UCSF

Carbonic Anhydrase VI, Human (137 Compounds)

Swissprot:
CAH6_HUMAN
Stitch:
CAH6_HUMAN
UniProt:
P23280
ChEMBL:
CHEMBL3025
Reactome:
REACT_121123
PDB:
3FE4 (DOCK)
CA6

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 137 86 58 61
Binding ≤ 1μM 84 45 27 33

Reactome Network (1)

Reactome ID Description Species
REACT_121123 Reversible hydration of carbon dioxide Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 126
CAH13_HUMAN Q8N1Q1 CHEMBL3912 Carbonic Anhydrase XIII, Human 56
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 113
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 114
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 123
CAH3_HUMAN P07451 CHEMBL2885 Carbonic Anhydrase III, Human 63
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 113
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 118
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 120
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 123
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 129
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CAH6_BOVIN P18915 CHEMBL4891 Carbonic Anhydrase VI, Bovin 18 1 1 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CAH10_HUMAN Q9NS85 CHEMBL4645 Carbonic Anhydrase-related Protein 10, Human 27 7 1 1
CAH11_HUMAN O75493 CHEMBL2420 Carbonic Anhydrase-related Protein 2, Human 27 7 1 1
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 544 146 66 65
CAH13_HUMAN Q8N1Q1 CHEMBL3912 Carbonic Anhydrase XIII, Human 85 27 16 18
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 322 95 42 48
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 2,197 284 79 75
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 2,967 379 112 102
CAH3_HUMAN P07451 CHEMBL2885 Carbonic Anhydrase III, Human 76 47 33 28
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 223 84 54 59
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 192 101 50 53
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 176 97 49 53
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 272 116 52 56
CAH8_HUMAN P35219 CHEMBL2410 Carbonic Anhydrase-related Protein 8, Human 27 7 1 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1,000 180 68 64

Clustered By Gene (0)

Clustered By Organism (7)

