UCSF

P2X Purinoceptor 7, Human (60 Compounds)

Swissprot:
P2RX7_HUMAN
Stitch:
P2RX7_HUMAN
UniProt:
Q99572
ChEMBL:
CHEMBL4805
Reactome:
REACT_75808
PDB:
P2RX7

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 60 9 0 0
Binding ≤ 1μM 58 9 0 0
Functional ≤ 10μM 576 21 0 0

Reactome Network (1)

Reactome ID Description Species
REACT_75808 The NLRP3 inflammasome Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
P2RX7_MOUSE Q9Z1M0 CHEMBL5183 P2X Purinoceptor 7, Mouse 1 0 0 0
P2RX7_RAT Q64663 CHEMBL2496 P2X Purinoceptor 7, Rat 19 8 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
P2RX1_HUMAN P51575 CHEMBL2094 P2X Purinoceptor 1, Human 1 1 1 0
P2RX3_HUMAN P56373 CHEMBL2998 P2X Purinoceptor 3, Human 1 1 1 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
P2RX7-1-E P2X Purinoceptor 7 (cluster #1 Of 2), Eukaryotic 59 13 0 0
P2RX7-2-E P2X Purinoceptor 7 (cluster #2 Of 2), Eukaryotic 13 2 0 0
Uniprot Swissprot Chembl Description Number Shared
P2RX7_RAT Q64663 CHEMBL2496 P2X Purinoceptor 7, Rat 244
Z80563 Z80563 CHEMBL615025 U-373 MG ( Glioblastoma Cells) 14
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 4
P2RX1_HUMAN P51575 CHEMBL2094 P2X Purinoceptor 1, Human 3
P2RX2_HUMAN Q9UBL9 CHEMBL2531 P2X Purinoceptor 2, Human 3
P2RX3_RAT P49654 CHEMBL4824 P2X Purinoceptor 3, Rat 3
P2RX4_HUMAN Q99571 CHEMBL2104 P2X Purinoceptor 4, Human 3
P2RX5_HUMAN Q93086 CHEMBL4942 P2X Purinoceptor 5, Human 3
P2RX6_HUMAN O15547 CHEMBL2670 P2X Purinoceptor 6, Human 3
Z50587 Z50587 CHEMBL372 Homo Sapiens 2
Z81011 Z81011 CHEMBL614840 Human Cell Lines 2
P2RX3_HUMAN P56373 CHEMBL2998 P2X Purinoceptor 3, Human 1
P2RX7_MOUSE Q9Z1M0 CHEMBL5183 P2X Purinoceptor 7, Mouse 1