UCSF

Hexokinase Type IV, Human (291 Compounds)

Swissprot:
HXK4_HUMAN
Stitch:
HXK4_HUMAN
UniProt:
P35557
ChEMBL:
CHEMBL3820
Reactome:
REACT_212
REACT_13819
REACT_6804
PDB:
1GLK (DOCK)
1V4S (DOCK)
1V4T (DOCK)
3A0I (DOCK)
3F9M (DOCK)
3FGU (DOCK)
3FR0 (DOCK)
3GOI (DOCK)
3H1V (DOCK)
3ID8 (DOCK)
3IDH (DOCK)
3IMX (DOCK)
3QIC (DOCK)
3S41 (DOCK)
GCK

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 291 8 1 5
Binding ≤ 1μM 196 5 0 4
Functional ≤ 10μM 6 0 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_212 Glucose transport Homo sapiens
REACT_13819 Regulation of gene expression in beta cells Homo sapiens
REACT_6804 Regulation of Glucokinase by Glucokinase Regulatory Protein Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
HXK4_RAT P17712 CHEMBL3882 Hexokinase Type IV, Rat 1 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 2
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 2
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 2
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 2
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 2
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 2
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 2
PYGM_RABIT P00489 CHEMBL4696 Glycogen Phosphorylase, Muscle Form, Rabit 2
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 2
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 1
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 1
HXK4_RAT P17712 CHEMBL3882 Hexokinase Type IV, Rat 1
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 1
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 1
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 1
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 1
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 1
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 1
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 1
Q8IXA3_HUMAN Q8IXA3 CHEMBL5434 Casein Kinase I Gamma 1 Isoform, Human 1