Code Description Substances Purchasable Natural In Man
CAH6-1-E Carbonic Anhydrase VI (cluster #1 Of 8), Eukaryotic 62 27 19 24
CAH6-2-E Carbonic Anhydrase VI (cluster #2 Of 8), Eukaryotic 23 9 9 10
CAH6-3-E Carbonic Anhydrase VI (cluster #3 Of 8), Eukaryotic 6 6 3 4
CAH6-4-E Carbonic Anhydrase VI (cluster #4 Of 8), Eukaryotic 4 4 3 2
CAH6-5-E Carbonic Anhydrase VI (cluster #5 Of 8), Eukaryotic 1 1 1 0
CAH6-6-E Carbonic Anhydrase VI (cluster #6 Of 8), Eukaryotic 0 0 0 0
CAH6-7-E Carbonic Anhydrase VI (cluster #7 Of 8), Eukaryotic 39 26 14 14
CAH6-8-E Carbonic Anhydrase VI (cluster #8 Of 8), Eukaryotic 18 13 9 7
Uniprot Swissprot Chembl Description Number Shared
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 129
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 126
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 123
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 123
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 120
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 118
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 114
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 113
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 113
CAH15_MOUSE Q99N23 CHEMBL5973 Carbonic Anhydrase 15, Mouse 74
CAH3_HUMAN P07451 CHEMBL2885 Carbonic Anhydrase III, Human 63
CAH13_HUMAN Q8N1Q1 CHEMBL3912 Carbonic Anhydrase XIII, Human 56
CAH13_MOUSE Q9D6N1 CHEMBL2186 Carbonic Anhydrase XIII, Mouse 53
Q5AJ71_CANAL Q5AJ71 CHEMBL5337 Carbonic Anhydrase, Canal 43
B5SU02_9CNID B5SU02 CHEMBL1075028 Alpha Carbonic Anhydrase, 9cnid 38
C0IX24_9CNID C0IX24 CHEMBL1649055 Carbonic Anhydrase, 9cnid 38
CAH4_BOVIN Q95323 CHEMBL281 Carbonic Anhydrase IV, Bovin 37
CYNT_HELPY O24855 CHEMBL4211 Carbonic Anhydrase 1, Helpy 37
CAN_YEAST P53615 CHEMBL5931 Carbonic Anhydrase, Yeast 34
Y1284_MYCTU P64797 CHEMBL5631 Uncharacterized Protein Rv1284/MT1322, Myctu 32
CAH10_HUMAN Q9NS85 CHEMBL4645 Carbonic Anhydrase-related Protein 10, Human 27
CAH11_HUMAN O75493 CHEMBL2420 Carbonic Anhydrase-related Protein 2, Human 27
CAH8_HUMAN P35219 CHEMBL2410 Carbonic Anhydrase-related Protein 8, Human 27
CYNT_MYCTU O53573 CHEMBL6068 Carbonic Anhydrase, Myctu 23
CAH_METTE P40881 CHEMBL3932 Carbonic Anhydrase, Mette 19
P96878_MYCTU P96878 CHEMBL5767 PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), Myctu 14
CAH5A_MOUSE P23589 CHEMBL2330 Carbonic Anhydrase VA, Mouse 10
CAH5B_MOUSE Q9QZA0 CHEMBL4634 Carbonic Anhydrase VB, Mouse 10
PGH1_SHEEP P05979 CHEMBL2949 Cyclooxygenase-1, Sheep 5
Q2PCB5_DICLA Q2PCB5 CHEMBL1795125 Carbonic Anhydrase, Dicla 5
MDR3_MOUSE P21447 CHEMBL2573 P-glycoprotein 3, Mouse 4
Q3I4V7_CRYNV Q3I4V7 CHEMBL1697676 Carbonic Anhydrase 2, Crynv 4
CAH2_BOVIN P00921 CHEMBL2283 Carbonic Anhydrase II, Bovin 3
CAH2_RAT P27139 CHEMBL4706 Carbonic Anhydrase II, Rat 3
CAH3_RAT P14141 CHEMBL4997 Carbonic Anhydrase III, Rat 3
CAH4_RAT P48284 CHEMBL2962 Carbonic Anhydrase IV, Rat 3
CAH5A_RAT P43165 CHEMBL2138 Carbonic Anhydrase VA, Rat 3
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 3
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 3
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 3
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 2
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 2
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 2
CAH6_BOVIN P18915 CHEMBL4891 Carbonic Anhydrase VI, Bovin 2
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 2
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 2
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 2
DDR1_HUMAN Q08345 CHEMBL5319 Epithelial Discoidin Domain-containing Receptor 1, Human 2
DDR2_HUMAN Q16832 CHEMBL5122 Discoidin Domain-containing Receptor 2, Human 2
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 2
DRD2_CANFA Q9GJU1 CHEMBL2703 Dopamine D2 Receptor, Canine 2
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 2
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 2
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 2
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 2
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 2
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 2
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 2
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 2
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 2
LGUL_HUMAN Q04760 CHEMBL2424 Glyoxalase I, Human 2
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 2
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 2
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 2
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 2
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 2
5NTD_RAT P21588 CHEMBL1075214 5'-nucleotidase, Rat 1
A1Z199_HUMAN A1Z199 CHEMBL6105 BCR/ABL P210 Fusion Protein, Human 1
A4_HUMAN P05067 CHEMBL2487 Beta Amyloid A4 Protein, Human 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
ABL1_MOUSE P00520 CHEMBL3099 Tyrosine-protein Kinase ABL, Mouse 1
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 1
AHR_RABIT O02747 CHEMBL4725 Aryl Hydrocarbon Receptor, Rabit 1
AK1A1_RAT P51635 CHEMBL3871 Aldehyde Reductase, Rat 1
AK1CL_MOUSE Q91WR5 CHEMBL1075270 Aldo-keto Reductase Family 1 Member C21, Mouse 1
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 1
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 1
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 1
