UCSF

Proteasome Component C5, Yeast (2 Compounds)

Swissprot:
PSB1_YEAST
Stitch:
PSB1_YEAST
UniProt:
P23724
ChEMBL:
CHEMBL4904
Reactome:
REACT_189060
REACT_189250
REACT_245912
REACT_189047
REACT_189025
REACT_83036
REACT_100522
REACT_230653
REACT_245870
PDB:
1FNT (DOCK)
1G0U (DOCK)
1G65 (DOCK)
1JD2 (DOCK)
1RYP (DOCK)
1VSY (DOCK)
1Z7Q (DOCK)
2F16 (DOCK)
2FAK (DOCK)
2GPL (DOCK)
2ZCY (DOCK)
3BDM (DOCK)
3D29 (DOCK)
3DY3 (DOCK)
3DY4 (DOCK)
3E47 (DOCK)
3GPJ (DOCK)
3GPT (DOCK)
3GPW (DOCK)
3HYE (DOCK)
3L5Q (DOCK)
3MG0 (DOCK)
3MG4 (DOCK)
3MG6 (DOCK)
3MG7 (DOCK)
3MG8 (DOCK)
3NZJ (DOCK)
3NZW (DOCK)
3NZX (DOCK)
3OEU (DOCK)
3OEV (DOCK)
3OKJ (DOCK)
3SHJ (DOCK)
3TDD (DOCK)
PRE7

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 2 0 0 0
Binding ≤ 1μM 0 0 0 0

Reactome Network (9)

Reactome ID Description Species
REACT_189060 Antigen processing: Ubiquitination & Proteasome degradation Saccharomyces cerevisiae
REACT_189250 AUF1 (hnRNP D0) destabilizes mRNA Saccharomyces cerevisiae
REACT_245912 CDK-mediated phosphorylation and removal of Cdc6 Saccharomyces cerevisiae
REACT_189047 Cross-presentation of soluble exogenous antigens (endosomes) Saccharomyces cerevisiae
REACT_189025 ER-Phagosome pathway Saccharomyces cerevisiae
REACT_83036 Orc1 removal from chromatin Saccharomyces cerevisiae
REACT_100522 Regulation of activated PAK-2p34 by proteasome mediated degradation Saccharomyces cerevisiae
REACT_230653 SCF-beta-TrCP mediated degradation of Emi1 Saccharomyces cerevisiae
REACT_245870 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Saccharomyces cerevisiae
Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2

AUF1 (hnRNP D0) destabilizes mRNA

Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2

CDK-mediated phosphorylation and removal of Cdc6

Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2

Cross-presentation of soluble exogenous antigens (endosomes)

Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2

ER-Phagosome pathway

Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2

Orc1 removal from chromatin

Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2

Regulation of activated PAK-2p34 by proteasome mediated degradation

Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2

SCF-beta-TrCP mediated degradation of Emi1

Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A

Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PSB1_HUMAN P20618 CHEMBL4208 Proteasome Component C5, Human 1 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2 0 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PSB1-1-E Proteasome Component C5 (cluster #1 Of 1), Eukaryotic 1 0 0 0
PSB1-1-F Proteasome Component C5 (cluster #1 Of 1), Fungal 2 0 0 0
Uniprot Swissprot Chembl Description Number Shared
PSB5_YEAST P30656 CHEMBL4659 Proteasome Macropain Subunit PRE2, Yeast 2