| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 13 | 4 | 2 | 0 |
| Binding ≤ 1μM | 11 | 3 | 1 | 0 |
| Functional ≤ 10μM | 9 | 5 | 3 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_15525 | Nuclear Receptor transcription pathway | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ERR1_HUMAN | P11474 | CHEMBL3429 | Estrogen-related Receptor Alpha, Human | 1 |
| ERR2_HUMAN | O95718 | CHEMBL3751 | Estrogen-related Receptor Beta, Human | 1 |
| ESR1_HUMAN | P03372 | CHEMBL206 | Estrogen Receptor Alpha, Human | 13 |
| ESR2_HUMAN | Q92731 | CHEMBL242 | Estrogen Receptor Beta, Human | 3 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| ERR1_HUMAN | P11474 | CHEMBL3429 | Estrogen-related Receptor Alpha, Human | 41 | 2 | 3 | 3 |
| ERR2_HUMAN | O95718 | CHEMBL3751 | Estrogen-related Receptor Beta, Human | 21 | 2 | 2 | 2 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ESR1_HUMAN | P03372 | CHEMBL206 | Estrogen Receptor Alpha, Human | 12 |
| Z80224 | Z80224 | CHEMBL387 | MCF7 (Breast Carcinoma Cells) | 2 |
| ERR1_HUMAN | P11474 | CHEMBL3429 | Estrogen-related Receptor Alpha, Human | 1 |
| ERR2_HUMAN | O95718 | CHEMBL3751 | Estrogen-related Receptor Beta, Human | 1 |
| ESR1_RAT | P06211 | CHEMBL2724 | Estrogen Receptor Alpha, Rat | 1 |
| ESR2_HUMAN | Q92731 | CHEMBL242 | Estrogen Receptor Beta, Human | 1 |
| ESR2_RAT | Q62986 | CHEMBL3021 | Estrogen Receptor Beta, Rat | 1 |
| PLD1_HUMAN | Q13393 | CHEMBL2536 | Phospholipase D1, Human | 1 |
| PLD2_HUMAN | O14939 | CHEMBL2734 | Phospholipase D2, Human | 1 |
| Z80005 | Z80005 | CHEMBL614077 | 3T3 (Fibroblast Cells) | 1 |
| Z80030 | Z80030 | CHEMBL614520 | ANN-1 | 1 |
| Z80296 | Z80296 | CHEMBL614185 | MVLN | 1 |
| Z80561 | Z80561 | CHEMBL615023 | U2OS (Osteosarcoma Cells) | 1 |