UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 4-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-ylsulfamoyl)benzoic 4-(5,6-dihydro-4H-cyclopenta[d]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 5.8 -52.79 1 6 -1 102 323.375 3 ↓
Mid Mid (pH 6-8) 2.64 5.26 -99.89 0 6 -2 101 322.367 4 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 3.11 -13.94 3 5 0 88 295.389 2 ↓
Mid Mid (pH 6-8) 1.78 2.57 -54.23 2 5 -1 87 294.381 3 ↓

Analogs

44257872
44257872

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Popular Name: 4-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 4-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 3.11 -14.09 3 5 0 88 295.389 2 ↓
Mid Mid (pH 6-8) 1.80 2.57 -54.55 2 5 -1 87 294.381 3 ↓
Lo Low (pH 4.5-6) 2.73 2.96 -57.29 4 5 1 90 296.397 2 ↓

Analogs

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Popular Name: 2-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 2-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 3.48 -13.44 3 5 0 88 295.389 2 ↓
Mid Mid (pH 6-8) 2.16 2.94 -52.02 2 5 -1 87 294.381 3 ↓

Analogs

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Popular Name: 2-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-fluoro-benzenesulfonamide 2-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 3.54 -11.01 3 5 0 88 313.379 2 ↓
Mid Mid (pH 6-8) 2.30 2.99 -45.79 2 5 -1 87 312.371 3 ↓

Analogs

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Popular Name: 5-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2-methyl-benzenesulfonamide 5-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.11 3.89 -13.91 3 5 0 88 309.416 2 ↓
Mid Mid (pH 6-8) 2.18 3.34 -54.05 2 5 -1 87 308.408 3 ↓

Analogs

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Popular Name: 5-amino-2-chloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 5-amino-2-chloro-N-(5,6-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.34 3.67 -14.51 3 5 0 88 329.834 2 ↓
Mid Mid (pH 6-8) 2.41 3.13 -54.23 2 5 -1 87 328.826 3 ↓

Analogs

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Popular Name: 4-amino-2-chloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 4-amino-2-chloro-N-(5,6-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.34 3.67 -14.66 3 5 0 88 329.834 2 ↓
Mid Mid (pH 6-8) 2.41 3.14 -54.58 2 5 -1 87 328.826 3 ↓

Analogs

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Popular Name: 3-amino-4-chloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 3-amino-4-chloro-N-(5,6-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.74 3.69 -11.51 3 5 0 88 329.834 2 ↓
Mid Mid (pH 6-8) 2.82 3.15 -48.5 2 5 -1 87 328.826 3 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-hydroxy-benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.85 0.38 -13.89 4 6 0 109 311.388 2 ↓
Mid Mid (pH 6-8) 1.92 -0.16 -52.43 3 6 -1 107 310.38 3 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-fluoro-benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 3.2 -11.54 3 5 0 88 313.379 2 ↓
Mid Mid (pH 6-8) 2.30 2.66 -47.91 2 5 -1 87 312.371 3 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-methyl-benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.51 3.89 -14.08 3 5 0 88 309.416 2 ↓
Mid Mid (pH 6-8) 2.59 3.35 -54.77 2 5 -1 87 308.408 3 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-methoxy-benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 2.53 -13.59 3 6 0 98 325.415 3 ↓
Mid Mid (pH 6-8) 2.19 1.99 -52.55 2 6 -1 96 324.407 4 ↓

Analogs

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Popular Name: 3-amino-5-chloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-methyl-benzenesulfonamide 3-amino-5-chloro-N-(5,6-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.12 4.32 -12.94 3 5 0 88 343.861 2 ↓
Mid Mid (pH 6-8) 3.19 3.78 -51.59 2 5 -1 87 342.853 3 ↓

Analogs

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Popular Name: 5-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2-methoxy-benzenesulfonamide 5-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 2.88 -17.3 3 6 0 98 325.415 3 ↓
Mid Mid (pH 6-8) 1.79 2.35 -60.13 2 6 -1 96 324.407 4 ↓

Analogs

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Popular Name: 5-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2,4-difluoro-benzenesulfonamide 5-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.32 3.26 -12.6 3 5 0 88 331.369 2 ↓
Mid Mid (pH 6-8) 2.39 2.72 -50.15 2 5 -1 87 330.361 3 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4,5-dimethyl-benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.89 4.43 -14.5 3 5 0 88 323.443 2 ↓
Mid Mid (pH 6-8) 2.96 3.89 -55.94 2 5 -1 87 322.435 3 ↓

Analogs

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Popular Name: 5-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2,3-dimethyl-benzenesulfonamide 5-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.48 4.45 -14.32 3 5 0 88 323.443 2 ↓
Mid Mid (pH 6-8) 2.56 3.93 -55.05 2 5 -1 87 322.435 3 ↓

