UCSF

Potassium Channel, Inwardly Rectifying, Subfamily J, Member 8, Human (22 Compounds)

Swissprot:
IRK8_HUMAN
Stitch:
IRK8_HUMAN
UniProt:
Q15842
ChEMBL:
CHEMBL4770
Reactome:
REACT_75775
PDB:
KCNJ8

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 22 4 1 1
Binding ≤ 1μM 10 4 1 1
Functional ≤ 10μM 129 3 1 1

Reactome Network (1)

Reactome ID Description Species
REACT_75775 ATP sensitive Potassium channels Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ABCC8_HUMAN Q09428 CHEMBL2071 Sulfonylurea Receptor 1, Human 144
ABCC9_HUMAN O60706 CHEMBL1971 Sulfonylurea Receptor 2, Human 144
IRK11_HUMAN Q14654 CHEMBL1886 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 11, Human 144
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
IRK8_RAT Q63664 CHEMBL4293 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 8, Rat 3 2 2 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
IRK11_HUMAN Q14654 CHEMBL1886 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 11, Human 96 11 5 6

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ABCC8_HUMAN Q09428 CHEMBL2071 Sulfonylurea Receptor 1, Human 144
ABCC9_HUMAN O60706 CHEMBL1971 Sulfonylurea Receptor 2, Human 144
IRK11_HUMAN Q14654 CHEMBL1886 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 11, Human 144
Z50512 Z50512 CHEMBL369 Cavia Porcellus 77
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 4
PDK2_HUMAN Q15119 CHEMBL3861 Pyruvate Dehydrogenase Kinase Isoform 2, Human 4
PDK3_HUMAN Q15120 CHEMBL3893 Pyruvate Dehydrogenase Kinase Isoform 3, Human 4
PDK4_HUMAN Q16654 CHEMBL4141 Pyruvate Dehydrogenase Kinase Isoform 4, Human 4
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 4
Z50587 Z50587 CHEMBL372 Homo Sapiens 2
KCND3_HUMAN Q9UK17 CHEMBL1964 Voltage-gated Potassium Channel Subunit Kv4.3, Human 1
Z102306 Z102306 CHEMBL613606 Aorta 1
Z50588 Z50588 CHEMBL373 Canis Familiaris 1
Z50590 Z50590 CHEMBL613488 Sus Scrofa 1
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 1