UCSF

Nitric-oxide Synthase, Endothelial, Mouse (4 Compounds)

Swissprot:
NOS3_MOUSE
Stitch:
NOS3_MOUSE
UniProt:
P70313
ChEMBL:
CHEMBL2643
Reactome:
REACT_221264
REACT_245499
REACT_226405
REACT_215995
REACT_198345
REACT_199047
REACT_261840
PDB:
Nos3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 4 1 1 1
Binding ≤ 1μM 1 0 0 0

Reactome Network (7)

Reactome ID Description Species
REACT_221264 eNOS activation Mus musculus
REACT_245499 Nitric oxide stimulates guanylate cyclase Mus musculus
REACT_226405 NOSIP mediated eNOS trafficking Mus musculus
REACT_215995 NOSTRIN mediated eNOS trafficking Mus musculus
REACT_198345 Phagosomal maturation (early endosomal stage) Mus musculus
REACT_199047 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation Mus musculus
REACT_261840 VEGFR2 mediated vascular permeability Mus musculus
Uniprot Swissprot Chembl Description Number Shared
NOS1_MOUSE Q9Z0J4 CHEMBL4719 Nitric-oxide Synthase, Brain, Mouse 4
NOS2_MOUSE P29477 CHEMBL3464 Nitric Oxide Synthase, Inducible, Mouse 4

Phagosomal maturation (early endosomal stage)

Uniprot Swissprot Chembl Description Number Shared
NOS1_MOUSE Q9Z0J4 CHEMBL4719 Nitric-oxide Synthase, Brain, Mouse 4
NOS2_MOUSE P29477 CHEMBL3464 Nitric Oxide Synthase, Inducible, Mouse 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NOS3_BOVIN P29473 CHEMBL4802 Nitric-oxide Synthase, Endothelial, Bovin 41 7 4 5
NOS3_HUMAN P29474 CHEMBL4803 Nitric-oxide Synthase, Endothelial, Human 302 50 14 18
NOS3_PIG Q28969 CHEMBL3809 Nitric-oxide Synthase, Endothelial, Pig 8 0 0 2
NOS3_RAT Q62600 CHEMBL1075230 Nitric Oxide Synthase, Endothelial, Rat 5 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NOS1_MOUSE Q9Z0J4 CHEMBL4719 Nitric-oxide Synthase, Brain, Mouse 27 4 2 2
NOS2_MOUSE P29477 CHEMBL3464 Nitric Oxide Synthase, Inducible, Mouse 194 27 8 13

Clustered By Gene (0)

Clustered By Organism (6)

Code Description Substances Purchasable Natural In Man
NOS3-1-E Nitric Oxide Synthase, Endothelial (cluster #1 Of 7), Eukaryotic 109 20 9 8
NOS3-2-E Nitric Oxide Synthase, Endothelial (cluster #2 Of 7), Eukaryotic 109 1 0 7
NOS3-3-E Nitric Oxide Synthase, Endothelial (cluster #3 Of 7), Eukaryotic 80 10 0 3
NOS3-4-E Nitric Oxide Synthase, Endothelial (cluster #4 Of 7), Eukaryotic 2 1 1 1
NOS3-5-E Nitric Oxide Synthase, Endothelial (cluster #5 Of 7), Eukaryotic 5 4 0 2
NOS3-6-E Nitric Oxide Synthase, Endothelial (cluster #6 Of 7), Eukaryotic 23 18 6 2
NOS3-7-E Nitric Oxide Synthase, Endothelial (cluster #7 Of 7), Eukaryotic 16 1 0 0
Uniprot Swissprot Chembl Description Number Shared
NOS1_MOUSE Q9Z0J4 CHEMBL4719 Nitric-oxide Synthase, Brain, Mouse 4
NOS2_MOUSE P29477 CHEMBL3464 Nitric Oxide Synthase, Inducible, Mouse 4
NOS1_HUMAN P29475 CHEMBL3568 Nitric-oxide Synthase, Brain, Human 1
NOS1_RAT P29476 CHEMBL3048 Nitric-oxide Synthase, Brain, Rat 1
NOS2_HUMAN P35228 CHEMBL4481 Nitric Oxide Synthase, Inducible, Human 1
NOS3_BOVIN P29473 CHEMBL4802 Nitric-oxide Synthase, Endothelial, Bovin 1
NOS3_HUMAN P29474 CHEMBL4803 Nitric-oxide Synthase, Endothelial, Human 1