UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2-oxo-3-phenyl-imidazolidin-1-yl)-N-thiazol-2-yl-acetamide 2-(2-oxo-3-phenyl-imidazolidin-1…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.02 6.73 -24.63 1 6 0 66 302.359 4 ↓
Hi High (pH 8-9.5) 1.84 5.38 -53.79 0 6 -1 72 301.351 4 ↓

Analogs

6359186
6359186

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-methylthiazol-2-yl)-2-(2-oxo-3-phenyl-imidazolidin-1-yl)acetamide N-(4-methylthiazol-2-yl)-2-(2-ox…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 7 -19.78 1 6 0 66 316.386 4 ↓

Analogs

4503989
4503989

Draw Identity 99% 90% 80% 70%

Popular Name: N-(5-methylthiazol-2-yl)-2-(2-oxo-3-phenyl-imidazolidin-1-yl)acetamide N-(5-methylthiazol-2-yl)-2-(2-ox…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 7.55 -24.85 1 6 0 66 316.386 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(2-amino-2-oxo-ethyl)thiazol-2-yl]-2-(2-oxo-3-phenyl-imidazolidin-1-yl)acetamide N-[4-(2-amino-2-oxo-ethyl)thiazo…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.17 4 -28.08 3 8 0 109 359.411 6 ↓
Hi High (pH 8-9.5) 0.99 2.67 -61.86 2 8 -1 115 358.403 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-methyl-2-[2-[[2-(2-oxo-3-phenyl-imidazolidin-1-yl)acetyl]amino]thiazol-4-yl]acetamide N-methyl-2-[2-[[2-(2-oxo-3-pheny…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.55 5.48 -26.94 2 8 0 95 373.438 6 ↓
Hi High (pH 8-9.5) 1.36 4.15 -65.65 1 8 -1 101 372.43 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-oxo-3-(p-tolyl)imidazolidin-1-yl]-N-thiazol-2-yl-acetamide 2-[2-oxo-3-(p-tolyl)imidazolidin…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.47 7.4 -24.66 1 6 0 66 316.386 4 ↓
Hi High (pH 8-9.5) 2.29 6.06 -53.94 0 6 -1 72 315.378 4 ↓

Analogs

6359186
6359186

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-methylthiazol-2-yl)-2-[2-oxo-3-(p-tolyl)imidazolidin-1-yl]acetamide N-(4-methylthiazol-2-yl)-2-[2-ox…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 7.68 -19.61 1 6 0 66 330.413 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: ethyl ethyl

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.13 9.52 -23.89 1 8 0 92 402.476 8 ↓
Hi High (pH 8-9.5) 2.95 8.2 -60.41 0 8 -1 98 401.468 8 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N,N,4-trimethyl-2-[[2-[2-oxo-3-(p-tolyl)imidazolidin-1-yl]acetyl]amino]thiazole-5-carboxamide N,N,4-trimethyl-2-[[2-[2-oxo-3-(…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.37 7.92 -29.99 1 8 0 86 401.492 5 ↓
Hi High (pH 8-9.5) 2.19 6.38 -57.89 0 8 -1 92 400.484 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(5-methylthiazol-2-yl)-2-[2-oxo-3-(p-tolyl)imidazolidin-1-yl]acetamide N-(5-methylthiazol-2-yl)-2-[2-ox…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 8.23 -24.68 1 6 0 66 330.413 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(2-amino-2-oxo-ethyl)thiazol-2-yl]-2-[2-oxo-3-(p-tolyl)imidazolidin-1-yl]acetamide N-[4-(2-amino-2-oxo-ethyl)thiazo…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.62 4.68 -28.1 3 8 0 109 373.438 6 ↓
Hi High (pH 8-9.5) 1.44 3.34 -62.01 2 8 -1 115 372.43 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-[2-(methylamino)-2-oxo-ethyl]thiazol-2-yl]-2-[2-oxo-3-(p-tolyl)imidazolidin-1-yl]acetamide N-[4-[2-(methylamino)-2-oxo-ethy…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.00 6.15 -28.21 2 8 0 95 387.465 6 ↓
Hi High (pH 8-9.5) 1.81 4.83 -62.46 1 8 -1 101 386.457 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(4-fluorophenyl)-2-oxo-imidazolidin-1-yl]-N-thiazol-2-yl-acetamide 2-[3-(4-fluorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.19 6.79 -24.07 1 6 0 66 320.349 4 ↓
Hi High (pH 8-9.5) 2.00 5.45 -51.93 0 6 -1 72 319.341 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(4-fluorophenyl)-2-oxo-imidazolidin-1-yl]-N-(4-methylthiazol-2-yl)acetamide 2-[3-(4-fluorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.41 7.07 -19.52 1 6 0 66 334.376 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: ethyl ethyl

