In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 25th, 2005 | 25 | Yes |
Popular Name: Bezafibrate Bezafibrate
Find On: PubMed — Wikipedia — Google
CAS Numbers: 41859-67-0 , 63927-29-7 , [41859-67-0]
2-(4-{2-[(4-chlorobenzoyl)amino]ethyl}phenoxy)-2-methylpropanoic acid
2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid
2-[4-(2-[4-Chlorobenzamido]ethyl)- phenoxy]-2-methylpropanoic acid
2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid
2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid
2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid
41859-67-0; Bezafibrate (JP16/USAN/INN); Bezatol SR (TN); D01366
41859-67-0; Bezafibrate; Prestwick_724
a-[4-(4-chlorobenzoylaminoethyl)phenoxy]isobutyric acid
Azupharma Brand of Bezafibrate
Berlin Chemie Brand of Bezafibrate
Berlin-Chemie Brand of Bezafibrate
Betapharm Brand of Bezafibrate
Bezafibrat;Bezafibrato [inn-spanish];Bezafibratum [inn-latin]
Bezafibrate Berlin-Chemie Brand
Bezafibrate [USAN:BAN:INN:JAN]
bezafibrate; bezafibrato; bezafibratum
Boehringer Mannheim Brand of Bezafibrate
Cryopharma Brand of Bezafibrate
Propanoic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-
Propionic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.73 | 9.58 | -55.18 | 1 | 5 | -1 | 78 | 360.817 | 7 | ↓ |
Note Type | Comments | Provided By |
---|---|---|
ALOGPS_SOLUBILITY | 1.55e-03 g/l | DrugBank-approved |
MP | 184 | TCI |
Therapy | antihyperlipidemic | SMDC Iconix |
UniProt Database Links | DNM1L_RAT; FABPL_LEPPA; PANK1_HUMAN; TYSD1_MOUSE | ChEBI |
Patent Database Links | EP1258253; EP1522310; EP1553091; EP1559419; EP1655037; EP1714648; EP1723968; EP1746099; EP1782828; EP1785144; EP1832576; EP1884513; EP1889847; EP1911462; US2004073037; US2004092596; US2005009870; US2005014786; US2005080087; US2005209165; US2006154876; US2 | ChEBI |
Target | Others | Selleck Chemicals |
Target | PPAR | Selleck Chemicals |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
PPARG-2-E | Peroxisome Proliferator-activated Receptor Gamma (cluster #2 Of 2), Eukaryotic | Eukaryotes | 3000 | 0.31 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
PPARG_HUMAN | P37231 | Peroxisome Proliferator-activated Receptor Gamma, Human | 3000 | 0.31 | Functional ≤ 10μM |
Description | Species |
---|---|
Nuclear Receptor transcription pathway | |
PPARA activates gene expression | |
Transcriptional regulation of white adipocyte differentiation |
No pre-computed analogs available. Try a structural similarity search.