ZINC 12

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ZINC Item

Suppliers, Protomers, & Similar Substances

44243127

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-4-[(5-bromo-3-pyridyl)sulfonyl]morpholine-2-carboxylic (2S)-4-[(5-bromo-3-pyridyl)sulfo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.21	2.22	-47.8	0	7	-1	100	350.17	3	↓ MOL2 SDF SMILES Flexibase

44243129

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-4-[(5-bromo-3-pyridyl)sulfonyl]morpholine-2-carboxylic (2R)-4-[(5-bromo-3-pyridyl)sulfo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.21	2.29	-48.37	0	7	-1	100	350.17	3	↓ MOL2 SDF SMILES Flexibase

50656174

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-methyl-5-[(3R)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine N-methyl-5-[(3R)-3-methylmorphol…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	0.5	-9.83	1	6	0	72	271.342	3	↓ MOL2 SDF SMILES Flexibase

50656176

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-methyl-5-[(3S)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine N-methyl-5-[(3S)-3-methylmorphol…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	0.51	-10.01	1	6	0	72	271.342	3	↓ MOL2 SDF SMILES Flexibase

50656179

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-ethyl-5-[(3S)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine N-ethyl-5-[(3S)-3-methylmorpholi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.93	1.32	-9.31	1	6	0	72	285.369	4	↓ MOL2 SDF SMILES Flexibase

50656181

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-ethyl-5-[(3R)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine N-ethyl-5-[(3R)-3-methylmorpholi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.93	1.34	-9.46	1	6	0	72	285.369	4	↓ MOL2 SDF SMILES Flexibase

50656183

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[(3S)-3-methylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 5-[(3S)-3-methylmorpholin-4-yl]s…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.43	2.08	-9	1	6	0	72	299.396	5	↓ MOL2 SDF SMILES Flexibase

50656186

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[(3R)-3-methylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 5-[(3R)-3-methylmorpholin-4-yl]s…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.43	2.1	-9.16	1	6	0	72	299.396	5	↓ MOL2 SDF SMILES Flexibase

50656222

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-methyl-3-[(3R)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine N-methyl-3-[(3R)-3-methylmorphol…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.34	1.25	-9.93	1	6	0	72	271.342	3	↓ MOL2 SDF SMILES Flexibase

50656225

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-methyl-3-[(3S)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine N-methyl-3-[(3S)-3-methylmorphol…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.34	1.32	-9.98	1	6	0	72	271.342	3	↓ MOL2 SDF SMILES Flexibase

50656227

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-ethyl-3-[(3S)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine N-ethyl-3-[(3S)-3-methylmorpholi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.71	2.13	-9.7	1	6	0	72	285.369	4	↓ MOL2 SDF SMILES Flexibase

50656230

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-ethyl-3-[(3R)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine N-ethyl-3-[(3R)-3-methylmorpholi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.71	2.08	-9.76	1	6	0	72	285.369	4	↓ MOL2 SDF SMILES Flexibase

50656231

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(3S)-3-methylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 3-[(3S)-3-methylmorpholin-4-yl]s…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.22	2.9	-9.55	1	6	0	72	299.396	5	↓ MOL2 SDF SMILES Flexibase

50656234

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(3R)-3-methylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 3-[(3R)-3-methylmorpholin-4-yl]s…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.22	2.85	-9.52	1	6	0	72	299.396	5	↓ MOL2 SDF SMILES Flexibase

50656272

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-methyl-3-[(3R)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine 5-bromo-N-methyl-3-[(3R)-3-methy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.29	1.85	-8.14	1	6	0	72	350.238	3	↓ MOL2 SDF SMILES Flexibase

50656274

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-methyl-3-[(3S)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine 5-bromo-N-methyl-3-[(3S)-3-methy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.29	1.91	-8.24	1	6	0	72	350.238	3	↓ MOL2 SDF SMILES Flexibase

50656276

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-ethyl-3-[(3S)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine 5-bromo-N-ethyl-3-[(3S)-3-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.67	2.73	-7.89	1	6	0	72	364.265	4	↓ MOL2 SDF SMILES Flexibase

50656278

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-ethyl-3-[(3R)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine 5-bromo-N-ethyl-3-[(3R)-3-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.67	2.67	-7.9	1	6	0	72	364.265	4	↓ MOL2 SDF SMILES Flexibase