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 8.91 -23.65 1 8 0 92 406.439 8 ↓
Hi High (pH 8-9.5) 2.66 7.59 -57.94 0 8 -1 98 405.431 8 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[3-(4-fluorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]-N,N,4-trimethyl-thiazole-5-carboxami 2-[[2-[3-(4-fluorophenyl)-2-oxo-…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.08 7.34 -29.7 1 8 0 86 405.455 5 ↓
Hi High (pH 8-9.5) 1.90 5.81 -56.19 0 8 -1 92 404.447 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(4-fluorophenyl)-2-oxo-imidazolidin-1-yl]-N-(5-methylthiazol-2-yl)acetamide 2-[3-(4-fluorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.41 7.62 -24.24 1 6 0 66 334.376 4 ↓
Hi High (pH 8-9.5) 2.23 6.28 -54.11 0 6 -1 72 333.368 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(2-amino-2-oxo-ethyl)thiazol-2-yl]-2-[3-(4-fluorophenyl)-2-oxo-imidazolidin-1-yl]acetamide N-[4-(2-amino-2-oxo-ethyl)thiazo…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.34 4.07 -27.77 3 8 0 109 377.401 6 ↓
Hi High (pH 8-9.5) 1.15 2.74 -59.54 2 8 -1 115 376.393 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[[2-[3-(4-fluorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]thiazol-4-yl]-N-methyl-acetamide 2-[2-[[2-[3-(4-fluorophenyl)-2-o…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 5.55 -26.59 2 8 0 95 391.428 6 ↓
Hi High (pH 8-9.5) 1.53 4.22 -63.25 1 8 -1 101 390.42 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(2-fluorophenyl)-2-oxo-imidazolidin-1-yl]-N-(4-methylthiazol-2-yl)acetamide 2-[3-(2-fluorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.36 7.35 -20.13 1 6 0 66 334.376 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: ethyl ethyl

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.79 9.2 -24.46 1 8 0 92 406.439 8 ↓
Hi High (pH 8-9.5) 2.61 7.87 -60.07 0 8 -1 98 405.431 8 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[3-(2-fluorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]-N,N,4-trimethyl-thiazole-5-carboxami 2-[[2-[3-(2-fluorophenyl)-2-oxo-…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.04 7.64 -30.05 1 8 0 86 405.455 5 ↓
Hi High (pH 8-9.5) 1.85 6.09 -58.86 0 8 -1 92 404.447 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(2-fluorophenyl)-2-oxo-imidazolidin-1-yl]-N-(5-methylthiazol-2-yl)acetamide 2-[3-(2-fluorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.36 7.9 -25.02 1 6 0 66 334.376 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(2-amino-2-oxo-ethyl)thiazol-2-yl]-2-[3-(2-fluorophenyl)-2-oxo-imidazolidin-1-yl]acetamide N-[4-(2-amino-2-oxo-ethyl)thiazo…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.29 4.35 -28.65 3 8 0 109 377.401 6 ↓
Hi High (pH 8-9.5) 1.11 3.02 -63.04 2 8 -1 115 376.393 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[[2-[3-(2-fluorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]thiazol-4-yl]-N-methyl-acetamide 2-[2-[[2-[3-(2-fluorophenyl)-2-o…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.66 5.83 -27.53 2 8 0 95 391.428 6 ↓
Hi High (pH 8-9.5) 1.48 4.5 -65.35 1 8 -1 101 390.42 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(3-chlorophenyl)-2-oxo-imidazolidin-1-yl]-N-(4-methylthiazol-2-yl)acetamide 2-[3-(3-chlorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.90 7.52 -17.73 1 6 0 66 350.831 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: ethyl ethyl

