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Analogs

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Popular Name: N'-cyclopropyl-N-(4-methyl-3-nitro-phenyl)ethane-1,2-diamine N'-cyclopropyl-N-(4-methyl-3-nit…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 6.26 -50.39 3 5 1 74 236.295 6 ↓

Analogs

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Popular Name: N-cyclopropyl-N'-(4-fluorophenyl)-N-methyl-ethane-1,2-diamine N-cyclopropyl-N'-(4-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 6.87 -39.03 2 2 1 16 209.288 5 ↓
Hi High (pH 8-9.5) 2.35 4.41 -3.3 1 2 0 15 208.28 5 ↓

Analogs

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Popular Name: N'-(2-bromophenyl)-N-cyclopropyl-N-methyl-ethane-1,2-diamine N'-(2-bromophenyl)-N-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.95 7.54 -35.85 2 2 1 16 270.194 5 ↓
Hi High (pH 8-9.5) 2.95 5.22 -2.37 1 2 0 15 269.186 5 ↓

Analogs

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Popular Name: N'-(2-chlorophenyl)-N-cyclopropyl-N-methyl-ethane-1,2-diamine N'-(2-chlorophenyl)-N-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.82 7.41 -35.75 2 2 1 16 225.743 5 ↓
Hi High (pH 8-9.5) 2.82 5.09 -2.37 1 2 0 15 224.735 5 ↓

Analogs

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Popular Name: N'-cyclopropyl-N'-methyl-N-(m-tolyl)ethane-1,2-diamine N'-cyclopropyl-N'-methyl-N-(m-to…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 7.49 -35.43 2 2 1 16 205.325 5 ↓
Hi High (pH 8-9.5) 2.62 5.17 -2.58 1 2 0 15 204.317 5 ↓

Analogs

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Popular Name: N'-cyclopropyl-N'-methyl-N-(p-tolyl)ethane-1,2-diamine N'-cyclopropyl-N'-methyl-N-(p-to…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.64 7.48 -35.23 2 2 1 16 205.325 5 ↓
Hi High (pH 8-9.5) 2.64 5.02 -2.53 1 2 0 15 204.317 5 ↓

Analogs

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Popular Name: N'-(4-chlorophenyl)-N-cyclopropyl-N-methyl-ethane-1,2-diamine N'-(4-chlorophenyl)-N-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 7.32 -37.92 2 2 1 16 225.743 5 ↓
Hi High (pH 8-9.5) 2.87 4.86 -2.61 1 2 0 15 224.735 5 ↓

Analogs

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Popular Name: N-cyclopropyl-N'-(2-fluorophenyl)-N-methyl-ethane-1,2-diamine N-cyclopropyl-N'-(2-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.31 6.91 -36.57 2 2 1 16 209.288 5 ↓
Hi High (pH 8-9.5) 2.31 4.59 -3.09 1 2 0 15 208.28 5 ↓

Analogs

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Popular Name: N'-(3-chlorophenyl)-N-cyclopropyl-N-methyl-ethane-1,2-diamine N'-(3-chlorophenyl)-N-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.85 7.34 -37.79 2 2 1 16 225.743 5 ↓
Hi High (pH 8-9.5) 2.85 5.02 -2.44 1 2 0 15 224.735 5 ↓

Analogs

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Popular Name: N-cyclopropyl-N'-(3-fluorophenyl)-N-methyl-ethane-1,2-diamine N-cyclopropyl-N'-(3-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 6.89 -38.98 2 2 1 16 209.288 5 ↓
Hi High (pH 8-9.5) 2.33 4.57 -3.04 1 2 0 15 208.28 5 ↓

Analogs

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Popular Name: N'-(3-bromophenyl)-N-cyclopropyl-N-methyl-ethane-1,2-diamine N'-(3-bromophenyl)-N-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 7.44 -37.82 2 2 1 16 270.194 5 ↓
Hi High (pH 8-9.5) 2.98 5.12 -2.35 1 2 0 15 269.186 5 ↓

Analogs

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Popular Name: N'-cyclopropyl-N'-methyl-N-(o-tolyl)ethane-1,2-diamine N'-cyclopropyl-N'-methyl-N-(o-to…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.59 7.62 -35.85 2 2 1 16 205.325 5 ↓
Hi High (pH 8-9.5) 2.59 5.3 -2.55 1 2 0 15 204.317 5 ↓

