UCSF
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Popular Name: 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxy-isoquinoline-3-carboxylic 1-(3,4-dihydroxybenzoyl)-6,7-dih…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
IBP1-1-E Insulin-like Growth Factor Binding Protein 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 5 0.46 Binding ≤ 10μM
IBP2-1-E Insulin-like Growth Factor Binding Protein 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 2 0.49 Binding ≤ 10μM
IBP3-1-E Insulin-like Growth Factor Binding Protein 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 6 0.46 Binding ≤ 10μM
IBP4-1-E Insulin-like Growth Factor Binding Protein 4 (cluster #1 Of 1), Eukaryotic Eukaryotes 1 0.50 Binding ≤ 10μM
IBP5-1-E Insulin-like Growth Factor Binding Protein 5 (cluster #1 Of 1), Eukaryotic Eukaryotes 6 0.46 Binding ≤ 10μM
IBP6-1-E Insulin-like Growth Factor Binding Protein 6 (cluster #1 Of 1), Eukaryotic Eukaryotes 24 0.43 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.81 -5.84 -53.27 4 8 -1 151 340.267 3 ↓

Parameters Provided:

annotation.name = IBP4_HUMAN
anotation.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN note AS n ON ci.sub_id_fk=n.sub_id_fk INNER JOIN annotation AS a ON n.anno_id_fk=a.anno_id  WHERE c.free = 1 AND a.short_desc LIKE 'IBP4\\_HUMAN' AND c.purchasable IN (1,2,4,5)    LIMIT 50

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