41201161

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Popular Name: N-[(S)-(2-chlorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(S)-(2-chlorophenyl)-(5,6-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.90 8.93 -30.87 2 2 1 29 305.854 4 ↓
Mid Mid (pH 6-8) 3.90 8.42 -5.33 1 2 0 25 304.846 4 ↓

Analogs

41201158
41201158

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Popular Name: N-[(R)-(2-chlorophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(R)-(2-chlorophenyl)-(5,6-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.90 9.23 -32.13 2 2 1 29 305.854 4 ↓
Mid Mid (pH 6-8) 3.90 8.03 -4.29 1 2 0 25 304.846 4 ↓

Analogs

41201189
41201189

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(4-methoxyphenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 7.99 -34.85 2 3 1 39 301.435 5 ↓
Hi High (pH 8-9.5) 3.33 7.01 -7.52 1 3 0 34 300.427 5 ↓

Analogs

41201187
41201187

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Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(4-methoxyphenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 8.06 -34.58 2 3 1 39 301.435 5 ↓
Hi High (pH 8-9.5) 3.33 6.95 -7.85 1 3 0 34 300.427 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(S)-(2-bromophenyl)-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)methyl]cyclopropanamine N-[(S)-(2-bromophenyl)-(5,6-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.03 8.96 -30.61 2 2 1 29 350.305 4 ↓
Mid Mid (pH 6-8) 4.03 8.46 -5.29 1 2 0 25 349.297 4 ↓

Analogs

41201232
41201232

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(4-methylsulfanylphenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 9.7 -35.14 2 2 1 29 317.503 5 ↓
Hi High (pH 8-9.5) 3.70 8.72 -7.16 1 2 0 25 316.495 5 ↓

Analogs

41201229
41201229

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Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(4-methylsulfanylphenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 9.78 -34.78 2 2 1 29 317.503 5 ↓
Hi High (pH 8-9.5) 3.70 8.68 -6.79 1 2 0 25 316.495 5 ↓

Analogs

41201238
41201238

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(2-fluorophenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.39 8.54 -31.74 2 2 1 29 289.399 4 ↓
Mid Mid (pH 6-8) 3.39 8.04 -5.79 1 2 0 25 288.391 4 ↓

Analogs

41201235
41201235

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Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(2-fluorophenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.39 8.93 -33.07 2 2 1 29 289.399 4 ↓
Mid Mid (pH 6-8) 3.39 7.62 -4.88 1 2 0 25 288.391 4 ↓

Analogs

41201259
41201259

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Popular Name: N-[(S)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(3,4-dimethylphenyl)methyl]cyclopropanamine N-[(S)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.10 9.91 -32.01 2 2 1 29 299.463 4 ↓
Hi High (pH 8-9.5) 4.10 8.93 -6.24 1 2 0 25 298.455 4 ↓

Analogs

41201256
41201256

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(R)-5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl-(3,4-dimethylphenyl)methyl]cyclopropanamine N-[(R)-5,6-dihydro-4H-cyclopenta…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.10 9.99 -31.65 2 2 1 29 299.463 4 ↓
Hi High (pH 8-9.5) 4.10 8.89 -6.62 1 2 0 25 298.455 4 ↓

Parameters Provided:

ring.id = 521753
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

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