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    • Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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    Analogs

    6037202
    6037202

    Draw Identity 99% 90% 80% 70%

    Popular Name: INN) INN)

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.83 -0.81 -45.8 0 3 -1 53 311.18 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(2,5-dimethoxyphenyl)thiazol-2-yl]carbamoylmethyl [4-(2,5-dimethoxyphenyl)thiazol-…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.88 1.23 -14.13 1 7 0 86 364.423 9 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[4-(4-butoxyphenyl)thiazol-2-yl]butanamide N-[4-(4-butoxyphenyl)thiazol-2-y…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 4.78 -0.15 -10.19 1 4 0 51 318.442 8 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%


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    Popular Name:

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.42 -1.82 -46.36 1 5 -1 82 354.205 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[4-(4-chlorophenyl)-5-methyl-thiazol-2-yl]-4-ethoxy-butanamide N-[4-(4-chlorophenyl)-5-methyl-t…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.64 8.22 -11.83 1 4 0 51 338.86 7 ↓

    Analogs

    2609524
    2609524
    5697233
    5697233

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[4-(4-bromophenyl)-5-methyl-thiazol-2-yl]-4-methoxy-butanamide N-[4-(4-bromophenyl)-5-methyl-th…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.40 7.36 -11.67 1 4 0 51 369.284 6 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 4-(2,4-dichlorophenyl)-1,3-thiazole-2-thiol 4-(2,4-dichlorophenyl)-1,3-thiaz…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 4.34 7.38 -40.72 0 1 -1 13 261.178 1 ↓

    Analogs

    17005272
    17005272

    Draw Identity 99% 90% 80% 70%

    Popular Name: 5-(2-bromoethyl)-4-(4-fluorophenyl)thiazol-2-amine 5-(2-bromoethyl)-4-(4-fluorophen…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.47 6.64 -5.81 2 2 0 39 301.184 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[4-(3,4-difluorophenyl)thiazol-2-yl]-2-[methyl(methylsulfonyl)amino]acetamide N-[4-(3,4-difluorophenyl)thiazol…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.87 3.93 -23.99 1 6 0 79 361.395 5 ↓
    Hi High (pH 8-9.5) 1.69 2.39 -53.31 0 6 -1 86 360.387 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-[3-methoxypropyl(methyl)amino]-4-phenyl-thiazole-5-carbaldehyde 2-[3-methoxypropyl(methyl)amino]…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.05 7.4 -11.22 0 4 0 42 290.388 7 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-[3-methoxypropyl(methyl)amino]-4-phenyl-thiazole-5-carboxylic 2-[3-methoxypropyl(methyl)amino]…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.83 6.77 -61.05 0 5 -1 65 305.379 7 ↓
    Lo Low (pH 4.5-6) 2.83 7.18 -45.62 1 5 0 67 306.387 7 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(3-methoxypropyl)-N-methyl-5-(methylaminomethyl)-4-phenyl-thiazol-2-amine N-(3-methoxypropyl)-N-methyl-5-(…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.82 7.74 -39.27 2 4 1 42 306.455 8 ↓
    Hi High (pH 8-9.5) 2.82 7.09 -8.4 1 4 0 37 305.447 8 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 5-(aminomethyl)-N-(3-methoxypropyl)-N-methyl-4-phenyl-thiazol-2-amine 5-(aminomethyl)-N-(3-methoxyprop…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.44 5.88 -44.52 3 4 1 53 292.428 7 ↓
    Mid Mid (pH 6-8) 2.44 5.48 -8.66 2 4 0 51 291.42 7 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [2-[3-methoxypropyl(methyl)amino]-4-phenyl-thiazol-5-yl]methanol [2-[3-methoxypropyl(methyl)amino…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.60 5.42 -10.85 1 4 0 46 292.404 7 ↓
    Lo Low (pH 4.5-6) 2.60 5.55 -26.87 2 4 1 47 293.412 7 ↓

