UCSF

Fibrinogen Beta Chain, Human (1 Compounds)

Swissprot:
FIBB_HUMAN
Stitch:
FIBB_HUMAN
UniProt:
P02675
ChEMBL:
CHEMBL2048
Reactome:
REACT_1439
REACT_15443
REACT_15523
REACT_13552
REACT_15381
REACT_318
PDB:
1FZA (DOCK)
1FZB (DOCK)
1FZC (DOCK)
1FZE (DOCK)
1FZF (DOCK)
1FZG (DOCK)
1LT9 (DOCK)
1LTJ (DOCK)
1N86 (DOCK)
1N8E (DOCK)
1RE3 (DOCK)
1RE4 (DOCK)
1RF0 (DOCK)
1RF1 (DOCK)
2A45 (DOCK)
2FFD (DOCK)
2H43 (DOCK)
2HLO (DOCK)
2HOD (DOCK)
2HPC (DOCK)
2OYH (DOCK)
2OYI (DOCK)
2Q9I (DOCK)
2XNX (DOCK)
2XNY (DOCK)
2Z4E (DOCK)
3BVH (DOCK)
3E1I (DOCK)
3GHG (DOCK)
3H32 (DOCK)
3HUS (DOCK)
FGB

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1 0 0 0
Binding ≤ 1μM 1 0 0 0

Reactome Network (6)

Reactome ID Description Species
REACT_1439 Common Pathway Homo sapiens
REACT_15443 GRB2:SOS provides linkage to MAPK signaling for Integrins Homo sapiens
REACT_15523 Integrin alphaIIb beta3 signaling Homo sapiens
REACT_13552 Integrin cell surface interactions Homo sapiens
REACT_15381 p130Cas linkage to MAPK signaling for integrins Homo sapiens
REACT_318 Platelet degranulation Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 1
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 1

Integrin alphaIIb beta3 signaling

Uniprot Swissprot Chembl Description Number Shared
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 1
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 1

Integrin cell surface interactions

Uniprot Swissprot Chembl Description Number Shared
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 1
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 1
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 1
ITB5_HUMAN P18084 CHEMBL2600 Integrin Beta-5, Human 1

p130Cas linkage to MAPK signaling for integrins

Uniprot Swissprot Chembl Description Number Shared
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 1
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 1

Platelet degranulation

Uniprot Swissprot Chembl Description Number Shared
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 1
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 1
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 1
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 1
ITB5_HUMAN P18084 CHEMBL2600 Integrin Beta-5, Human 1
Z104292 Z104292 CHEMBL1907598 Integrin Alpha-V/beta-3 1

Most Common Rings