Analogs

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Popular Name: 2-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-methoxy-benzenesulfonamide 2-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 2.77 -13.1 3 6 0 98 325.415 3 ↓
Mid Mid (pH 6-8) 2.19 2.22 -50.11 2 6 -1 96 324.407 4 ↓

Analogs

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Popular Name: 2-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4,5-dimethyl-benzenesulfonamide 2-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.89 4.69 -13.77 3 5 0 88 323.443 2 ↓
Mid Mid (pH 6-8) 2.96 4.15 -53.24 2 5 -1 87 322.435 3 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2-methyl-benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.49 3.98 -13.92 3 5 0 88 309.416 2 ↓
Mid Mid (pH 6-8) 2.56 3.44 -53.84 2 5 -1 87 308.408 3 ↓

Analogs

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Popular Name: 2-amino-4-chloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 2-amino-4-chloro-N-(5,6-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.74 4 -11.01 3 5 0 88 329.834 2 ↓
Mid Mid (pH 6-8) 2.82 3.45 -46.44 2 5 -1 87 328.826 3 ↓

Analogs

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Popular Name: 5-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2-fluoro-benzenesulfonamide 5-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.82 3.17 -15.99 3 5 0 88 313.379 2 ↓
Mid Mid (pH 6-8) 1.89 2.63 -57.57 2 5 -1 87 312.371 3 ↓

Analogs

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Popular Name: 5-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2-ethyl-benzenesulfonamide 5-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.57 4.84 -13.45 3 5 0 88 323.443 3 ↓
Mid Mid (pH 6-8) 2.64 4.32 -52.69 2 5 -1 87 322.435 4 ↓

Analogs

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Popular Name: 2-amino-4,6-dichloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 2-amino-4,6-dichloro-N-(5,6-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.35 4.77 -10.67 3 5 0 88 364.279 2 ↓
Mid Mid (pH 6-8) 3.42 4.22 -45.48 2 5 -1 87 363.271 3 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-5-methyl-benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.11 3.77 -14.02 3 5 0 88 309.416 2 ↓
Mid Mid (pH 6-8) 2.18 3.23 -54.81 2 5 -1 87 308.408 3 ↓

Analogs

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Popular Name: 4-amino-2-bromo-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 4-amino-2-bromo-N-(5,6-dihydro-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 3.83 -14.38 3 5 0 88 374.285 2 ↓
Mid Mid (pH 6-8) 2.54 3.28 -53.79 2 5 -1 87 373.277 3 ↓

Analogs

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Popular Name: 4-amino-2-cyano-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 4-amino-2-cyano-N-(5,6-dihydro-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.41 3.4 -17.92 3 6 0 112 320.399 2 ↓
Mid Mid (pH 6-8) 1.49 2.85 -59.35 2 6 -1 111 319.391 3 ↓

Analogs

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Popular Name: 2-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-methyl-benzenesulfonamide 2-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.51 4.14 -13.33 3 5 0 88 309.416 2 ↓
Mid Mid (pH 6-8) 2.59 3.59 -52.08 2 5 -1 87 308.408 3 ↓

Analogs

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Popular Name: 4-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2-methyl-benzenesulfonamide 4-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.11 3.88 -14.06 3 5 0 88 309.416 2 ↓
Mid Mid (pH 6-8) 2.18 3.33 -54.29 2 5 -1 87 308.408 3 ↓

Analogs

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Popular Name: 6-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2,3-dimethyl-benzenesulfonamide 6-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.89 5 -12.51 3 5 0 88 323.443 2 ↓
Mid Mid (pH 6-8) 2.96 4.47 -51.37 2 5 -1 87 322.435 3 ↓

Analogs

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Popular Name: 4-amino-2,6-dichloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 4-amino-2,6-dichloro-N-(5,6-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.94 4.43 -14.7 3 5 0 88 364.279 2 ↓
Mid Mid (pH 6-8) 3.01 3.88 -53.91 2 5 -1 87 363.271 3 ↓

Analogs

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Popular Name: 5-amino-3-chloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2-fluoro-benzenesulfonamide 5-amino-3-chloro-N-(5,6-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.43 3.67 -14.8 3 5 0 88 347.824 2 ↓
Mid Mid (pH 6-8) 2.50 3.13 -54.06 2 5 -1 87 346.816 3 ↓

Analogs

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Popular Name: 4-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2-methoxy-benzenesulfonamide 4-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 2.88 -17.56 3 6 0 98 325.415 3 ↓
Mid Mid (pH 6-8) 1.79 2.35 -60.56 2 6 -1 96 324.407 4 ↓

Analogs

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Popular Name: 2-amino-4-bromo-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 2-amino-4-bromo-N-(5,6-dihydro-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.87 4.1 -11 3 5 0 88 374.285 2 ↓
Mid Mid (pH 6-8) 2.95 3.55 -46.35 2 5 -1 87 373.277 3 ↓

