UCSF

Tyrosine-protein Kinase FYN, Mouse (1 Compounds)

Swissprot:
FYN_MOUSE
Stitch:
FYN_MOUSE
UniProt:
P39688
ChEMBL:
CHEMBL4517
Reactome:
REACT_188194
REACT_204081
REACT_226151
REACT_261451
REACT_225233
REACT_196588
REACT_244852
REACT_261568
REACT_188185
REACT_248291
REACT_243590
REACT_258158
REACT_243939
REACT_257656
REACT_241951
REACT_196487
REACT_220092
REACT_237796
REACT_257032
REACT_253341
REACT_226341
REACT_225107
REACT_227425
REACT_198634
REACT_213364
REACT_254306
REACT_246154
REACT_188578
REACT_257088
PDB:
3UF4 (DOCK)
Fyn

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1 0 0 0
Binding ≤ 1μM 1 0 0 0

Reactome Network (29)

Reactome ID Description Species
REACT_188194 Antigen activates B Cell Receptor (BCR) leading to generation of second messenge Mus musculus
REACT_204081 CD28 co-stimulation Mus musculus
REACT_226151 CD28 dependent PI3K/Akt signaling Mus musculus
REACT_261451 CD28 dependent Vav1 pathway Mus musculus
REACT_225233 Cell surface interactions at the vascular wall Mus musculus
REACT_196588 Constitutive PI3K/AKT Signaling in Cancer Mus musculus
REACT_244852 CRMPs in Sema3A signaling Mus musculus
REACT_261568 CTLA4 inhibitory signaling Mus musculus
REACT_188185 DAP12 signaling Mus musculus
REACT_248291 DCC mediated attractive signaling Mus musculus
REACT_243590 EPH-ephrin mediated repulsion of cells Mus musculus
REACT_258158 EPH-Ephrin signaling Mus musculus
REACT_243939 EPHA-mediated growth cone collapse Mus musculus
REACT_257656 EPHB-mediated forward signaling Mus musculus
REACT_241951 Ephrin signaling Mus musculus
REACT_196487 FCGR activation Mus musculus
REACT_220092 GPVI-mediated activation cascade Mus musculus
REACT_237796 NCAM signaling for neurite out-growth Mus musculus
REACT_257032 Nephrin interactions Mus musculus
REACT_253341 Netrin mediated repulsion signals Mus musculus
REACT_226341 PIP3 activates AKT signaling Mus musculus
REACT_225107 Platelet Adhesion to exposed collagen Mus musculus
REACT_227425 Regulation of KIT signaling Mus musculus
REACT_198634 Regulation of signaling by CBL Mus musculus
REACT_213364 Role of LAT2/NTAL/LAB on calcium mobilization Mus musculus
REACT_254306 Sema3A PAK dependent Axon repulsion Mus musculus
REACT_246154 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Mus musculus
REACT_188578 Signaling by SCF-KIT Mus musculus
REACT_257088 VEGFA-VEGFR2 Pathway Mus musculus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 80 35 14 16

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
FYN-1-E Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic 67 27 10 15
FYN-2-E Tyrosine-protein Kinase FYN (cluster #2 Of 5), Eukaryotic 1 1 0 0
FYN-3-E Tyrosine-protein Kinase FYN (cluster #3 Of 5), Eukaryotic 2 2 1 0
FYN-4-E Tyrosine-protein Kinase FYN (cluster #4 Of 5), Eukaryotic 10 4 2 0
FYN-5-E Tyrosine-protein Kinase FYN (cluster #5 Of 5), Eukaryotic 1 1 1 1
Uniprot Swissprot Chembl Description Number Shared
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 1