UCSF

NAD-dependent Deacetylase Sirtuin 2, Human (78 Compounds)

Swissprot:
SIRT2_HUMAN
Stitch:
SIRT2_HUMAN
UniProt:
Q8IXJ6
ChEMBL:
CHEMBL4462
PDB:
1J8F (DOCK)
SIRT2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 78 13 2 3
Binding ≤ 1μM 4 2 0 0

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SIRT1_HUMAN Q96EB6 CHEMBL4506 NAD-dependent Deacetylase Sirtuin 1, Human 67 17 2 0
SIRT3_HUMAN Q9NTG7 CHEMBL4461 NAD-dependent Deacetylase Sirtuin 3, Human 2 1 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
SIRT2-1-E NAD-dependent Deacetylase Sirtuin 2 (cluster #1 Of 3), Eukaryotic 15 1 0 0
SIRT2-2-E NAD-dependent Deacetylase Sirtuin 2 (cluster #2 Of 3), Eukaryotic 2 1 0 0
SIRT2-3-E NAD-dependent Deacetylase Sirtuin 2 (cluster #3 Of 3), Eukaryotic 62 11 2 3
Uniprot Swissprot Chembl Description Number Shared
SIRT1_HUMAN Q96EB6 CHEMBL4506 NAD-dependent Deacetylase Sirtuin 1, Human 20
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 3
KCC2D_HUMAN Q13557 CHEMBL2801 CaM Kinase II Delta, Human 3
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 3
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 3
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 3
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 3
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 3
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 3
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 3
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 3
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 3
HST2_YEAST P53686 CHEMBL5933 NAD-dependent Deacetylase HST2, Yeast 2
KPCA_RAT P05696 CHEMBL2855 Protein Kinase C Alpha, Rat 2
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 2
KPCB_RAT P68403 CHEMBL3020 Protein Kinase C Beta, Rat 2
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 2
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 2
KPCD_RAT P09215 CHEMBL3633 Protein Kinase C Delta, Rat 2
KPCE_RAT P09216 CHEMBL3424 Protein Kinase C Epsilon, Rat 2
KPCG_RAT P63319 CHEMBL3604 Protein Kinase C Gamma, Rat 2
KPCL_RAT Q64617 CHEMBL3990 Protein Kinase C Eta, Rat 2
KPCT_RAT Q9WTQ0 CHEMBL4563 Protein Kinase C Theta, Rat 2
KPCZ_RAT P09217 CHEMBL5379 Protein Kinase C Zeta, Rat 2
SIRT3_HUMAN Q9NTG7 CHEMBL4461 NAD-dependent Deacetylase Sirtuin 3, Human 2
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 2
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 1
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 1
AMPH_ECOLI P0AD70 CHEMBL4413 Penicillin-binding Protein AmpH, Ecoli 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
KAPCA_BOVIN P00517 CHEMBL2654 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin 1
KAPCA_RAT P27791 CHEMBL3390 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rat 1
KAPCB_BOVIN P05131 CHEMBL3279 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Bovin 1
KS6A3_HUMAN P51812 CHEMBL2345 Ribosomal Protein S6 Kinase Alpha 3, Human 1
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 1
KS6B1_HUMAN P23443 CHEMBL4501 Ribosomal Protein S6 Kinase 1, Human 1
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 1
MDHM_HUMAN P40926 CHEMBL5917 Malate Dehydrogenase, Mitochondrial, Human 1
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 1