| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 23rd, 2008 | 27 | No |
Popular Name: N-[(5-acetamido-2-methoxy-phenyl)carbamoyl]-2-chloro-4,5-difluoro-benzamide N-[(5-acetamido-2-methoxy-phenyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.54 | 5.42 | -19.27 | 3 | 7 | 0 | 97 | 397.765 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL-1-E | Liver Glycogen Phosphorylase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 60 | 0.37 | Binding ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 600 | 0.32 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 60 | 0.37 | Binding ≤ 1μM |
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 60 | 0.37 | Binding ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 600 | 0.32 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Glycogen breakdown (glycogenolysis) |