    Analogs

    42407119
    42407119
    34363047
    34363047

    Draw Identity 99% 90% 80% 70%

    Popular Name: Ethyl 4-phenylthiazole-2-carboxylate Ethyl 4-phenylthiazole-2-carboxy…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.48 6.86 -11.14 0 3 0 39 233.292 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: Ethyl4-(4-Fluorophenyl)-2-thiazolecarboxylate Ethyl4-(4-Fluorophenyl)-2-thiazo…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.65 6.93 -11.11 0 3 0 39 251.282 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: Ethyl 4-(3-methoxyphenyl)thiazole-2-carboxylate Ethyl 4-(3-methoxyphenyl)thiazol…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.51 6.16 -14.67 0 4 0 48 263.318 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: ethyl 4-(4-nitrophenyl)-1,3-thiazole-2-carboxylate ethyl 4-(4-nitrophenyl)-1,3-thia…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.44 7.57 -14.28 0 6 0 85 278.289 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: (2S)-N-[4-(2,5-dichlorophenyl)thiazol-2-yl]-2-methoxy-propanamide (2S)-N-[4-(2,5-dichlorophenyl)th…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.48 7.76 -10.84 1 4 0 51 331.224 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: (2R)-N-[4-(2,5-dichlorophenyl)thiazol-2-yl]-2-methoxy-propanamide (2R)-N-[4-(2,5-dichlorophenyl)th…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.48 7.75 -10.8 1 4 0 51 331.224 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-amino-5-(2-methylthiazol-4-yl)phenol 2-amino-5-(2-methylthiazol-4-yl)…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.45 1.14 -8.86 3 3 0 59 206.27 1 ↓
    Lo Low (pH 4.5-6) 1.45 1.5 -28.95 4 3 1 60 207.278 1 ↓

    Analogs

    4461610
    4461610
    4505762
    4505762

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-[bis(2-methoxyethyl)amino]-N-[4-(p-tolyl)thiazol-2-yl]acetamide 2-[bis(2-methoxyethyl)amino]-N-[…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.66 7.39 -46.47 2 6 1 65 364.491 10 ↓
    Mid Mid (pH 6-8) 2.66 5.23 -12.08 1 6 0 64 363.483 10 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-[bis(2-methoxyethyl)amino]-N-[4-(4-fluorophenyl)thiazol-2-yl]acetamide 2-[bis(2-methoxyethyl)amino]-N-[…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.37 6.78 -47.52 2 6 1 65 368.454 10 ↓
    Mid Mid (pH 6-8) 2.37 5.56 -10.86 1 6 0 64 367.446 10 ↓

    Analogs

    39972113
    39972113

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-[ethyl-[2-(isopropylamino)-2-oxo-ethyl]amino]-N-[4-(p-tolyl)thiazol-2-yl]acetamide 2-[ethyl-[2-(isopropylamino)-2-o…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.35 8.43 -47.18 3 6 1 76 375.518 8 ↓
    Mid Mid (pH 6-8) 3.35 6.41 -15.74 2 6 0 74 374.51 8 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-[ethyl-[2-(isopropylamino)-2-oxo-ethyl]amino]-N-[4-(4-fluorophenyl)thiazol-2-yl]acetamide 2-[ethyl-[2-(isopropylamino)-2-o…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.06 7.82 -47.98 3 6 1 76 379.481 8 ↓
    Mid Mid (pH 6-8) 3.06 5.79 -15.45 2 6 0 74 378.473 8 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-[[2-(tert-butylamino)-2-oxo-ethyl]-ethyl-amino]-N-[4-(4-fluorophenyl)thiazol-2-yl]acetamide 2-[[2-(tert-butylamino)-2-oxo-et…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.57 8.31 -47.75 3 6 1 76 393.508 8 ↓
    Mid Mid (pH 6-8) 3.57 6.28 -14.54 2 6 0 74 392.5 8 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 4-(2,5-difluorophenyl)thiazole-5-carboxylic 4-(2,5-difluorophenyl)thiazole-5…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.61 5.9 -49.18 0 3 -1 53 240.21 2 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-[4-(4-isopropylphenyl)thiazol-2-yl]ethanone 1-[4-(4-isopropylphenyl)thiazol-…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.68 7.66 -12.75 0 2 0 30 245.347 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-[4-(4-propylphenyl)thiazol-2-yl]ethanone 1-[4-(4-propylphenyl)thiazol-2-y…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.48 7.99 -13.01 0 2 0 30 245.347 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-[4-(2,4,6-trimethylphenyl)thiazol-2-yl]ethanone 1-[4-(2,4,6-trimethylphenyl)thia…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.37 7.74 -12.08 0 2 0 30 245.347 2 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-[4-(2,4,5-trimethylphenyl)thiazol-2-yl]ethanone 1-[4-(2,4,5-trimethylphenyl)thia…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.37 7.7 -11.84 0 2 0 30 245.347 2 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-[4-(2-methoxy-5-methyl-phenyl)thiazol-2-yl]ethanone 1-[4-(2-methoxy-5-methyl-phenyl)…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.60 6.17 -14.82 0 3 0 39 247.319 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-[4-(4-ethoxyphenyl)thiazol-2-yl]ethanone 1-[4-(4-ethoxyphenyl)thiazol-2-y…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.60 6.02 -13.76 0 3 0 39 247.319 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 4-(4-propoxyphenyl)thiazol-5-amine 4-(4-propoxyphenyl)thiazol-5-amine

