ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (41)
Reactome (3)
Related By:
Pathway (0)
Organism (2)
Gene (0)
Org. Clust. (2)
ChEMBL (8)
Rings (5)

DNA Polymerase Beta, Human (41 Compounds)

Swissprot:: DPOLB_HUMAN
Stitch:: DPOLB_HUMAN
UniProt:: P06746
ChEMBL:: CHEMBL2392
Reactome:: REACT_1357; REACT_2192; REACT_933
PDB:: 1BPX (DOCK); 1BPY (DOCK); 1BPZ (DOCK); 1MQ2 (DOCK); 1MQ3 (DOCK); 1TV9 (DOCK); 1TVA (DOCK); 1ZJM (DOCK); 1ZJN (DOCK); 1ZQA (DOCK); 1ZQB (DOCK); 1ZQC (DOCK); 1ZQD (DOCK); 1ZQE (DOCK); 1ZQF (DOCK); 1ZQG (DOCK); 1ZQH (DOCK); 1ZQI (DOCK); 1ZQJ (DOCK); 1ZQK (DOCK); 1ZQL (DOCK); 1ZQM (DOCK); 1ZQN (DOCK); 1ZQO (DOCK); 1ZQP (DOCK); 1ZQQ (DOCK); 1ZQR (DOCK); 1ZQS (DOCK); 1ZQT (DOCK); 2FMP (DOCK); 2FMQ (DOCK); 2FMS (DOCK); 2I9G (DOCK); 2ISO (DOCK); 2ISP (DOCK); 2P66 (DOCK); 2PXI (DOCK); 3C2K (DOCK); 3C2L (DOCK); 3C2M (DOCK); 3GDX (DOCK); 3ISB (DOCK); 3ISC (DOCK); 3ISD (DOCK); 3JPN (DOCK); 3JPO (DOCK); 3JPP (DOCK); 3JPQ (DOCK); 3JPR (DOCK); 3JPS (DOCK); 3JPT (DOCK); 3LK9 (DOCK); 3MBY (DOCK); 3OGU (DOCK); 3RH4 (DOCK); 3RH5 (DOCK); 3RH6 (DOCK); 3RJE (DOCK); 3RJF (DOCK); 3RJG (DOCK); 3RJH (DOCK); 3RJI (DOCK); 3RJJ (DOCK); 3RJK (DOCK); 7ICE (DOCK); 7ICF (DOCK); 7ICG (DOCK); 7ICH (DOCK); 7ICI (DOCK); 7ICJ (DOCK); 7ICK (DOCK); 7ICL (DOCK); 7ICM (DOCK); 7ICN (DOCK); 7ICO (DOCK); 7ICP (DOCK); 7ICQ (DOCK); 7ICR (DOCK); 7ICS (DOCK); 7ICT (DOCK); 7ICU (DOCK); 7ICV (DOCK); 8ICA (DOCK); 8ICB (DOCK); 8ICC (DOCK); 8ICE (DOCK); 8ICF (DOCK); 8ICG (DOCK); 8ICH (DOCK); 8ICI (DOCK); 8ICJ (DOCK); 8ICK (DOCK); 8ICL (DOCK); 8ICM (DOCK); 8ICN (DOCK); 8ICO (DOCK); 8ICP (DOCK); 8ICQ (DOCK); 8ICR (DOCK); 8ICS (DOCK); 8ICT (DOCK); 8ICU (DOCK); 8ICV (DOCK); 8ICW (DOCK); 8ICX (DOCK); 8ICY (DOCK); 8ICZ (DOCK); 9ICA (DOCK); 9ICB (DOCK); 9ICC (DOCK); 9ICE (DOCK); 9ICF (DOCK); 9ICG (DOCK); 9ICH (DOCK); 9ICI (DOCK); 9ICJ (DOCK); 9ICK (DOCK); 9ICL (DOCK); 9ICM (DOCK); 9ICN (DOCK); 9ICO (DOCK); 9ICP (DOCK); 9ICQ (DOCK); 9ICR (DOCK); 9ICS (DOCK); 9ICT (DOCK); 9ICU (DOCK); 9ICV (DOCK); 9ICW (DOCK); 9ICX (DOCK); 9ICY (DOCK); POLB

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	41	5	1	0
Binding ≤ 1μM	12	0	0	0

Reactome ID	Description	Species
REACT_1357	Base-free sugar-phosphate removal via the single-nucleotide replacement pathway	Homo sapiens
REACT_2192	Removal of DNA patch containing abasic residue	Homo sapiens
REACT_933	Resolution of AP sites via the single-nucleotide replacement pathway	Homo sapiens

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
DPOLB_MOUSE	Q8K409	CHEMBL4565	DNA Polymerase Beta, Mouse	0	0	0	0
DPOLB_RAT	P06766	CHEMBL4343	DNA Polymerase Beta, Rat	18	8	9	0

Clustered By Gene (0)

Clustered By Organism (2)

Code	Description	Substances	Purchasable	Natural
DPOLB-1-E	DNA Polymerase Beta (cluster #1 Of 3), Eukaryotic	31	4	0
DPOLB-2-E	DNA Polymerase Beta (cluster #2 Of 3), Eukaryotic	21	5	4
DPOLB-3-E	DNA Polymerase Beta (cluster #3 Of 3), Eukaryotic	6	3	5

Uniprot	Swissprot	Chembl	Description	Number Shared
DPOLA_HUMAN	P09884	CHEMBL1828	DNA Polymerase Alpha Subunit, Human	24
DPOG1_HUMAN	P54098	CHEMBL2732	DNA Polymerase Gamma Subunit 1, Human	16
Q72547_9HIV1	Q72547	CHEMBL247	Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1	16
Z50606	Z50606	CHEMBL613497	Hepatitis B Virus	12
TDT_HUMAN	P04053	CHEMBL4810	Terminal Deoxynucleotidyltransferase, Human	2
DPOLB_RAT	P06766	CHEMBL4343	DNA Polymerase Beta, Rat	1
PTN1_HUMAN	P18031	CHEMBL335	Protein-tyrosine Phosphatase 1B, Human	1
PTN2_HUMAN	P17706	CHEMBL3807	T-cell Protein-tyrosine Phosphatase, Human	1