UCSF

Beta-lactamase, Entcl (108 Compounds)

Swissprot:
AMPC_ENTCL
Stitch:
AMPC_ENTCL
UniProt:
P05364
ChEMBL:
CHEMBL2725
PDB:
1BLS (DOCK)
1GCE (DOCK)
1RGZ (DOCK)
1XX2 (DOCK)
1Y54 (DOCK)
2Q9M (DOCK)
2Q9N (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 108 8 4 5
Binding ≤ 1μM 87 5 4 5
Functional ≤ 10μM 17 1 1 1

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
AMPC_CITFR P05193 CHEMBL1255130 Beta-lactamase, Citfr 7 1 1 1
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 108 28 15 16
AMPC_MORMO P94958 CHEMBL5764 Beta-lactamase, Mormo 1 1 1 1
AMPC_PSEAE P24735 CHEMBL5031 Beta-lactamase, Pseae 60 2 2 3

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
AMPC-1-B Beta-lactamase (cluster #1 Of 6), Bacterial 20 13 10 9
AMPC-2-B Beta-lactamase (cluster #2 Of 6), Bacterial 22 8 3 4
AMPC-3-B Beta-lactamase (cluster #3 Of 6), Bacterial 0 0 0 0
AMPC-4-B Beta-lactamase (cluster #4 Of 6), Bacterial 0 0 0 0
AMPC-5-B Beta-lactamase (cluster #5 Of 6), Bacterial 185 8 3 4
AMPC-6-B Beta-lactamase (cluster #6 Of 6), Bacterial 6 4 0 1
Uniprot Swissprot Chembl Description Number Shared
BLAT_ECOLX P62593 CHEMBL2065 Beta-lactamase TEM, Ecolx 48
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 28
BLAB_BACFR P25910 CHEMBL4840 Beta-lactamase Type II, Bacfr 21
AMPC_PSEAE P24735 CHEMBL5031 Beta-lactamase, Pseae 13
BLAN_ENTCL P52663 CHEMBL4314 Imipenem-hydrolyzing Beta-lactamase, Entcl 13
BLA1_ECOLX P0AD63 CHEMBL5956 Beta-lactamase SHV-1, Ecolx 11
BLAC_STAAU P00807 CHEMBL4114 Beta-lactamase, Staau 10
Z50270 Z50270 CHEMBL612626 Bacillus Licheniformis 10
Z50145 Z50145 CHEMBL349 Enterobacter Cloacae 4
Q59401_ENTCL Q59401 CHEMBL3499 Beta-lactamase Class C, Entcl 3
Q6W9J1_ENTCL Q6W9J1 CHEMBL3652 Beta-lactamase TEM, Entcl 3
Z50208 Z50208 CHEMBL612615 Citrobacter Freundii 3
A1E3K9_ECOLX A1E3K9 CHEMBL1075073 Beta-lactamase SCO-1, Ecolx 2
A8RR46_BACCS A8RR46 CHEMBL5439 Beta-lactamase, Baccs 2
AMPC_CITFR P05193 CHEMBL1255130 Beta-lactamase, Citfr 2
BLAC_BACLI P00808 CHEMBL5633 Beta-lactamase, Bacli 2
BLO1_ECOLX P13661 CHEMBL4951 Beta-lactamase OXA-1, Ecolx 2
CTRA_BOVIN P00766 CHEMBL3314 Alpha-chymotrypsin, Bovin 2
D1MIX9_PSEAI D1MIX9 CHEMBL1250341 Beta-lactamase GES-13, Pseai 2
MDHM_PIG P00346 CHEMBL3444 Malate Dehydrogenase Mitochondrial, Pig 2
Q46991_ENTCL Q46991 CHEMBL5219 IMI-1, Entcl 2
A0ZX81_KLEPN A0ZX81 CHEMBL1255121 Beta-lactamase, Klepn 1
A2RP81_CITFR A2RP81 CHEMBL5303 PER-2 Beta-lactamase, Citfr 1
A4KCT8_9ENTR A4KCT8 CHEMBL1075063 Gil1, 9entr 1
ABCC8_HUMAN Q09428 CHEMBL2071 Sulfonylurea Receptor 1, Human 1
ABCC9_HUMAN O60706 CHEMBL1971 Sulfonylurea Receptor 2, Human 1
ABCC9_RAT Q63563 CHEMBL3244 Sulfonylurea Receptor 2, Rat 1
AMPC_MORMO P94958 CHEMBL5764 Beta-lactamase, Mormo 1
B8R6A5_9BURK B8R6A5 CHEMBL1641339 PenB Class A Beta-lactamase, 9burk 1
BLA1_KLEPN P0AD64 CHEMBL5094 Beta-lactamase SHV-1, Klepn 1
BLKPC_KLEPN Q9F663 CHEMBL6132 Carbepenem-hydrolyzing Beta-lactamase KPC, Klepn 1
BLO2_ECOLX P0A1V9 CHEMBL1744485 Beta-lactamase OXA-2, Ecolx 1
D5HSX5_9GAMM D5HSX5 CHEMBL1697666 Extended-spectrum Beta-lactamase PER-6, 9gamm 1
IRK11_HUMAN Q14654 CHEMBL1886 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 11, Human 1
IRK11_RAT P70673 CHEMBL3704 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 11, Rat 1
IRK8_RAT Q63664 CHEMBL4293 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 8, Rat 1
KCND3_HUMAN Q9UK17 CHEMBL1964 Voltage-gated Potassium Channel Subunit Kv4.3, Human 1
LACTB_HUMAN P83111 CHEMBL3791 Serine Beta-lactamase-like Protein, Human 1
Q0VTR6_ACIG3 Q0VTR6 CHEMBL1667675 ADC-14 Protein, Acig3 1
Q0VTR8_ACIG3 Q0VTR8 CHEMBL1667676 ADC-16 Protein, Acig3 1
Q2V0Y6_ECOLX Q2V0Y6 CHEMBL1744490 Beta-lactamase, Ecolx 1
Q2XPY6_SALET Q2XPY6 CHEMBL1667678 Extended-spectrum Beta-lactamase CTX-M-53, Salet 1
Q50H31_BRAPL Q50H31 CHEMBL1255145 Class D Beta-lactamase, Brapl 1
Q53729_STAAU Q53729 CHEMBL3825 Penicillin-binding Protein 2, Staau 1
Q6GWS8_ECOLX Q6GWS8 CHEMBL5041 Beta-lactamase TEM-125, Ecolx 1
Q6JP75_SERFO Q6JP75 CHEMBL5042 Carbapenem-hydrolizing Beta-lactamase SFC-1, Serfo 1
Q7X575_ECOLX Q7X575 CHEMBL1287606 Beta-lactamase SHV-11, Ecolx 1
Q9EXV5_ECOLX Q9EXV5 CHEMBL6131 Beta-lactamase, Ecolx 1
Z50117 Z50117 CHEMBL348 Pseudomonas Aeruginosa 1
Z50185 Z50185 CHEMBL352 Staphylococcus Aureus 1
Z50212 Z50212 CHEMBL354 Escherichia Coli 1