Analogs

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Popular Name: N'-(4-bromophenyl)-N-cyclopropyl-N-methyl-ethane-1,2-diamine N'-(4-bromophenyl)-N-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.00 7.42 -38.03 2 2 1 16 270.194 5 ↓
Hi High (pH 8-9.5) 3.00 4.97 -2.57 1 2 0 15 269.186 5 ↓

Analogs

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Popular Name: N-cyclopropyl-N-ethyl-N'-(4-fluorophenyl)ethane-1,2-diamine N-cyclopropyl-N-ethyl-N'-(4-fluo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 7.53 -37.86 2 2 1 16 223.315 6 ↓
Hi High (pH 8-9.5) 2.73 5.21 -3.12 1 2 0 15 222.307 6 ↓

Analogs

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Popular Name: N'-(2-bromophenyl)-N-cyclopropyl-N-ethyl-ethane-1,2-diamine N'-(2-bromophenyl)-N-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 8.18 -34.45 2 2 1 16 284.221 6 ↓
Hi High (pH 8-9.5) 3.33 5.86 -2.22 1 2 0 15 283.213 6 ↓

Analogs

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Popular Name: N'-(2-chlorophenyl)-N-cyclopropyl-N-ethyl-ethane-1,2-diamine N'-(2-chlorophenyl)-N-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.20 8.06 -34.4 2 2 1 16 239.77 6 ↓
Hi High (pH 8-9.5) 3.20 5.74 -2.21 1 2 0 15 238.762 6 ↓

Analogs

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Popular Name: N-cyclopropyl-N-ethyl-N'-(m-tolyl)ethane-1,2-diamine N-cyclopropyl-N-ethyl-N'-(m-toly…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.99 8.12 -34.22 2 2 1 16 219.352 6 ↓
Hi High (pH 8-9.5) 2.99 5.81 -2.45 1 2 0 15 218.344 6 ↓

Analogs

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Popular Name: N-cyclopropyl-N-ethyl-N'-(p-tolyl)ethane-1,2-diamine N-cyclopropyl-N-ethyl-N'-(p-toly…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 8.13 -34.15 2 2 1 16 219.352 6 ↓
Hi High (pH 8-9.5) 3.02 5.82 -2.32 1 2 0 15 218.344 6 ↓

Analogs

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Popular Name: N'-(4-chlorophenyl)-N-cyclopropyl-N-ethyl-ethane-1,2-diamine N'-(4-chlorophenyl)-N-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 7.98 -36.81 2 2 1 16 239.77 6 ↓
Hi High (pH 8-9.5) 3.24 5.66 -2.37 1 2 0 15 238.762 6 ↓

Analogs

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Popular Name: N-cyclopropyl-N-ethyl-N'-(2-fluorophenyl)ethane-1,2-diamine N-cyclopropyl-N-ethyl-N'-(2-fluo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.68 7.56 -35.17 2 2 1 16 223.315 6 ↓
Hi High (pH 8-9.5) 2.68 5.24 -2.95 1 2 0 15 222.307 6 ↓

Analogs

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Popular Name: N'-(3-chlorophenyl)-N-cyclopropyl-N-ethyl-ethane-1,2-diamine N'-(3-chlorophenyl)-N-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.22 7.98 -36.52 2 2 1 16 239.77 6 ↓
Hi High (pH 8-9.5) 3.22 5.66 -2.25 1 2 0 15 238.762 6 ↓

Analogs

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Popular Name: N-cyclopropyl-N-ethyl-N'-(3-fluorophenyl)ethane-1,2-diamine N-cyclopropyl-N-ethyl-N'-(3-fluo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 7.53 -37.56 2 2 1 16 223.315 6 ↓
Hi High (pH 8-9.5) 2.71 5.21 -2.89 1 2 0 15 222.307 6 ↓

Analogs

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Popular Name: N'-(3-bromophenyl)-N-cyclopropyl-N-ethyl-ethane-1,2-diamine N'-(3-bromophenyl)-N-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.35 8.09 -36.49 2 2 1 16 284.221 6 ↓
Hi High (pH 8-9.5) 3.35 5.77 -2.22 1 2 0 15 283.213 6 ↓

