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ZINC Item

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37325915

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-(2-chloro-4-fluoro-phenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-chloro-4-fluoro-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.99	7.47	-49.71	0	5	-1	75	309.704	3	↓ MOL2 SDF SMILES Flexibase

37325916

Analogs

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Popular Name: 3-[1-(3-bromophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(3-bromophenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.53	7.98	-48.35	0	5	-1	75	350.192	4	↓ MOL2 SDF SMILES Flexibase

37325917

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-(3-bromophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3-bromophenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.01	7.27	-50.82	0	5	-1	75	336.165	3	↓ MOL2 SDF SMILES Flexibase

37325918

Analogs

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Popular Name: 3-[1-(3-chlorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(3-chlorophenyl)-4,6-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	7.88	-48.45	0	5	-1	75	305.741	4	↓ MOL2 SDF SMILES Flexibase

37325919

Analogs

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Popular Name: 2-[1-(3-chlorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3-chlorophenyl)-4,6-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.88	7.17	-51.01	0	5	-1	75	291.714	3	↓ MOL2 SDF SMILES Flexibase

37325920

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[1-(3-fluorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(3-fluorophenyl)-4,6-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.88	7.43	-49.08	0	5	-1	75	289.286	4	↓ MOL2 SDF SMILES Flexibase

37325921

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[1-(4-chlorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(4-chlorophenyl)-4,6-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.21	7.89	-46.6	0	5	-1	75	305.741	4	↓ MOL2 SDF SMILES Flexibase

37325922

Analogs

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Popular Name: 2-[1-(4-chlorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(4-chlorophenyl)-4,6-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.69	7.18	-48.07	0	5	-1	75	291.714	3	↓ MOL2 SDF SMILES Flexibase

37325925

Analogs

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Popular Name: 2-[1-(2,5-dimethylphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2,5-dimethylphenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.26	8.11	-52.29	0	5	-1	75	285.323	3	↓ MOL2 SDF SMILES Flexibase

37325934

Analogs

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Popular Name: 2-[1-(2-methoxyphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-methoxyphenyl)-4,6-dimet…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.23	6.06	-56.15	0	6	-1	84	287.295	4	↓ MOL2 SDF SMILES Flexibase

37325935

Analogs

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Popular Name: 2-[1-(3,4-dichlorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3,4-dichlorophenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.51	7.63	-48.02	0	5	-1	75	326.159	3	↓ MOL2 SDF SMILES Flexibase

37325936

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-(2,5-dichlorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2,5-dichlorophenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.72	7.91	-49.94	0	5	-1	75	326.159	3	↓ MOL2 SDF SMILES Flexibase

37325937

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-(2,4-dichlorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2,4-dichlorophenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.51	7.9	-49.67	0	5	-1	75	326.159	3	↓ MOL2 SDF SMILES Flexibase

37325939

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-(3,5-dichlorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3,5-dichlorophenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.72	7.68	-46.69	0	5	-1	75	326.159	3	↓ MOL2 SDF SMILES Flexibase

37325941

Analogs

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Popular Name: 2-[1-(3-chloro-4-methyl-phenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3-chloro-4-methyl-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.28	7.72	-48.38	0	5	-1	75	305.741	3	↓ MOL2 SDF SMILES Flexibase

37325950

Analogs

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Popular Name: 2-[1-(2,5-difluorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2,5-difluorophenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.69	6.83	-52.34	0	5	-1	75	293.249	3	↓ MOL2 SDF SMILES Flexibase

37325951

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[4,6-dimethyl-1-(4-methylsulfanylphenyl)-2-oxo-pyrimidin-5-yl]acetic 2-[4,6-dimethyl-1-(4-methylsulfa…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.45	7.68	-49.66	0	5	-1	75	303.363	4	↓ MOL2 SDF SMILES Flexibase

37325952

Analogs

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Popular Name: 2-[1-(4-bromo-2-fluoro-phenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(4-bromo-2-fluoro-phenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.13	7.39	-51.66	0	5	-1	75	354.155	3	↓ MOL2 SDF SMILES Flexibase

