UCSF

Lysophosphatidic Acid Receptor Edg-7, Human (80 Compounds)

Swissprot:
LPAR3_HUMAN
Stitch:
LPAR3_HUMAN
UniProt:
Q9UBY5
ChEMBL:
CHEMBL3250
Reactome:
REACT_19231
REACT_18283
REACT_18365
PDB:
LPAR3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 80 5 0 1
Binding ≤ 1μM 53 3 0 1
Functional ≤ 10μM 61 15 1 0

Reactome Network (3)

Reactome ID Description Species
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_18365 Lysosphingolipid and LPA receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
LPAR1_HUMAN Q92633 CHEMBL3819 Lysophosphatidic Acid Receptor Edg-2, Human 68
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 27
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 2

G alpha (q) signalling events

Uniprot Swissprot Chembl Description Number Shared
LPAR1_HUMAN Q92633 CHEMBL3819 Lysophosphatidic Acid Receptor Edg-2, Human 68
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 27
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 2

Lysosphingolipid and LPA receptors

Uniprot Swissprot Chembl Description Number Shared
LPAR1_HUMAN Q92633 CHEMBL3819 Lysophosphatidic Acid Receptor Edg-2, Human 68
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 27
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
LPAR3_RAT Q8K5E0 CHEMBL4424 Lysophosphatidic Acid Receptor Edg-7, Rat 19 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
LPAR1_HUMAN Q92633 CHEMBL3819 Lysophosphatidic Acid Receptor Edg-2, Human 59 5 0 0
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 59 3 0 0
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 1 1 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
LPAR3-1-E Lysophosphatidic Acid Receptor Edg-7 (cluster #1 Of 2), Eukaryotic 83 4 0 1
LPAR3-2-E Lysophosphatidic Acid Receptor Edg-7 (cluster #2 Of 2), Eukaryotic 20 1 0 0
Uniprot Swissprot Chembl Description Number Shared
LPAR1_HUMAN Q92633 CHEMBL3819 Lysophosphatidic Acid Receptor Edg-2, Human 68
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 27
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 14
Z50587 Z50587 CHEMBL372 Homo Sapiens 5
ENPP2_HUMAN Q13822 CHEMBL3691 Autotaxin, Human 3
LPAR1_RAT P61794 CHEMBL4595 Lysophosphatidic Acid Receptor Edg-2, Rat 2
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 2