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APEX1_HUMAN - DNA-(apurinic Or Apyrimidinic Site) Lyase, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

DNA-(apurinic Or Apyrimidinic Site) Lyase, Human (38 Compounds)

Swissprot:
APEX1_HUMAN
Stitch:
APEX1_HUMAN
UniProt:
P27695
ChEMBL:
CHEMBL5619
Reactome:
REACT_1357
REACT_1064
REACT_2192
REACT_1128
PDB:
1BIX (DOCK)
1CQG (DOCK)
1CQH (DOCK)
1DE8 (DOCK)
1DE9 (DOCK)
1DEW (DOCK)
1E9N (DOCK)
1HD7 (DOCK)
2ISI (DOCK)
2O3H (DOCK)
3U8U (DOCK)
APEX1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 38 18 4 0
Binding ≤ 1μM 5 0 0 0

Reactome Network (4)

Reactome ID Description Species
REACT_1357 Base-free sugar-phosphate removal via the single-nucleotide replacement pathway Homo sapiens
REACT_1064 Displacement of DNA glycosylase by APE1 Homo sapiens
REACT_2192 Removal of DNA patch containing abasic residue Homo sapiens
REACT_1128 Resolution of AP sites via the multiple-nucleotide patch replacement pathway Homo sapiens

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
APEX1-1-E DNA-(apurinic Or Apyrimidinic Site) Lyase (cluster #1 Of 2), Eukaryotic 27 10 0 0
APEX1-2-E DNA-(apurinic Or Apyrimidinic Site) Lyase (cluster #2 Of 2), Eukaryotic 11 8 4 0

Most Common Rings