UCSF

Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human (6 Compounds)

Swissprot:
GNAI1_HUMAN
Stitch:
GNAI1_HUMAN
UniProt:
P63096
ChEMBL:
CHEMBL4741
Reactome:
REACT_15333
REACT_20653
REACT_18339
REACT_19231
REACT_19327
REACT_19333
REACT_15457
REACT_15426
REACT_18325
PDB:
1KJY (DOCK)
1Y3A (DOCK)
2EBC (DOCK)
2G83 (DOCK)
2GTP (DOCK)
2HLB (DOCK)
2IK8 (DOCK)
2OM2 (DOCK)
2PZ2 (DOCK)
2PZ3 (DOCK)
2XNS (DOCK)
3ONW (DOCK)
3QE0 (DOCK)
3QI2 (DOCK)
3UMS (DOCK)
GNAI1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 6 0 0 0
Binding ≤ 1μM 0 0 0 0

Reactome Network (9)

Reactome ID Description Species
REACT_15333 Adenylate cyclase inhibitory pathway Homo sapiens
REACT_20653 ADP signalling through P2Y purinoceptor 12 Homo sapiens
REACT_18339 Adrenaline,noradrenaline inhibits insulin secretion Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_19327 G alpha (s) signalling events Homo sapiens
REACT_19333 G alpha (z) signalling events Homo sapiens
REACT_15457 G-protein activation Homo sapiens
REACT_15426 PLC beta mediated events Homo sapiens
REACT_18325 Regulation of insulin secretion Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
GNAI3_HUMAN P08754 CHEMBL4221 Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human 5

ADP signalling through P2Y purinoceptor 12

Uniprot Swissprot Chembl Description Number Shared
GNAI3_HUMAN P08754 CHEMBL4221 Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human 5

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
GNAI3_HUMAN P08754 CHEMBL4221 Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human 5

G alpha (s) signalling events

Uniprot Swissprot Chembl Description Number Shared
GNAI3_HUMAN P08754 CHEMBL4221 Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human 5

G alpha (z) signalling events

Uniprot Swissprot Chembl Description Number Shared
GNAI3_HUMAN P08754 CHEMBL4221 Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human 5

G-protein activation

Uniprot Swissprot Chembl Description Number Shared
GNAI3_HUMAN P08754 CHEMBL4221 Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human 5
GNAO_HUMAN P09471 CHEMBL4742 Guanine Nucleotide-binding Protein G(o), Alpha Subunit 1, Human 5

PLC beta mediated events

Uniprot Swissprot Chembl Description Number Shared
GNAI3_HUMAN P08754 CHEMBL4221 Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human 5
GNAO_HUMAN P09471 CHEMBL4742 Guanine Nucleotide-binding Protein G(o), Alpha Subunit 1, Human 5
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GNAI3_HUMAN P08754 CHEMBL4221 Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human 6 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
GNAI3_HUMAN P08754 CHEMBL4221 Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human 5
GNAO_HUMAN P09471 CHEMBL4742 Guanine Nucleotide-binding Protein G(o), Alpha Subunit 1, Human 5