UCSF

Acyl Coenzyme A:cholesterol Acyltransferase, Rabit (50 Compounds)

Swissprot:
EST1_RABIT
Stitch:
EST1_RABIT
UniProt:
P12337
ChEMBL:
CHEMBL2623
PDB:
1K4Y (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 50 41 13 1
Binding ≤ 1μM 43 34 9 1
Functional ≤ 10μM 39 0 0 0

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
EST1_HUMAN P23141 CHEMBL2265 Acyl Coenzyme A:cholesterol Acyltransferase, Human 254 88 22 5
EST1_PIG Q29550 CHEMBL3383 Carboxylesterase, Pig 31 2 2 2

Clustered By Gene (0)

Clustered By Organism (6)

Code Description Substances Purchasable Natural In Man
EST1-1-E Carboxylesterase (cluster #1 Of 7), Eukaryotic 85 32 4 2
EST1-2-E Carboxylesterase (cluster #2 Of 7), Eukaryotic 23 8 1 0
EST1-3-E Carboxylesterase (cluster #3 Of 7), Eukaryotic 2 2 1 0
EST1-4-E Carboxylesterase (cluster #4 Of 7), Eukaryotic 3 3 1 0
EST1-5-E Carboxylesterase (cluster #5 Of 7), Eukaryotic 37 1 0 1
EST1-6-E Carboxylesterase (cluster #6 Of 7), Eukaryotic 126 48 16 3
EST1-7-E Carboxylesterase (cluster #7 Of 7), Eukaryotic 7 1 1 1
Uniprot Swissprot Chembl Description Number Shared
EST2_HUMAN O00748 CHEMBL3180 Carboxylesterase 2, Human 45
EST1_HUMAN P23141 CHEMBL2265 Acyl Coenzyme A:cholesterol Acyltransferase, Human 42
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 2
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 2
SOAT1_RAT O70536 CHEMBL285 Acyl Coenzyme A:cholesterol Acyltransferase 1, Rat 2
EST1_PIG Q29550 CHEMBL3383 Carboxylesterase, Pig 1