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 9.37 -21.78 1 8 0 92 422.894 8 ↓
Hi High (pH 8-9.5) 3.15 8.04 -55.97 0 8 -1 98 421.886 8 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[3-(3-chlorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]-N,N,4-trimethyl-thiazole-5-carboxami 2-[[2-[3-(3-chlorophenyl)-2-oxo-…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.58 7.77 -28.38 1 8 0 86 421.91 5 ↓
Hi High (pH 8-9.5) 2.39 6.22 -54.1 0 8 -1 92 420.902 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(3-chlorophenyl)-2-oxo-imidazolidin-1-yl]-N-(5-methylthiazol-2-yl)acetamide 2-[3-(3-chlorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.90 8.07 -22.56 1 6 0 66 350.831 4 ↓
Hi High (pH 8-9.5) 2.72 6.73 -52.14 0 6 -1 72 349.823 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(2-amino-2-oxo-ethyl)thiazol-2-yl]-2-[3-(3-chlorophenyl)-2-oxo-imidazolidin-1-yl]acetamide N-[4-(2-amino-2-oxo-ethyl)thiazo…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 4.52 -25.91 3 8 0 109 393.856 6 ↓
Hi High (pH 8-9.5) 1.64 3.19 -58.26 2 8 -1 115 392.848 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[[2-[3-(3-chlorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]thiazol-4-yl]-N-methyl-acetamide 2-[2-[[2-[3-(3-chlorophenyl)-2-o…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.20 6 -24.85 2 8 0 95 407.883 6 ↓
Hi High (pH 8-9.5) 2.02 4.67 -61.26 1 8 -1 101 406.875 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(4-chlorophenyl)-2-oxo-imidazolidin-1-yl]-N-thiazol-2-yl-acetamide 2-[3-(4-chlorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 7.25 -23.61 1 6 0 66 336.804 4 ↓
Hi High (pH 8-9.5) 2.52 5.9 -51.5 0 6 -1 72 335.796 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(4-chlorophenyl)-2-oxo-imidazolidin-1-yl]-N-(4-methylthiazol-2-yl)acetamide 2-[3-(4-chlorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.92 7.52 -19.04 1 6 0 66 350.831 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: ethyl ethyl

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.36 9.37 -23.07 1 8 0 92 422.894 8 ↓
Hi High (pH 8-9.5) 3.17 8.04 -57.57 0 8 -1 98 421.886 8 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[3-(4-chlorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]-N,N,4-trimethyl-thiazole-5-carboxami 2-[[2-[3-(4-chlorophenyl)-2-oxo-…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.60 7.79 -29.22 1 8 0 86 421.91 5 ↓
Hi High (pH 8-9.5) 2.42 6.22 -55.72 0 8 -1 92 420.902 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(4-chlorophenyl)-2-oxo-imidazolidin-1-yl]-N-(5-methylthiazol-2-yl)acetamide 2-[3-(4-chlorophenyl)-2-oxo-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.92 8.07 -23.76 1 6 0 66 350.831 4 ↓
Hi High (pH 8-9.5) 2.74 6.73 -53.7 0 6 -1 72 349.823 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(2-amino-2-oxo-ethyl)thiazol-2-yl]-2-[3-(4-chlorophenyl)-2-oxo-imidazolidin-1-yl]acetamide N-[4-(2-amino-2-oxo-ethyl)thiazo…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.85 4.52 -27.22 3 8 0 109 393.856 6 ↓
Hi High (pH 8-9.5) 1.67 3.19 -59.24 2 8 -1 115 392.848 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[[2-[3-(4-chlorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]thiazol-4-yl]-N-methyl-acetamide 2-[2-[[2-[3-(4-chlorophenyl)-2-o…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.22 6 -26.03 2 8 0 95 407.883 6 ↓
Hi High (pH 8-9.5) 2.04 4.67 -62.92 1 8 -1 101 406.875 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(3,4-difluorophenyl)-2-oxo-imidazolidin-1-yl]-N-thiazol-2-yl-acetamide 2-[3-(3,4-difluorophenyl)-2-oxo-…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 6.85 -22.75 1 6 0 66 338.339 4 ↓
Hi High (pH 8-9.5) 2.10 5.51 -48.67 0 6 -1 72 337.331 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(3,4-difluorophenyl)-2-oxo-imidazolidin-1-yl]-N-(4-methylthiazol-2-yl)acetamide 2-[3-(3,4-difluorophenyl)-2-oxo-…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.50 7.13 -18.27 1 6 0 66 352.366 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: ethyl ethyl

