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Popular Name: 1-[(1S)-1-(4-fluorophenyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(4-fluorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.55 6.79 -33.3 2 2 1 29 207.272 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(4-fluorophenyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(4-fluorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.55 7.08 -31.63 2 2 1 29 207.272 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(2-chlorophenyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(2-chlorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.01 6.75 -28.95 2 2 1 29 223.727 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(2-chlorophenyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(2-chlorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.01 7.49 -28.14 2 2 1 29 223.727 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(3-chlorophenyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(3-chlorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 7.23 -31.21 2 2 1 29 223.727 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(3-chlorophenyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(3-chlorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 7.52 -29.76 2 2 1 29 223.727 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(4-chlorophenyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(4-chlorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.06 7.24 -32.43 2 2 1 29 223.727 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(4-chlorophenyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(4-chlorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.06 7.53 -30.74 2 2 1 29 223.727 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(4-bromophenyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(4-bromophenyl)ethyl]p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.19 7.34 -32.51 2 2 1 29 268.178 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(4-bromophenyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(4-bromophenyl)ethyl]p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.19 7.64 -30.81 2 2 1 29 268.178 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(o-tolyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(o-tolyl)ethyl]pyrroli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.78 7.53 -28.14 2 2 1 29 203.309 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(o-tolyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(o-tolyl)ethyl]pyrroli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.78 6.92 -27.94 2 2 1 29 203.309 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(2-fluorophenyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(2-fluorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.50 6.42 -29.54 2 2 1 29 207.272 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(2-fluorophenyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(2-fluorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.50 7.11 -28.82 2 2 1 29 207.272 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(3-fluorophenyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(3-fluorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 6.79 -31.94 2 2 1 29 207.272 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(3-fluorophenyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(3-fluorophenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 7.08 -30.6 2 2 1 29 207.272 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(p-tolyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(p-tolyl)ethyl]pyrroli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 7.7 -27.87 2 2 1 29 203.309 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(p-tolyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(p-tolyl)ethyl]pyrroli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 7.42 -29.7 2 2 1 29 203.309 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(3-bromophenyl)ethyl]pyrrolidin-2-imine 1-[(1S)-1-(3-bromophenyl)ethyl]p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 7.33 -31.19 2 2 1 29 268.178 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(3-bromophenyl)ethyl]pyrrolidin-2-imine 1-[(1R)-1-(3-bromophenyl)ethyl]p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 7.63 -29.83 2 2 1 29 268.178 2 ↓

Analogs

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Popular Name: 1-[(3,4-difluorophenyl)methyl]pyrrolidin-2-imine 1-[(3,4-difluorophenyl)methyl]py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.08 6.65 -36.83 2 2 1 29 211.235 2 ↓

Analogs

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Popular Name: 1-[(3-bromophenyl)methyl]pyrrolidin-2-imine 1-[(3-bromophenyl)methyl]pyrroli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.61 7.14 -31.17 2 2 1 29 254.151 2 ↓

Analogs

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Popular Name: 1-[(2-bromophenyl)methyl]pyrrolidin-2-imine 1-[(2-bromophenyl)methyl]pyrroli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.58 6.74 -30.21 2 2 1 29 254.151 2 ↓

Parameters Provided:

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