50656280

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-3-[(3S)-3-methylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 5-bromo-3-[(3S)-3-methylmorpholi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.17	3.49	-7.69	1	6	0	72	378.292	5	↓ MOL2 SDF SMILES Flexibase

50656282

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-3-[(3R)-3-methylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 5-bromo-3-[(3R)-3-methylmorpholi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.17	3.44	-7.63	1	6	0	72	378.292	5	↓ MOL2 SDF SMILES Flexibase

50656285

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[(3R)-3-methylmorpholin-4-yl]sulfonylpyridin-2-amine 5-[(3R)-3-methylmorpholin-4-yl]s…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.18	-0.41	-9.91	2	6	0	86	257.315	2	↓ MOL2 SDF SMILES Flexibase

50656286

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[(3S)-3-methylmorpholin-4-yl]sulfonylpyridin-2-amine 5-[(3S)-3-methylmorpholin-4-yl]s…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.18	-0.4	-10.05	2	6	0	86	257.315	2	↓ MOL2 SDF SMILES Flexibase

50656298

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(3R)-3-methylmorpholin-4-yl]sulfonylpyridin-2-amine 3-[(3R)-3-methylmorpholin-4-yl]s…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.04	0.05	-9.62	2	6	0	86	257.315	2	↓ MOL2 SDF SMILES Flexibase

50656300

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(3S)-3-methylmorpholin-4-yl]sulfonylpyridin-2-amine 3-[(3S)-3-methylmorpholin-4-yl]s…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.04	-0.02	-9.53	2	6	0	86	257.315	2	↓ MOL2 SDF SMILES Flexibase

50656323

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-3-[(3R)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine 5-bromo-3-[(3R)-3-methylmorpholi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.92	0.64	-7.95	2	6	0	86	336.211	2	↓ MOL2 SDF SMILES Flexibase

50656325

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-3-[(3S)-3-methylmorpholin-4-yl]sulfonyl-pyridin-2-amine 5-bromo-3-[(3S)-3-methylmorpholi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.92	0.58	-7.95	2	6	0	86	336.211	2	↓ MOL2 SDF SMILES Flexibase

50656583

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[(2R,5R)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-methyl-pyridin-2-amine 5-[(2R,5R)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.92	1.34	-10.14	1	6	0	72	285.369	3	↓ MOL2 SDF SMILES Flexibase

50656584

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[(2S,5R)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-methyl-pyridin-2-amine 5-[(2S,5R)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.92	1.24	-9.65	1	6	0	72	285.369	3	↓ MOL2 SDF SMILES Flexibase

50656587

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[(2S,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-ethyl-pyridin-2-amine 5-[(2S,5S)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.29	2.13	-9.63	1	6	0	72	299.396	4	↓ MOL2 SDF SMILES Flexibase

50656589

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[(2R,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-ethyl-pyridin-2-amine 5-[(2R,5S)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.29	2.06	-9.1	1	6	0	72	299.396	4	↓ MOL2 SDF SMILES Flexibase

50656591

Analogs

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Popular Name: 5-[(2S,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 5-[(2S,5S)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.80	2.89	-9.33	1	6	0	72	313.423	5	↓ MOL2 SDF SMILES Flexibase

50656593

Analogs

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Popular Name: 5-[(2R,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 5-[(2R,5S)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.80	2.83	-8.87	1	6	0	72	313.423	5	↓ MOL2 SDF SMILES Flexibase

50656618

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(2R,5R)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-methyl-pyridin-2-amine 3-[(2R,5R)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.70	2.15	-9.95	1	6	0	72	285.369	3	↓ MOL2 SDF SMILES Flexibase

50656621

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(2S,5R)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-methyl-pyridin-2-amine 3-[(2S,5R)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.70	2.02	-9.71	1	6	0	72	285.369	3	↓ MOL2 SDF SMILES Flexibase

50656622

Analogs

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Popular Name: 3-[(2S,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-ethyl-pyridin-2-amine 3-[(2S,5S)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.08	2.93	-9.84	1	6	0	72	299.396	4	↓ MOL2 SDF SMILES Flexibase

50656625

Analogs

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Popular Name: 3-[(2R,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-ethyl-pyridin-2-amine 3-[(2R,5S)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.08	2.73	-9.63	1	6	0	72	299.396	4	↓ MOL2 SDF SMILES Flexibase

