UCSF
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Popular Name: 4-[amino(carbamoyl)BLAHyl]benzoic 4-[amino(carbamoyl)BLAHyl]benzoic

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Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
EF2K-1-E Serine/threonine-protein Kinase EEF2K (cluster #1 Of 2), Eukaryotic Eukaryotes 860 0.30 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
EF2K_HUMAN O00418 Serine/threonine-protein Kinase EEF2K, Human 860 0.30 Binding ≤ 1μM
EF2K_HUMAN O00418 Serine/threonine-protein Kinase EEF2K, Human 860 0.30 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.51 6.83 -65.98 5 6 0 123 395.484 3 ↓
Mid Mid (pH 6-8) 4.51 6.48 -49.88 4 6 -1 122 394.476 3 ↓

Parameters Provided:

ring.id = 543657
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 543657 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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