37325953

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-(2-bromo-4-methyl-phenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-bromo-4-methyl-phenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.41	8.21	-50	0	5	-1	75	350.192	3	↓ MOL2 SDF SMILES Flexibase

37325962

Analogs

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Popular Name: 3-[1-(3-iodophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(3-iodophenyl)-4,6-dimethyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	8.46	-48.15	0	5	-1	75	397.192	4	↓ MOL2 SDF SMILES Flexibase

37325963

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[1-(2-iodophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(2-iodophenyl)-4,6-dimethyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.78	8.79	-49.66	0	5	-1	75	397.192	4	↓ MOL2 SDF SMILES Flexibase

37325964

Analogs

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Popular Name: 2-[1-(2-iodophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-iodophenyl)-4,6-dimethyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.26	8.08	-51.38	0	5	-1	75	383.165	3	↓ MOL2 SDF SMILES Flexibase

37325965

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-(2,6-difluorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2,6-difluorophenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.67	6.9	-57.23	0	5	-1	75	293.249	3	↓ MOL2 SDF SMILES Flexibase

37325966

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[1-(4-iodophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(4-iodophenyl)-4,6-dimethyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.61	8.47	-46.3	0	5	-1	75	397.192	4	↓ MOL2 SDF SMILES Flexibase

37325967

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-(4-iodophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(4-iodophenyl)-4,6-dimethyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.10	7.76	-47.68	0	5	-1	75	383.165	3	↓ MOL2 SDF SMILES Flexibase

37325976

Analogs

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Popular Name: 3-[1-(4-fluorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(4-fluorophenyl)-4,6-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.69	7.43	-46.81	0	5	-1	75	289.286	4	↓ MOL2 SDF SMILES Flexibase

37325979

Analogs

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Popular Name: 2-[1-(2-ethylphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-ethylphenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.09	7.93	-51.33	0	5	-1	75	285.323	4	↓ MOL2 SDF SMILES Flexibase

37325980

Analogs

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Popular Name: 2-[1-(4-fluoro-2-methyl-phenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(4-fluoro-2-methyl-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.76	7.62	-47.85	0	5	-1	75	289.286	3	↓ MOL2 SDF SMILES Flexibase

37325984

Analogs

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Popular Name: 2-[1-(2-fluorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-fluorophenyl)-4,6-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.34	6.77	-56.27	0	5	-1	75	275.259	3	↓ MOL2 SDF SMILES Flexibase

37325987

Analogs

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Popular Name: 2-[1-(3,4-difluorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3,4-difluorophenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.48	6.78	-48.86	0	5	-1	75	293.249	3	↓ MOL2 SDF SMILES Flexibase

37325989

Analogs

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Popular Name: 2-[1-(4-ethylphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(4-ethylphenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.93	8.06	-50.51	0	5	-1	75	285.323	4	↓ MOL2 SDF SMILES Flexibase

37325990

Analogs

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Popular Name: 2-[1-(2-cyanophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-cyanophenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.93	7.25	-61.6	0	6	-1	99	282.279	3	↓ MOL2 SDF SMILES Flexibase

37325999

Analogs

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Popular Name: 2-[1-(3-cyanophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3-cyanophenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.96	7.05	-50.11	0	6	-1	99	282.279	3	↓ MOL2 SDF SMILES Flexibase

37326004

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-(4,6-dimethyl-2-oxo-1-phenyl-pyrimidin-5-yl)propanoic 3-(4,6-dimethyl-2-oxo-1-phenyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.53	7.37	-49.24	0	5	-1	75	271.296	4	↓ MOL2 SDF SMILES Flexibase

37326005

Analogs

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Popular Name: 2-[1-(2,4-dimethylphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2,4-dimethylphenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	8.22	-51.32	0	5	-1	75	285.323	3	↓ MOL2 SDF SMILES Flexibase

