UCSF

ZINC01532522

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 6th, 2004 10 Yes

Popular Name: L-LYSINE L-LYSINE

Find On: PubMed — Wikipedia — Google

CAS Numbers: 10098-89-2 , 20166-34-1 , 22834-80-6 , 25104-18-1 , 27348-32-9 , 286437-16-9 , 39665-12-8 , 52315-92-1 , 5408-52-6 , 56-87-1 , 57282-49-2 , 6150-68-1 , 617-68-5 , 62952-06-1 , 657-26-1 , 657-27-2 , 6899-06-5 , 70-53-1 , 70-54-2 , 71555-10-7 , 7274-88-6 , 885701-25-7 , [52315-92-1] , [5408-52-6] , [6150-68-1] , [657-27-2] , [70-53-1] , [70-54-2]

Other Names:

"D-Lysine hydrochloride, 99%"

"DL-Lysine monohydrochloride, 99%"

(+)-S-Lysine; (S)-2,6-diamino-Hexanoate; (S)-2,6-diamino-Hexanoic acid; (S)-2,6-Diaminohexanoate; (S)-2,6-Diaminohexanoic acid; (S)-a,e-Diaminocaproate; (S)-a,e-Diaminocaproic acid; (S)-Lysine; 2,6-Diaminohexanoate; 2,6-Diaminohexanoic acid; 6-amino-Aminu

(+)-S-Lysine; (S)-2,6-Diaminohexanoate; (S)-2,6-Diaminohexanoic acid; (S)-2,6-diamino-Hexanoate; (S)-2,6-diamino-Hexanoic acid; (S)-Lysine; (S)-a,e-Diaminocaproate; (S)-a,e-Diaminocaproic acid; 2,6-Diaminohexanoate; 2,6-Diaminohexanoic acid; 6-Amino-Aminu

(+)-S-Lysine;(S)-2,6-diamino-Hexanoate;(S)-2,6-diamino-Hexanoic acid;(S)-2,6-Diaminohexanoate;(S)-2,6-Diaminohexanoic acid;(S)-a,e-Diaminocaproate;(S)-a,e-Diaminocaproic acid;(S)-Lysine;2,6-Diaminohexanoate;2,6-Diaminohexanoic acid;6-Amino-Aminutrin;6-Ami

(+)-S-Lysine;(S)-2,6-Diaminohexanoate;(S)-2,6-Diaminohexanoic acid;(S)-2,6-diamino-Hexanoate;(S)-2,6-diamino-Hexanoic acid;(S)-Lysine;(S)-a,e-Diaminocaproate;(S)-a,e-Diaminocaproic acid;2,6-Diaminohexanoate;2,6-Diaminohexanoic acid;6-Amino-Aminutrin;6-Ami

(+/-)-2,6-Diaminohexanoic acid monohydrate

(+/-)-2,6-Diaminohexanoic acid monohydrochloride

(2S)-2,6-diaminohexanoic acid

(R)-2,6-Diaminohexanoic acid monohydrochloride

(S)-(+)-Lysine

(S)-2,6-DiaminocaproicAcid

(S)-2,6-diaminohexanoic acid

(S)-2,6-Diaminohexanoic acid compound with (S)-2-aminopentanedioic acid (1:1)

(S)-2,6-Diaminohexanoic acid compound with (S)-2-aminosuccinic acid (1:1)

(S)-2,6-Diaminohexanoic acid dihydrochloride

(S)-2,6-Diaminohexanoic acid hydrochloride

(S)-2,6-Diaminohexanoic acid monohydrate

(S)-2,6-Diaminohexanoic acid monohydrochloride

(S)-2,6-Diaminohexanoic acid monohydrochloride; L-alpha,epsilondiaminocaproic acid monohydrochloride

(S)-2,6-diaminohexanoic acid; (S)-alpha,epsilon-diaminocaproic acid; (S)-lysine; K; L-2,6-Diaminocaproic acid; L-Lysin; Lys

