UCSF

Caspase-2, Human (75 Compounds)

Swissprot:
CASP2_HUMAN
Stitch:
CASP2_HUMAN
UniProt:
P42575
ChEMBL:
CHEMBL4884
Reactome:
REACT_13526
REACT_75776
PDB:
1PYO (DOCK)
2P2C (DOCK)
3R5J (DOCK)
3R6G (DOCK)
3R6L (DOCK)
3R7B (DOCK)
3R7N (DOCK)
3R7S (DOCK)
3RJM (DOCK)
CASP2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 75 2 1 2
Binding ≤ 1μM 61 0 0 1

Reactome Network (2)

Uniprot Swissprot Chembl Description Number Shared
CASP3_HUMAN P42574 CHEMBL2334 Caspase-3, Human 62

NOD1/2 Signaling Pathway

Uniprot Swissprot Chembl Description Number Shared
CASP1_HUMAN P29466 CHEMBL4801 Caspase-1, Human 2
CASP8_HUMAN Q14790 CHEMBL3776 Caspase-8, Human 9
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CASP1_HUMAN P29466 CHEMBL4801 Caspase-1, Human 975 16 2 1
CASP3_HUMAN P42574 CHEMBL2334 Caspase-3, Human 987 29 1 5
CASP4_HUMAN P49662 CHEMBL2226 Caspase-4, Human 5 0 0 0
CASP5_HUMAN P51878 CHEMBL3131 Caspase-5, Human 4 0 0 0
CASP6_HUMAN P55212 CHEMBL3308 Caspase-6, Human 171 7 0 1
CASP7_HUMAN P55210 CHEMBL3468 Caspase-7, Human 433 10 0 2
CASP8_HUMAN Q14790 CHEMBL3776 Caspase-8, Human 444 4 1 2
CASP9_HUMAN P55211 CHEMBL2273 Caspase-9, Human 11 2 0 0
CASPA_HUMAN Q92851 CHEMBL5037 Caspase-10, Human 4 0 0 0
CASPE_HUMAN P31944 CHEMBL5991 Caspase-14, Human 1 0 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
CASP2-1-E Caspase-2 (cluster #1 Of 3), Eukaryotic 64 0 0 0
CASP2-2-E Caspase-2 (cluster #2 Of 3), Eukaryotic 10 1 0 1
CASP2-3-E Caspase-2 (cluster #3 Of 3), Eukaryotic 1 1 1 1
Uniprot Swissprot Chembl Description Number Shared
CASP3_HUMAN P42574 CHEMBL2334 Caspase-3, Human 62
CASP6_HUMAN P55212 CHEMBL3308 Caspase-6, Human 10
CASP7_HUMAN P55210 CHEMBL3468 Caspase-7, Human 10
CASP8_HUMAN Q14790 CHEMBL3776 Caspase-8, Human 9
CASP1_HUMAN P29466 CHEMBL4801 Caspase-1, Human 2
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
Z100250 Z100250 CHEMBL612514 Calf Thymus DNA 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1