37326006

Analogs

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Popular Name: 2-[1-(3,4-dimethylphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3,4-dimethylphenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	7.84	-51.52	0	5	-1	75	285.323	3	↓ MOL2 SDF SMILES Flexibase

37326007

Analogs

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Popular Name: 2-[1-(2,3-dimethylphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2,3-dimethylphenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.03	7.99	-51.99	0	5	-1	75	285.323	3	↓ MOL2 SDF SMILES Flexibase

37326008

Analogs

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Popular Name: 2-[1-(2-chlorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-chlorophenyl)-4,6-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.85	7.39	-53.75	0	5	-1	75	291.714	3	↓ MOL2 SDF SMILES Flexibase

37326012

Analogs

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Popular Name: 2-[1-(3-ethylphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3-ethylphenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.12	8.05	-50.99	0	5	-1	75	285.323	4	↓ MOL2 SDF SMILES Flexibase

37326023

Analogs

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Popular Name: 2-[1-(3,5-difluorophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3,5-difluorophenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.69	6.8	-46.87	0	5	-1	75	293.249	3	↓ MOL2 SDF SMILES Flexibase

37326024

Analogs

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Popular Name: 2-[1-(3,5-dimethylphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3,5-dimethylphenyl)-4,6-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.26	7.94	-51.44	0	5	-1	75	285.323	3	↓ MOL2 SDF SMILES Flexibase

37326025

Analogs

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Popular Name: 2-[1-(5-fluoro-2-methyl-phenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(5-fluoro-2-methyl-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	7.62	-51.71	0	5	-1	75	289.286	3	↓ MOL2 SDF SMILES Flexibase

37326033

Analogs

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Popular Name: 3-[1-(4-bromophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(4-bromophenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.34	7.99	-46.49	0	5	-1	75	350.192	4	↓ MOL2 SDF SMILES Flexibase

37326034

Analogs

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Popular Name: 3-[4,6-dimethyl-1-(m-tolyl)-2-oxo-pyrimidin-5-yl]propanoic 3-[4,6-dimethyl-1-(m-tolyl)-2-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.17	8.06	-49.15	0	5	-1	75	285.323	4	↓ MOL2 SDF SMILES Flexibase

37326035

Analogs

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Popular Name: 2-[4,6-dimethyl-1-(m-tolyl)-2-oxo-pyrimidin-5-yl]acetic 2-[4,6-dimethyl-1-(m-tolyl)-2-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.65	7.28	-51.07	0	5	-1	75	271.296	3	↓ MOL2 SDF SMILES Flexibase

37326036

Analogs

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Popular Name: 2-[1-(3-methoxyphenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(3-methoxyphenyl)-4,6-dimet…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.26	5.96	-54.54	0	6	-1	84	287.295	4	↓ MOL2 SDF SMILES Flexibase

37326037

Analogs

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Popular Name: 2-[4,6-dimethyl-2-oxo-1-(p-tolyl)pyrimidin-5-yl]acetic 2-[4,6-dimethyl-2-oxo-1-(p-tolyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.46	7.29	-50.81	0	5	-1	75	271.296	3	↓ MOL2 SDF SMILES Flexibase

37326038

Analogs

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Popular Name: 3-[1-(2-bromophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]propanoic 3-[1-(2-bromophenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.50	8.28	-50.52	0	5	-1	75	350.192	4	↓ MOL2 SDF SMILES Flexibase

37326039

Analogs

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Popular Name: 2-[1-(2-bromophenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-bromophenyl)-4,6-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.99	7.57	-53.1	0	5	-1	75	336.165	3	↓ MOL2 SDF SMILES Flexibase

37326043

Analogs

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Popular Name: 2-[1-(2-fluoro-4-methyl-phenyl)-4,6-dimethyl-2-oxo-pyrimidin-5-yl]acetic 2-[1-(2-fluoro-4-methyl-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.76	7.42	-51.81	0	5	-1	75	289.286	3	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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