In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
December 21st, 2005 | 23 | No |
Popular Name: LS-125843 LS-125843
15-deoxy-Delta(12,14)-prostaglandin J2
15-Deoxy-PGJ2; 15-Deoxy-delta-12,14-PGJ2; 15-Deoxy-delta-12,14-prostaglandin J2
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.21 | 3.08 | -50.39 | 0 | 3 | -1 | 57 | 315.433 | 11 | ↓ |
Note Type | Comments | Provided By |
---|---|---|
Reactome Database Links | REACT_150262 | ChEBI |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
Z80418-3-O | RAW264.7 (Monocytic-macrophage Leukemia Cells) (cluster #3 Of 9), Other | Other | 2200 | 0.34 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
Z80418 | Z80418 | RAW264.7 (Monocytic-macrophage Leukemia Cells) | 2200 | 0.34 | Functional ≤ 10μM |
Description | Species |
---|---|
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) |