UCSF

ZINC39569538

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
February 28th, 2010 24 Yes

Popular Name: Lysergic Acid Diethylamide Lysergic Acid Diethylamide

Find On: PubMed — Wikipedia — Google

CAS Number: 50-37-3

Other Names:

(+)-LSD

(+)-lysergic acid diethylamide

50-37-3; C07542; LSD; Lysergic acid diethylamide; Lysergide

9,10-Didehydro-N,N-diethyl-6-methylergoline-8b-carboxamide

Acid

Barrels

Bart simpson

Bartman

Beast

Big f

Blotter acid

Blue acid

Blue cheer

Blue mist

Blue star

Brown dots

California sunshine

Cherry top

Chief

Chocolate chips

Clearlight

Coffeinum

Contact lens

Cubes

Cupcakes

D-LSD

D-LSD-25

D-lysergic acid dethylamide

D-lysergic acid diethylamide

D-lysergic acid n,n-diethylamide

Delysid

Dextrolysergic acid diethylamide

Diethylamid kyseliny lysergove

Diethylamid kyseliny lysergove [czech]

DNC008882

Domes

Ergine

Ergoline-8-beta-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl-, tartrate (1:1), d-; LS-64353; d-9,10-Didehydro-N,N-diethyl-6-methylergoline-8-beta-carboxamide tartrate (1:1); d-Lsd 25 bitartrate; d-Lysergic acid diethylamide bitartrate

Fifty

Flats

Frogs

Gelatin chips

Greenies

Heavenly blue

LSD

LSD-25

Lucy in the sky with diamonds

Lysergamid

Lysergamide

Lysergaure diethylamid

Lysergic acid amide

Lysergic acid diethylamide-25

Lysergide

Lysergidum

Lysergidum [inn-latin]

Mean green

Mellow yellow

Microdots

n,n-diethyl-(+)-lysergamide

N,N-Diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide

N,n-diethyl-d-lysergamide

N,n-diethyllysergamide

Orange mushroom

Orange sunshine

Orange wedges

Owsley

Paper acid

Pearly gates

Purple haze

Purple microdot

Royal blue

Scapes

Spoonies

Strawberry fields

Sugar

Sugar lump

Sunshine

TABS

The hawk

TMA

Trippers

Ubergluben

Wedding bells

Wedges

White light

Window pane

Yellows

ZEN

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 9.56 -39.99 1 4 1 37 324.448 3 ↓
Hi High (pH 8-9.5) 2.33 7.36 -11.18 0 4 0 36 323.44 3 ↓
Lo Low (pH 4.5-6) 2.33 10.01 -90.93 2 4 2 39 325.456 3 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 2.70e-01 g/l DrugBank-withdrawn
PUBCHEM_PATENT_ID EP0816364A1 IBM Patent Data

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
5HT2A-1-E Serotonin 2a (5-HT2a) Receptor (cluster #1 Of 3), Eukaryotic Eukaryotes 21 0.45 Binding ≤ 10μM
5HT2C-1-E Serotonin 2c (5-HT2c) Receptor (cluster #1 Of 3), Eukaryotic Eukaryotes 53 0.42 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
5HT2A_HUMAN P28223 Serotonin 2a (5-HT2a) Receptor, Human 21.17 0.45 Binding ≤ 1μM
5HT2C_HUMAN P28335 Serotonin 2c (5-HT2c) Receptor, Human 52.84 0.42 Binding ≤ 1μM
5HT2A_HUMAN P28223 Serotonin 2a (5-HT2a) Receptor, Human 21.17 0.45 Binding ≤ 10μM
5HT2C_HUMAN P28335 Serotonin 2c (5-HT2c) Receptor, Human 52.84 0.42 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
G alpha (q) signalling events
Serotonin receptors

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.