UCSF

Neurokinin 2 Receptor, Rat (36 Compounds)

Swissprot:
NK2R_RAT
Stitch:
NK2R_RAT
UniProt:
P16610
ChEMBL:
CHEMBL4554
Reactome:
REACT_263374
REACT_252978
PDB:
Tacr2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 36 1 0 2
Binding ≤ 1μM 35 1 0 2
Functional ≤ 10μM 14 0 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_263374 G alpha (q) signalling events Rattus norvegicus
REACT_252978 Tachykinin receptors bind tachykinins Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
NK1R_RAT P14600 CHEMBL4027 Neurokinin 1 Receptor, Rat 9
NK3R_RAT P16177 CHEMBL3154 Neurokinin 3 Receptor, Rat 2

Tachykinin receptors bind tachykinins

Uniprot Swissprot Chembl Description Number Shared
NK1R_RAT P14600 CHEMBL4027 Neurokinin 1 Receptor, Rat 9
NK3R_RAT P16177 CHEMBL3154 Neurokinin 3 Receptor, Rat 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NK2R_BOVIN P05363 CHEMBL4815 Neurokinin 2 Receptor, Bovin 5 0 0 1
NK2R_CAVPO Q64077 CHEMBL2647 Neurokinin 2 Receptor, Guinea Pig 14 0 0 0
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 834 11 2 6
NK2R_MOUSE P30549 CHEMBL2813 Neurokinin 2 Receptor, Mouse 27 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 22
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 18
NK1R_RAT P14600 CHEMBL4027 Neurokinin 1 Receptor, Rat 9
NK1R_CAVPO P30547 CHEMBL3942 Neurokinin 1 Receptor, Guinea Pig 7
NK2R_BOVIN P05363 CHEMBL4815 Neurokinin 2 Receptor, Bovin 3
NK3R_HUMAN P29371 CHEMBL4429 Neurokinin 3 Receptor, Human 2
NK3R_RAT P16177 CHEMBL3154 Neurokinin 3 Receptor, Rat 2
Z50594 Z50594 CHEMBL375 Mus Musculus 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
NK3R_CAVPO P30098 CHEMBL3799 Neurokinin 3 Receptor, Guinea Pig 1