(S)-α,ε-diaminocaproic acid

(S)-lysine

(S)-Lysine; (S)-alpha,epsilon-Diaminocaproic acid; 2,6-Diaminohexanoic acid; 2,6-Diaminohexanoic acid, (S)-; Aminutrin; Hexanoic acid, 2,6-diamino-, (S)-; L-LYSINE, MONOACETATE; L-Lysine; L-Norleucine, 6-amino-; LYS (IUPAC abbreviation); Lisina [Spanish]

2,6-diaminohexanoic acid

2,6-Diaminohexanoic acid hydrochloride

2,6-Diaminohexanoic acid; 56-87-1; C00047; L-Lysine; Lysine acid

2,6-diaminohexanoic acid; 56-87-1; L-lys; L-lysine; lys; lysine; lysine acid

3-bromo-N,N-dimethylbenzamide

56-87-1; D02304; L-Lysine; Lysine (USAN/INN)

CHEBI:43950; CHEBI:21351; CHEBI:13135; CHEBI:6264

D-Lysine

D-Lysine monohydrochloride

D-Lysine monohydrochloride, 98%

D06469; Lysine hydrochloride (JAN)

DL-Lysine

DL-Lysine Dihydrochloride

DL-lysine hydrochloride

DL-Lysine monohydrate

DL-Lysine monohydrate, 97%

DL-Lysine monohydrate, 98+%

DL-Lysine monohydrochloride

DL-Lysine monohydrochloride, 99%

DL-LYSINE-1,2-13C2 DIHYDROCHLORIDE

DL-LYSINE-1,2-13C2DIHYDROCHLORIDE

DL-lysinehydrochloride

DL-Lysinemonohydrate

dl-lysinemonohydrochloride

Enisyl

Epsilon-polylysine

H-D-Lys-OH.HCl

H-DL-Lys-OH

H-DL-Lys-OH.H_2O

H-Lys-OH H2O

H-Lys-OH.H2O

H-Lys-OH.HCl

INN)

K; LYS; Lysin; alpha,epsilon-diaminocaproic acid

L(+)-Lysine monohydrochloride, 99+%

L-(+)-Lysine

L-(+)-LysineDihydrochloride

L-lys

L-Lysine Acetate

L-Lysine dihydrochloride

L-Lysine dihydrochloride, 99%

L-Lysine HCl [657-27-2]; (H-Lys-OH . HCl)

L-LYSINE HCl; [657-27-2]

L-Lysine hydrate

L-Lysine hydrochloride

L-lysine l-aspartate

L-Lysine L-Glutamate

L-Lysine L-glutamate salt

L-lysine l-malate

L-lysine monohydrate

L-Lysine monohydrate, 98+%

L-Lysine monohydrochloride

L-Lysine monohydrochloride, 99+%

L-Lysine [56-87-1]

L-Lysine, 98%

L-Lysine, sulfite (2:1); LS-88487; Lysine sulfite

L-lysine, [4,5-3h(n)]-

L-Lysine,hydrochloride

L-Lysine-L-aspartate

L-LYSINE; [56-87-1]

l-lysinemonohydrate

LS-190705

LYS

lysine

Lysine (INN

Lysine (USAN

Lysine Acetate (USP)

lysine acid

Lysine HCl (JAN

LYSINEGLUTAMAT

MFCD00012920

MFCD00038974

MFCD00039069

MFCD00058085

MFCD00064432

MFCD00064433

MFCD00064563

MFCD00064564

MFCD00066389

MFCD00083397

MFCD00083648

MFCD00151035

MFCD00151036

N/A

NA

QA-6708

USAN

USAN)

USAN); Lysine Hydrochloride (JAN

USP)

USP); Lysine Acetate (USP)