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.08 4.56 -7.02 2 3 0 48 234.324 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-methyl-4-(4-propoxyphenyl)thiazol-5-amine 2-methyl-4-(4-propoxyphenyl)thia…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.80 5.3 -7.16 2 3 0 48 248.351 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-ethyl-4-(4-propoxyphenyl)thiazol-5-amine 2-ethyl-4-(4-propoxyphenyl)thiaz…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.37 6.06 -6.86 2 3 0 48 262.378 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 4-(4-propoxyphenyl)-2-propyl-thiazol-5-amine 4-(4-propoxyphenyl)-2-propyl-thi…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.87 6.83 -6.59 2 3 0 48 276.405 6 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-isopropyl-4-(4-propoxyphenyl)thiazol-5-amine 2-isopropyl-4-(4-propoxyphenyl)t…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.85 6.66 -6.69 2 3 0 48 276.405 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 4-(3-propoxyphenyl)thiazol-5-amine 4-(3-propoxyphenyl)thiazol-5-amine

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.06 4.55 -9.03 2 3 0 48 234.324 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-methyl-4-(3-propoxyphenyl)thiazol-5-amine 2-methyl-4-(3-propoxyphenyl)thia…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.77 5.29 -9.21 2 3 0 48 248.351 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-ethyl-4-(3-propoxyphenyl)thiazol-5-amine 2-ethyl-4-(3-propoxyphenyl)thiaz…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.35 6.05 -8.97 2 3 0 48 262.378 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 4-(3-propoxyphenyl)-2-propyl-thiazol-5-amine 4-(3-propoxyphenyl)-2-propyl-thi…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.85 6.82 -8.71 2 3 0 48 276.405 6 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-isopropyl-4-(3-propoxyphenyl)thiazol-5-amine 2-isopropyl-4-(3-propoxyphenyl)t…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.83 6.64 -8.85 2 3 0 48 276.405 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(3-ethyl-4-methoxy-phenyl)thiazol-2-yl]hydrazine [4-(3-ethyl-4-methoxy-phenyl)thi…

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    Activity (Go SEA)

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.81 5.03 -7.96 3 4 0 60 249.339 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(5-ethyl-2-methoxy-phenyl)thiazol-2-yl]hydrazine [4-(5-ethyl-2-methoxy-phenyl)thi…

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    Activity (Go SEA)

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.81 5.44 -8.62 3 4 0 60 249.339 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(2-methoxy-3,5-dimethyl-phenyl)thiazol-2-yl]hydrazine [4-(2-methoxy-3,5-dimethyl-pheny…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.72 5.7 -8.24 3 4 0 60 249.339 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 4-[4-(2-methoxyethoxy)phenyl]thiazol-2-amine 4-[4-(2-methoxyethoxy)phenyl]thi…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.10 4.04 -9.1 2 4 0 57 250.323 5 ↓
    Lo Low (pH 4.5-6) 2.10 4.39 -32.56 3 4 1 59 251.331 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-[4-(3-fluoro-4-methoxy-phenyl)thiazol-2-yl]ethanone 1-[4-(3-fluoro-4-methoxy-phenyl)…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.32 5.14 -18.45 0 3 0 39 251.282 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(4-ethoxy-3-fluoro-phenyl)thiazol-2-yl]hydrazine [4-(4-ethoxy-3-fluoro-phenyl)thi…

    Find On: PubMed — Wikipedia — Google

    Activity (Go SEA)

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.43 4.54 -8.17 3 4 0 60 253.302 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[4-(4-tert-butylphenyl)thiazol-2-yl]-2-ethylsulfonyl-acetamide N-[4-(4-tert-butylphenyl)thiazol…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.33 6.55 -24.81 1 5 0 76 366.508 6 ↓

    Parameters Provided:

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    Structural Results Found: (before additional filtering)

    SQL Query Was

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    Permalink

    //zinc12.docking.org/results/combination?ring.id=80&filter.purchasability=annotated

    Embed Link to Results

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