UCSF

Angiotensin II Type 1a (AT-1a) Receptor, Rat (1,227 Compounds)

Swissprot:
AGTRA_RAT
Stitch:
AGTRA_RAT
UniProt:
P25095
ChEMBL:
CHEMBL329
Reactome:
REACT_263374
REACT_250028
PDB:
2AC6 (DOCK)
2AH3 (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,227 13 11 10
Binding ≤ 1μM 1,065 13 11 10
Functional ≤ 10μM 22 1 2 2

Reactome Network (2)

Reactome ID Description Species
REACT_263374 G alpha (q) signalling events Rattus norvegicus
REACT_250028 Peptide ligand-binding receptors Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
AGTRB_RAT P29089 CHEMBL263 Angiotensin II Type 1b (AT-1b) Receptor, Rat 1189

Peptide ligand-binding receptors

Uniprot Swissprot Chembl Description Number Shared
AGTR2_RAT P35351 CHEMBL257 Angiotensin II Type 2 (AT-2) Receptor, Rat 495
AGTRB_RAT P29089 CHEMBL263 Angiotensin II Type 1b (AT-1b) Receptor, Rat 1189

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
AGTRB_RAT P29089 CHEMBL263 Angiotensin II Type 1b (AT-1b) Receptor, Rat 1189
AGTR2_RAT P35351 CHEMBL257 Angiotensin II Type 2 (AT-2) Receptor, Rat 494
AGTR2_HUMAN P50052 CHEMBL4607 Angiotensin II Type 2 (AT-2) Receptor, Human 175
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 155
AGTR1_RABIT P34976 CHEMBL3948 Angiotensin II Type 1a (AT-1a) Receptor, Rabit 58
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 25
AGTR1_BOVIN P25104 CHEMBL3374 Angiotensin II Type 1a (AT-1a) Receptor, Bovin 10
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 8
AGTR1_PIG P30555 CHEMBL5743 Type-1 Angiotensin II Receptor, Pig 2
ACE_HUMAN P12821 CHEMBL1808 Angiotensin-converting Enzyme, Human 1
AGTR1_CAVPO Q9WV26 CHEMBL1671613 Type-1 Angiotensin II Receptor, Guinea Pig 1
Q2XUH7_PIG Q2XUH7 CHEMBL1163122 Angiotensin Type II Receptor, Pig 1
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z80902 Z80902 CHEMBL614150 HASMC (Aortic Smooth Muscle Cells) 1

Most Common Rings