Analogs

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Popular Name: 4-amino-2,6-dibromo-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 4-amino-2,6-dibromo-N-(5,6-dihyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.20 4.7 -14.04 3 5 0 88 453.181 2 ↓
Mid Mid (pH 6-8) 3.28 4.17 -52.19 2 5 -1 87 452.173 3 ↓

Analogs

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Popular Name: 2-amino-4,6-dibromo-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 2-amino-4,6-dibromo-N-(5,6-dihyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.61 5.04 -10.21 3 5 0 88 453.181 2 ↓
Mid Mid (pH 6-8) 3.68 4.49 -44.67 2 5 -1 87 452.173 3 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2,6-dimethyl-benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.89 4.9 -13.36 3 5 0 88 323.443 2 ↓
Mid Mid (pH 6-8) 2.96 4.36 -53.43 2 5 -1 87 322.435 3 ↓

Analogs

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Popular Name: 3-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-ethyl-benzenesulfonamide 3-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.98 4.63 -13.74 3 5 0 88 323.443 3 ↓
Mid Mid (pH 6-8) 3.05 4.1 -54.33 2 5 -1 87 322.435 4 ↓

Analogs

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Popular Name: 2-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-6-methyl-benzenesulfonamide 2-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.49 4.46 -12.4 3 5 0 88 309.416 2 ↓
Mid Mid (pH 6-8) 2.56 3.92 -50.82 2 5 -1 87 308.408 3 ↓

Analogs

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Popular Name: 4-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-2,6-difluoro-benzenesulfonamide 4-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 3.38 -17.73 3 5 0 88 331.369 2 ↓
Mid Mid (pH 6-8) 1.99 2.84 -60.14 2 5 -1 87 330.361 3 ↓

Analogs

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Popular Name: 2-amino-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-5-fluoro-benzenesulfonamide 2-amino-N-(5,6-dihydro-4H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 3.54 -13.24 3 5 0 88 313.379 2 ↓
Mid Mid (pH 6-8) 2.30 2.99 -49.68 2 5 -1 87 312.371 3 ↓

Analogs

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Popular Name: 2-amino-5-chloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 2-amino-5-chloro-N-(5,6-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.74 3.99 -12.61 3 5 0 88 329.834 2 ↓
Mid Mid (pH 6-8) 2.82 3.45 -49.18 2 5 -1 87 328.826 3 ↓

Analogs

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Popular Name: 2-amino-5-bromo-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 2-amino-5-bromo-N-(5,6-dihydro-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.87 4.1 -12.52 3 5 0 88 374.285 2 ↓
Mid Mid (pH 6-8) 2.95 3.55 -49 2 5 -1 87 373.277 3 ↓

Analogs

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Popular Name: 5-amino-2-chloro-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-4-fluoro-benzenesulfonamide 5-amino-2-chloro-N-(5,6-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.83 3.76 -11.41 3 5 0 88 347.824 2 ↓
Mid Mid (pH 6-8) 2.91 3.23 -47.4 2 5 -1 87 346.816 3 ↓

Analogs

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Popular Name: 3-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-ylsulfamoyl)benzenecarbothioamide 3-(5,6-dihydro-4H-cyclopenta[d]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.43 4.46 -24.25 3 5 0 88 339.467 3 ↓
Mid Mid (pH 6-8) 2.50 3.92 -65 2 5 -1 87 338.459 4 ↓

Analogs

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Popular Name: 4-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-ylsulfamoyl)benzenecarbothioamide 4-(5,6-dihydro-4H-cyclopenta[d]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 4.46 -19.36 3 5 0 88 339.467 3 ↓
Mid Mid (pH 6-8) 2.52 3.92 -54.2 2 5 -1 87 338.459 4 ↓

Analogs

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Popular Name: 2-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-ylsulfamoyl)benzenecarbothioamide 2-(5,6-dihydro-4H-cyclopenta[d]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.40 4.63 -17.95 3 5 0 88 339.467 3 ↓
Mid Mid (pH 6-8) 2.48 4.09 -57.09 2 5 -1 87 338.459 4 ↓

Analogs

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Popular Name: 3-[(1S)-1-aminoethyl]-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 3-[(1S)-1-aminoethyl]-N-(5,6-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.50 3.99 -56.3 4 5 1 90 324.451 3 ↓
Mid Mid (pH 6-8) 0.57 3.44 -82.74 3 5 0 89 323.443 4 ↓

Analogs

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Popular Name: 3-[(1R)-1-aminoethyl]-N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzenesulfonamide 3-[(1R)-1-aminoethyl]-N-(5,6-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.50 3.98 -55.97 4 5 1 90 324.451 3 ↓
Mid Mid (pH 6-8) 0.57 3.44 -82.89 3 5 0 89 323.443 4 ↓

Parameters Provided:

ring.id = 581294
filter.purchasability = annotated
page.format = targets
page.num = 1

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SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 581294 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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