| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 19 | 8 | 3 | 1 |
| Binding ≤ 1μM | 10 | 6 | 3 | 1 |
| Functional ≤ 10μM | 3 | 1 | 1 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_262979 | Class A/1 (Rhodopsin-like receptors) | Rattus norvegicus |
| REACT_233455 | G alpha (i) signalling events | Rattus norvegicus |
| REACT_196371 | Hydroxycarboxylic acid-binding receptors | Rattus norvegicus |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| HCAR2_HUMAN | Q8TDS4 | CHEMBL3785 | Nicotinic Acid Receptor 1, Human | 365 | 20 | 5 | 3 |
| HCAR2_MOUSE | Q9EP66 | CHEMBL4420 | HM74 Nicotinic Acid GPCR, Mouse | 70 | 1 | 1 | 1 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| HCAR2-1-E | HM74 Nicotinic Acid GPCR (cluster #1 Of 4), Eukaryotic | 281 | 4 | 2 | 2 |
| HCAR2-2-E | HM74 Nicotinic Acid GPCR (cluster #2 Of 4), Eukaryotic | 50 | 11 | 3 | 1 |
| HCAR2-3-E | HM74 Nicotinic Acid GPCR (cluster #3 Of 4), Eukaryotic | 31 | 1 | 1 | 0 |
| HCAR2-4-E | HM74 Nicotinic Acid GPCR (cluster #4 Of 4), Eukaryotic | 16 | 9 | 1 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| HCAR2_HUMAN | Q8TDS4 | CHEMBL3785 | Nicotinic Acid Receptor 1, Human | 12 |
| HCAR2_MOUSE | Q9EP66 | CHEMBL4420 | HM74 Nicotinic Acid GPCR, Mouse | 5 |
| HCAR3_HUMAN | P49019 | CHEMBL4421 | HM74 Nicotinic Acid GPCR, Human | 2 |
| Z50588 | Z50588 | CHEMBL373 | Canis Familiaris | 1 |
| Z50597 | Z50597 | CHEMBL376 | Rattus Norvegicus | 1 |