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -3.18 -0.05 -85.42 6 4 1 95 147.198 5 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 1.05e+02 g/l DrugBank-experimental
UniProt Database Links 104K_THEAN; 13SB_FAGES; 194K_TRVSY; 1A_CCMV; 1A_OLV2I; 238R_IIV6; 255L_IIV6; 2ABB_RAT; 2B11_HUMAN; 2B13_HUMAN; 2B14_HUMAN; 2B17_HUMAN; 2B18_HUMAN; 2B19_HUMAN; 2B1A_HUMAN; 2B1B_HUMAN; 2B1C_HUMAN; 2B1D_HUMAN; 2B1E_HUMAN; 2B1F_HUMAN; 2B1G_HUMAN; 343L_IIV6; 3 ChEBI
MP 168 - 170 Enamine Building Blocks
MP 168...170 Enamine Building Blocks
Mp [°C] 202 Acros Organics
Melting_Point 202-206? Alfa-Aesar
Melting_Point 202-206° Alfa-Aesar
Melting_Point 210? dec. Alfa-Aesar
Melting_Point 210° dec. Alfa-Aesar
MP 215 °C (dec.)(lit.) Indofine
MP 215° (dec.) Oakwood Chemical
MP 218 - 220 Enamine Building Blocks
Mp [°C] 263 - 264 Acros Organics
MP 263 °C (dec.)(lit.) Indofine
Melting_Point 267? dec. Alfa-Aesar
Melting_Point 267° dec. Alfa-Aesar
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Purity 95% Fluorochem
Purity 95+% Matrix Scientific
Purity 97% Fluorochem
Purity 98% Fluorochem
Melting_Point ca 110? Alfa-Aesar
Melting_Point ca 110° Alfa-Aesar
Melting_Point ca 260? dec. Alfa-Aesar
Melting_Point ca 260° dec. Alfa-Aesar
Patent Database Links EP0857720; EP0892066; EP0898963; EP0922699; EP0933365; EP0971025; EP1106602; EP1106609; EP1113008; EP1123929; EP1132380; EP1151997; EP1179599; EP1219634; EP1256579; EP1265072; EP1323419; EP1323420; EP1338588; EP1364941; EP1369134; EP1422218; EP1502949; EP ChEBI
Patent Database Links EP0971027; EP1067116; EP1182261; EP1422218; EP1506970; EP1514554; EP1541585; EP1561454; EP1568283; EP1609462; EP1616963; EP1627884; EP1632228; EP1632233; EP1657249; EP1762232; EP1792627; EP1797860; EP1813600; EP1818049; EP1849466; EP1859810; EP1862172; EP ChEBI
SOLUBILITY H2O: 0.1 g/mL, clear, colorless Indofine
SOLUBILITY H2O: 100 mg/mL Indofine
Warnings IRRITANT Matrix Scientific
R phrase R36/37/38: Irritating to eyes, respiratory system and skin. Acros Organics
Reactome Database Links REACT_111140; REACT_111222; REACT_13736; REACT_14802; REACT_14813; REACT_14845; REACT_14848; REACT_14850; REACT_15291; REACT_15342; REACT_15537; REACT_15542; REACT_163642; REACT_169250; REACT_18362; REACT_19313; REACT_19377; REACT_22263; REACT_22436; REAC ChEBI
S phrase S24/25: Avoid contact with skin and eyes. Acros Organics
S phrase S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Acros Organics
Notes USP, Pyrogen free Apollo Scientific Bioactives
Hazard XI: Irritant Acros Organics

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description Species
Amino acid transport across the plasma membrane
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Antigen processing: Ubiquitination & Proteasome degradation
Biotin transport and metabolism
Class C/3 (Metabotropic glutamate/pheromone receptors)
Cross-presentation of soluble exogenous antigens (endosomes)
Cytosolic tRNA aminoacylation
Endosomal/Vacuolar pathway
ER-Phagosome pathway
G alpha (q) signalling events
Glutathione synthesis and recycling
Lysine catabolism
Mitochondrial tRNA aminoacylation
Na+/Cl- dependent neurotransmitter transporters
Proton/oligonucleotide cotransporters

Analogs ( Draw Identity 99% 90% 80% 70% )