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.93 8.97 -22.35 1 8 0 92 424.429 8 ↓
Hi High (pH 8-9.5) 2.75 7.64 -54.08 0 8 -1 98 423.421 8 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[3-(3,4-difluorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]-N,N,4-trimethyl-thiazole-5-carbo 2-[[2-[3-(3,4-difluorophenyl)-2-…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.18 7.37 -28.76 1 8 0 86 423.445 5 ↓
Hi High (pH 8-9.5) 1.99 5.83 -52.91 0 8 -1 92 422.437 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(3,4-difluorophenyl)-2-oxo-imidazolidin-1-yl]-N-(5-methylthiazol-2-yl)acetamide 2-[3-(3,4-difluorophenyl)-2-oxo-…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.50 7.68 -22.76 1 6 0 66 352.366 4 ↓
Hi High (pH 8-9.5) 2.32 6.33 -50.6 0 6 -1 72 351.358 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(2-amino-2-oxo-ethyl)thiazol-2-yl]-2-[3-(3,4-difluorophenyl)-2-oxo-imidazolidin-1-yl]acetamide N-[4-(2-amino-2-oxo-ethyl)thiazo…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.43 4.12 -26.35 3 8 0 109 395.391 6 ↓
Hi High (pH 8-9.5) 1.25 2.79 -56.47 2 8 -1 115 394.383 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[[2-[3-(3,4-difluorophenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]thiazol-4-yl]-N-methyl-acetami 2-[2-[[2-[3-(3,4-difluorophenyl)…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 5.6 -25.29 2 8 0 95 409.418 6 ↓
Hi High (pH 8-9.5) 1.62 4.27 -59.26 1 8 -1 101 408.41 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(4-methoxyphenyl)-2-oxo-imidazolidin-1-yl]-N-thiazol-2-yl-acetamide 2-[3-(4-methoxyphenyl)-2-oxo-imi…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.08 6.02 -24.97 1 7 0 75 332.385 5 ↓
Hi High (pH 8-9.5) 1.90 4.68 -53.5 0 7 -1 81 331.377 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(4-methoxyphenyl)-2-oxo-imidazolidin-1-yl]-N-(4-methylthiazol-2-yl)acetamide 2-[3-(4-methoxyphenyl)-2-oxo-imi…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 6.3 -21.08 1 7 0 75 346.412 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: ethyl ethyl

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.74 8.14 -25.11 1 9 0 101 418.475 9 ↓
Hi High (pH 8-9.5) 2.55 6.81 -61.08 0 9 -1 107 417.467 9 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[3-(4-methoxyphenyl)-2-oxo-imidazolidin-1-yl]acetyl]amino]-N,N,4-trimethyl-thiazole-5-carboxam 2-[[2-[3-(4-methoxyphenyl)-2-oxo…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.98 6.54 -31.25 1 9 0 95 417.491 6 ↓
Hi High (pH 8-9.5) 1.80 5.03 -58.78 0 9 -1 101 416.483 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[3-(4-methoxyphenyl)-2-oxo-imidazolidin-1-yl]-N-(5-methylthiazol-2-yl)acetamide 2-[3-(4-methoxyphenyl)-2-oxo-imi…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 6.85 -25.95 1 7 0 75 346.412 5 ↓

Parameters Provided:

ring.id = 558429
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 558429 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

Permalink

//zinc12.docking.org/results/combination?ring.id=558429&filter.purchasability=annotated

Embed Link to Results