Analogs

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Popular Name: N-cyclopropyl-N-ethyl-N'-(o-tolyl)ethane-1,2-diamine N-cyclopropyl-N-ethyl-N'-(o-toly…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.97 8.25 -34.6 2 2 1 16 219.352 6 ↓
Hi High (pH 8-9.5) 2.97 5.94 -2.41 1 2 0 15 218.344 6 ↓

Analogs

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Popular Name: N'-(4-bromophenyl)-N-cyclopropyl-N-ethyl-ethane-1,2-diamine N'-(4-bromophenyl)-N-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.38 8.09 -36.83 2 2 1 16 284.221 6 ↓
Hi High (pH 8-9.5) 3.38 5.77 -2.31 1 2 0 15 283.213 6 ↓

Analogs

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Popular Name: N-cyclopropyl-N'-(4-fluorophenyl)-N-propyl-ethane-1,2-diamine N-cyclopropyl-N'-(4-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 8.27 -38.57 2 2 1 16 237.342 7 ↓
Hi High (pH 8-9.5) 3.23 5.97 -2.98 1 2 0 15 236.334 7 ↓

Analogs

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Popular Name: N'-(2-bromophenyl)-N-cyclopropyl-N-propyl-ethane-1,2-diamine N'-(2-bromophenyl)-N-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.83 8.92 -35.06 2 2 1 16 298.248 7 ↓
Hi High (pH 8-9.5) 3.83 6.62 -2.05 1 2 0 15 297.24 7 ↓

Analogs

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Popular Name: N'-(2-chlorophenyl)-N-cyclopropyl-N-propyl-ethane-1,2-diamine N'-(2-chlorophenyl)-N-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 8.79 -35.02 2 2 1 16 253.797 7 ↓
Hi High (pH 8-9.5) 3.70 6.49 -2.06 1 2 0 15 252.789 7 ↓

Analogs

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Popular Name: N-cyclopropyl-N'-(m-tolyl)-N-propyl-ethane-1,2-diamine N-cyclopropyl-N'-(m-tolyl)-N-pro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.49 8.86 -34.89 2 2 1 16 233.379 7 ↓
Hi High (pH 8-9.5) 3.49 6.56 -2.35 1 2 0 15 232.371 7 ↓

Analogs

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Popular Name: N-cyclopropyl-N-propyl-N'-(p-tolyl)ethane-1,2-diamine N-cyclopropyl-N-propyl-N'-(p-tol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.52 8.87 -34.78 2 2 1 16 233.379 7 ↓
Hi High (pH 8-9.5) 3.52 6.57 -2.26 1 2 0 15 232.371 7 ↓

Analogs

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Popular Name: N'-(4-chlorophenyl)-N-cyclopropyl-N-propyl-ethane-1,2-diamine N'-(4-chlorophenyl)-N-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.75 8.72 -37.44 2 2 1 16 253.797 7 ↓
Hi High (pH 8-9.5) 3.75 6.42 -2.27 1 2 0 15 252.789 7 ↓

Analogs

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Popular Name: N-cyclopropyl-N'-(2-fluorophenyl)-N-propyl-ethane-1,2-diamine N-cyclopropyl-N'-(2-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.19 8.29 -35.81 2 2 1 16 237.342 7 ↓
Hi High (pH 8-9.5) 3.19 5.99 -2.76 1 2 0 15 236.334 7 ↓

Analogs

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Popular Name: N'-(3-chlorophenyl)-N-cyclopropyl-N-propyl-ethane-1,2-diamine N'-(3-chlorophenyl)-N-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 8.72 -37.22 2 2 1 16 253.797 7 ↓
Hi High (pH 8-9.5) 3.72 6.42 -2.18 1 2 0 15 252.789 7 ↓

Analogs

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Popular Name: N-cyclopropyl-N'-(3-fluorophenyl)-N-propyl-ethane-1,2-diamine N-cyclopropyl-N'-(3-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 8.27 -38.3 2 2 1 16 237.342 7 ↓
Hi High (pH 8-9.5) 3.21 5.97 -2.73 1 2 0 15 236.334 7 ↓