50656628

Analogs

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Popular Name: 3-[(2S,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 3-[(2S,5S)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.58	3.7	-9.55	1	6	0	72	313.423	5	↓ MOL2 SDF SMILES Flexibase

50656629

Analogs

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Popular Name: 3-[(2R,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-propyl-pyridin-2-amine 3-[(2R,5S)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.58	3.49	-9.36	1	6	0	72	313.423	5	↓ MOL2 SDF SMILES Flexibase

50656663

Analogs

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Popular Name: 5-bromo-3-[(2R,5R)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-methyl-pyridin-2-amine 5-bromo-3-[(2R,5R)-2,5-dimethylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.66	2.74	-8.24	1	6	0	72	364.265	3	↓ MOL2 SDF SMILES Flexibase

50656666

Analogs

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Popular Name: 5-bromo-3-[(2S,5R)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-methyl-pyridin-2-amine 5-bromo-3-[(2S,5R)-2,5-dimethylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.66	2.62	-7.94	1	6	0	72	364.265	3	↓ MOL2 SDF SMILES Flexibase

50656669

Analogs

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Popular Name: 5-bromo-3-[(2S,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-ethyl-pyridin-2-amine 5-bromo-3-[(2S,5S)-2,5-dimethylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.03	3.53	-7.96	1	6	0	72	378.292	4	↓ MOL2 SDF SMILES Flexibase

50656671

Analogs

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Popular Name: 5-bromo-3-[(2R,5S)-2,5-dimethylmorpholin-4-yl]sulfonyl-N-ethyl-pyridin-2-amine 5-bromo-3-[(2R,5S)-2,5-dimethylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.03	3.32	-7.67	1	6	0	72	378.292	4	↓ MOL2 SDF SMILES Flexibase

50656674

Analogs

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Popular Name: 5-[(2R,5R)-2,5-dimethylmorpholin-4-yl]sulfonylpyridin-2-amine 5-[(2R,5R)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.54	0.43	-10.16	2	6	0	86	271.342	2	↓ MOL2 SDF SMILES Flexibase

50656677

Analogs

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Popular Name: 5-[(2S,5R)-2,5-dimethylmorpholin-4-yl]sulfonylpyridin-2-amine 5-[(2S,5R)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.54	0.33	-9.73	2	6	0	86	271.342	2	↓ MOL2 SDF SMILES Flexibase

50656683

Analogs

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Popular Name: 3-[(2R,5R)-2,5-dimethylmorpholin-4-yl]sulfonylpyridin-2-amine 3-[(2R,5R)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.32	0.9	-9.53	2	6	0	86	271.342	2	↓ MOL2 SDF SMILES Flexibase

50656685

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(2S,5R)-2,5-dimethylmorpholin-4-yl]sulfonylpyridin-2-amine 3-[(2S,5R)-2,5-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.32	0.81	-9.33	2	6	0	86	271.342	2	↓ MOL2 SDF SMILES Flexibase

50656701

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-3-[(2R,5R)-2,5-dimethylmorpholin-4-yl]sulfonyl-pyridin-2-amine 5-bromo-3-[(2R,5R)-2,5-dimethylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.28	1.49	-7.9	2	6	0	86	350.238	2	↓ MOL2 SDF SMILES Flexibase

50656704

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-3-[(2S,5R)-2,5-dimethylmorpholin-4-yl]sulfonyl-pyridin-2-amine 5-bromo-3-[(2S,5R)-2,5-dimethylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.28	1.42	-7.68	2	6	0	86	350.238	2	↓ MOL2 SDF SMILES Flexibase

50657303

Analogs

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Popular Name: 5-[(2R)-2-ethylmorpholin-4-yl]sulfonyl-N-methyl-pyridin-2-amine 5-[(2R)-2-ethylmorpholin-4-yl]su…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.09	1.49	-10.2	1	6	0	72	285.369	4	↓ MOL2 SDF SMILES Flexibase

50657304

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[(2S)-2-ethylmorpholin-4-yl]sulfonyl-N-methyl-pyridin-2-amine 5-[(2S)-2-ethylmorpholin-4-yl]su…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.09	1.52	-10.16	1	6	0	72	285.369	4	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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