AMPH_ECOLI P0AD70 CHEMBL4413 Penicillin-binding Protein AmpH, Ecoli 1
AOFA_BOVIN P21398 CHEMBL3254 Monoamine Oxidase A, Bovin 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 1
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 1
AOFB_RAT P19643 CHEMBL2993 Monoamine Oxidase B, Rat 1
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 1
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1
CAH7_MOUSE Q9ERQ8 CHEMBL2216 Carbonic Anhydrase VII, Mouse 1
CASP2_HUMAN P42575 CHEMBL4884 Caspase-2, Human 1
CDK19_HUMAN Q9BWU1 CHEMBL6002 Cell Division Cycle 2-like Protein Kinase 6, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 1
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 1
COX2_HUMAN P00403 CHEMBL6174 Cytochrome C Oxidase Subunit 2, Human 1
COX2_SHEEP O78750 CHEMBL1250404 Cytochrome C Oxidase Subunit 2, Sheep 1
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 1
CSK21_RAT P19139 CHEMBL2661 Casein Kinase II Alpha, Rat 1
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 1
CSK2B_RAT P67874 CHEMBL2463 Casein Kinase II Beta, Rat 1
DHB2_HUMAN P37059 CHEMBL2789 Estradiol 17-beta-dehydrogenase 2, Human 1
DHB3_RAT O54939 CHEMBL1075158 Testosterone 17-beta-dehydrogenase 3, Rat 1
DHI1_HUMAN P28845 CHEMBL4235 11-beta-hydroxysteroid Dehydrogenase 1, Human 1
DHI1_MOUSE P50172 CHEMBL3910 11-beta-hydroxysteroid Dehydrogenase 1, Mouse 1
EPHA8_HUMAN P29322 CHEMBL4134 Ephrin Type-A Receptor 8, Human 1
ERG1_RAT P52020 CHEMBL4241 Squalene Monooxygenase, Rat 1
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 1
FGR_HUMAN P09769 CHEMBL4454 Tyrosine-protein Kinase FGR, Human 1
FGR_RAT Q6P6U0 CHEMBL4362 Tyrosine-protein Kinase FGR, Rat 1
FRK_HUMAN P42685 CHEMBL4223 Tyrosine-protein Kinase FRK, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein Kinase GAK, Human 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 1
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 1
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 1
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 1
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 1
KSYK_RAT Q64725 CHEMBL4364 Tyrosine-protein Kinase SYK, Rat 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 1
LOX12_HUMAN P18054 CHEMBL3687 Arachidonate 12-lipoxygenase, Human 1
LOX15_HUMAN P16050 CHEMBL2903 Arachidonate 15-lipoxygenase, Human 1
LOX15_RABIT P12530 CHEMBL4358 Arachidonate 15-lipoxygenase, Rabit 1
LOX1_SOYBN P08170 CHEMBL4586 Seed Lipoxygenase-1, Soybn 1
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 1
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1
LYN_RAT Q07014 CHEMBL4363 Tyrosine-protein Kinase Lyn, Rat 1
MDH_THETH P10584 CHEMBL4255 Malate Dehydrogenase, Theth 1
MELK_HUMAN Q14680 CHEMBL4578 Maternal Embryonic Leucine Zipper Kinase, Human 1
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 1
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 1
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
MLTK_HUMAN Q9NYL2 CHEMBL3886 Mixed Lineage Kinase 7, Human 1
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 1
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 1
MTSI_SPISQ P15840 CHEMBL4373 CpG DNA Methylase, Spisq 1
NANH_CLOPE P10481 CHEMBL5189 Sialidase, Clope 1
NOS2_HUMAN P35228 CHEMBL4481 Nitric Oxide Synthase, Inducible, Human 1
NOX4_HUMAN Q9NPH5 CHEMBL1250375 NADPH Oxidase 4, Human 1
NQO2_HUMAN P16083 CHEMBL3959 Quinone Reductase 2, Human 1
O49150_SOLTU O49150 CHEMBL3317 5-lipoxygenase, Soltu 1
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 1
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 1
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 1
PGH1_BOVIN O62664 CHEMBL2860 Cyclooxygenase-1, Bovin 1
PGH1_MOUSE P22437 CHEMBL2649 Cyclooxygenase-1, Mouse 1
PGH2_BOVIN O62698 CHEMBL3331 Cyclooxygenase-2, Bovin 1
PGH2_MOUSE Q05769 CHEMBL4321 Cyclooxygenase-2, Mouse 1
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2, Rat 1
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 1
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 1
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 1
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 1
PTN1_HUMAN P18031 CHEMBL335 Protein-tyrosine Phosphatase 1B, Human 1
Q43570_TOBAC Q43570 CHEMBL1293200 Zn Finger Protein, Tobac 1
Q50565_METTH Q50565 CHEMBL3926 Carbonic Anhydrase, Metth 1
Q6FTL6_CANGA Q6FTL6 CHEMBL6185 Carbonic Anhydrase, Canga 1
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 1
Q8HY88_BOVIN Q8HY88 CHEMBL1075183 Potassium Channel Subfamily K Member 2, Bovin 1
Q8HZR1_CANFA Q8HZR1 CHEMBL4133 Cyclooxygenase-1, Canine 1
Q8SPQ9_CANFA Q8SPQ9 CHEMBL4033 Cyclooxygenase-2, Canine 1
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 1
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 1
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 1
R1AB_CVHSA P0C6X7 CHEMBL5118 Replicase Polyprotein 1ab, Cvhsa 1
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 1
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein Kinase 17A, Human 1
STS_HUMAN P08842 CHEMBL3559 Steryl-sulfatase Precursor, Human 1
TNI3K_HUMAN Q59H18 CHEMBL5260 Serine/threonine-protein Kinase TNNI3K, Human 1
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 1
XDH_BOVIN P80457 CHEMBL3649 Xanthine Dehydrogenase, Bovin 1
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 1
Z100250 Z100250 CHEMBL612514 Calf Thymus DNA 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1

Most Common Rings