Analogs

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Popular Name: N'-(3-bromophenyl)-N-cyclopropyl-N-propyl-ethane-1,2-diamine N'-(3-bromophenyl)-N-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.85 8.82 -37.18 2 2 1 16 298.248 7 ↓
Hi High (pH 8-9.5) 3.85 6.52 -2.11 1 2 0 15 297.24 7 ↓

Analogs

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Popular Name: N-cyclopropyl-N'-(o-tolyl)-N-propyl-ethane-1,2-diamine N-cyclopropyl-N'-(o-tolyl)-N-pro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 9 -35.27 2 2 1 16 233.379 7 ↓
Hi High (pH 8-9.5) 3.47 6.7 -2.36 1 2 0 15 232.371 7 ↓

Analogs

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Popular Name: N'-(4-bromophenyl)-N-cyclopropyl-N-propyl-ethane-1,2-diamine N'-(4-bromophenyl)-N-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.88 8.82 -37.55 2 2 1 16 298.248 7 ↓
Hi High (pH 8-9.5) 3.88 6.52 -2.22 1 2 0 15 297.24 7 ↓

Analogs

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Popular Name: N'-cyclopropyl-N-(4-fluorophenyl)ethane-1,2-diamine N'-cyclopropyl-N-(4-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.11 4.98 -43.36 3 2 1 29 195.261 5 ↓

Analogs

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Popular Name: N-(2-bromophenyl)-N'-cyclopropyl-ethane-1,2-diamine N-(2-bromophenyl)-N'-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 5.63 -39.95 3 2 1 29 256.167 5 ↓

Analogs

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Popular Name: N-(2-chlorophenyl)-N'-cyclopropyl-ethane-1,2-diamine N-(2-chlorophenyl)-N'-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.58 5.5 -39.83 3 2 1 29 211.716 5 ↓

Analogs

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Popular Name: N'-cyclopropyl-N-(m-tolyl)ethane-1,2-diamine N'-cyclopropyl-N-(m-tolyl)ethane…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.37 5.58 -39.5 3 2 1 29 191.298 5 ↓

Analogs

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Popular Name: N'-cyclopropyl-N-(p-tolyl)ethane-1,2-diamine N'-cyclopropyl-N-(p-tolyl)ethane…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 5.59 -39.44 3 2 1 29 191.298 5 ↓

Analogs

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Popular Name: N-(4-chlorophenyl)-N'-cyclopropyl-ethane-1,2-diamine N-(4-chlorophenyl)-N'-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 5.43 -42.19 3 2 1 29 211.716 5 ↓

Analogs

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Popular Name: N'-cyclopropyl-N-(2-fluorophenyl)ethane-1,2-diamine N'-cyclopropyl-N-(2-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.06 5 -40.68 3 2 1 29 195.261 5 ↓

Analogs

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Popular Name: N-(3-chlorophenyl)-N'-cyclopropyl-ethane-1,2-diamine N-(3-chlorophenyl)-N'-cyclopropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.60 5.42 -40.39 3 2 1 29 211.716 5 ↓

Analogs

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Popular Name: N'-cyclopropyl-N-(3-fluorophenyl)ethane-1,2-diamine N'-cyclopropyl-N-(3-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.08 4.98 -41.24 3 2 1 29 195.261 5 ↓

Analogs

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Popular Name: N-(3-bromophenyl)-N'-cyclopropyl-ethane-1,2-diamine N-(3-bromophenyl)-N'-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 5.53 -40.3 3 2 1 29 256.167 5 ↓

Analogs

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Popular Name: N'-cyclopropyl-N-(o-tolyl)ethane-1,2-diamine N'-cyclopropyl-N-(o-tolyl)ethane…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 5.71 -39.92 3 2 1 29 191.298 5 ↓

Analogs

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Popular Name: N-(4-bromophenyl)-N'-cyclopropyl-ethane-1,2-diamine N-(4-bromophenyl)-N'-cyclopropyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.75 5.54 -42.32 3 2 1 29 256.167 5 ↓

Analogs

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Popular Name: N'-cyclopropyl-N-(4-fluorophenyl)-N'-(2,2,2-trifluoroethyl)ethane-1,2-diamine N'-cyclopropyl-N-(4-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 5.86 -4.87 1 2 0 15 276.277 7 ↓
Lo Low (pH 4.5-6) 3.28 7.86 -42.88 2 2 1 16 277.285 7 ↓

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